1017-76-1

Usage

Uses

Used in Biochemistry and Molecular Biology Research:
S-Benzyl-DL-homocysteine is utilized as a research compound for the synthesis of peptides and proteins, contributing to the understanding of their structure, function, and interactions within biological systems.
Used in Enzyme Substrate Applications:
In the field of enzymology, S-Benzyl-DL-homocysteine serves as a substrate for enzymes that are involved in the synthesis of S-adenosylmethionine, a coenzyme crucial for various biochemical reactions in the body, including methylation processes and the production of polyamines.
Used in Pharmaceutical Development:
S-BENZYL-DL-HOMOCYSTEINE's role in the synthesis of S-adenosylmethionine suggests potential applications in the development of pharmaceuticals targeting conditions related to methionine metabolism and S-adenosylmethionine synthesis, which could have implications for a range of health-related issues.
Used in Diagnostics:
Due to its involvement in biochemical pathways, S-Benzyl-DL-homocysteine may also be employed in diagnostic assays to evaluate the activity of enzymes or the status of metabolic pathways, providing insights into various diseases and conditions.

InChI:InChI=1/C11H15NO2S/c13-11(14)10(6-7-15)12-8-9-4-2-1-3-5-9/h1-5,10,12,15H,6-8H2,(H,13,14)/t10-/m0/s1

Upstream product

• 59-51-8 DL-methionine 
• 462-10-2 DL-homocystine 
• 100-44-7 benzyl chloride 
• 7647-01-0 hydrogenchloride 
• 7732-18-5 water 
• 151-50-8 potassium cyanide 
• 454-29-5 2-amino-4-mercaptobutyric acid 
• 100-39-0 benzyl bromide 
• 100-53-8 phenylmethanethiol 
• 4332-51-8 1-(benzylthio)-2-chloroethane 
• 32362-99-5 benzylthioacetate 
• 141-52-6 sodium ethanolate 
• 5394-22-9 3,6-bis-(β-chloroethyl)-2,5-diketopiperazine 
• 124-41-4 sodium methylate 

Downstream Products

• 82611-67-4 S-benzyl-N-benzyloxycarbonyl-DL-homocysteine 
• 57512-02-4 S-(N-Benzyloxycarbonyl-3-amino-propyl)-homocystein 
• 70198-04-8 1-benzyl-3-carboxy-isothiazolidinium betaine 
• 95821-41-3 S-Benzyl-DL-homocystein-benzylester 
• 1108791-59-8 N-(S-benzyl-DL-homocysteinyl)-glycine ethyl ester 
• 101265-70-7 N-(S-benzyl-DL-homocysteinyl)-glycine 
• 102164-48-7 N-acetyl-S-benzyl-L-homocysteine anilide 
• 1195337-79-1 S-benzyl-N-acetyl-D-homocysteine 
• 7689-60-3 S-benzyl-L-homocysteine 
• 2598-44-9 S-(2-hydroxyethyl)-D,L-homocysteine 
• 100192-80-1 4-(2-benzylsulfanyl-ethyl)-oxazolidine-2,5-dione 
• 100610-06-8 S-benzyl-N-acetyl-DL-homocysteine 
• 10593-85-8 DL-homocysteine thiolactone 
• 59-51-8 DL-methionine 

Relevant academic research and scientific papers

A Biocatalytic Cascade for Versatile One-Pot Modification of mRNA Starting from Methionine Analogues

Methyltransferases have proven useful to install functional groups site-specifically in different classes of biomolecules when analogues of their cosubstrate S-adenosyl-l-methionine (AdoMet) are available. Methyltransferases have been used to address different classes of RNA molecules selectively and site-specifically, which is indispensable for biophysical and mechanistic studies as well as labeling in the complex cellular environment. However, the AdoMet analogues are not cell-permeable, thus preventing implementation of this strategy in cells. We present a two-step enzymatic cascade for site-specific mRNA modification starting from stable methionine analogues. Our approach combines the enzymatic synthesis of AdoMet with modification of the 5′ cap by a specific RNA methyltransferase in one pot. We demonstrate that a substrate panel including alkene, alkyne, and azido functionalities can be used and further derivatized in different types of click reactions.

A SIMPLE PREPARATION OF S-ALKYL HOMOCYSTEINE DERIVATIVES: S-PHOSPHONOMETHYL HOMOCYSTEINES AS INHIBITORS OF GLUTAMINE SYNTHETASE

A facile synthesis of S-alkyl homocysteines is described which features the coupling of sodium alkyl thiolates with methyl 4-bromo-2-phthalimidobutyrate, followed by hydrolysis.This approach is exemplified by the synthesis of S-phosphonomethyl homocysteine sulfone, a new inhibitor of the enzyme glutamine synthetase.