10255-99-9Relevant articles and documents
Copper(I)-catalyzed N-arylation of N1,N3- dibenzylmalonamide and N1,N3-dibutylmalonamide followed by cleavage of the malonyl group with aryl halides under ligand-free conditions
Zheng,Xu,Shi,Ren,Lu,Zhou
, p. 1117 - 1122 (2013)
We primarily developed a practical and convenient protocol to synthesize of aromatic amines based on CuI-catalyzed N-arylation of N1,N 3-dibenzylmalonamide and N1,N3- dibutylmalonamide followed by cleavage of the malonyl group with aryl halides under ligand-free conditions giving good yields.
Atom-economic amide synthesis by using an iron-substituted polyoxometalate catalyst
Shi, Da,Wang, Aiping,Wang, Jingjing,Xie, Ya,Yu, Han
supporting information, p. 1127 - 1130 (2022/02/03)
We report an efficient and economical amidation strategy by using a polyoxometalate-based iron catalyst that affords the corresponding amide products in good yields. All of the aliphatic, aromatic and heterocyclic substrates are produced in high yields without additional base or organic ligands. Most importantly, the first example of heterogeneous iron(iii)-catalyzed formation of the diamides is developed.
Palladium-catalyzed asymmetric haloiminolactonization of D-allylmalonamides
Kuriyama, Masami,Yamamoto, Kosuke,Ishimaru, Keiko,Fujimura, Noriyuki,Minato, Daishiro,Onomura, Osamu
, p. 744 - 754 (2019/04/26)
A catalyst composed of 10 mol% of Pd(OAc)2 and (R,R)-PhBox was proven to be effective in the asymmetric haloiminolactonization of D-allylmalonamides with N-halosuccinimides, giving the dihalogenated cyclic products with good diastereomeric ratio (up to 89/11) and enantiomeric excess (up to 72% ee).
