109283-53-6Relevant academic research and scientific papers
Nitrogen ligand complexes of metal chlorides as effective catalysts for the highly regio- and chemoselective silylation of hydroxyl groups with hexamethyldisilazane (HMDS) at room temperature
Firouzabadi,Sardarian,Khayat,Karimi,Tangestaninejad
, p. 2709 - 2719 (1997)
Zn(bipy)3Cl2, Fe(bipy)Cl3, and Fe(tpp)Cl are effective catalysts for silylation of hydroxy groups with HMDS at room temperature in dry CH3CN. High selectivity is observed between primary and secondary hydroxy fu
A mild and efficient method for chemoselective silylation of alcohols using hexamethyldisilazane in the presence of silica chloride
Shirini, Farhad,Zolfigol, Mohammad Ali,Mohammadi, Kamal
, p. 1567 - 1570 (2003)
Reaction of alcohols with hexamethyldisilazane in the presence of silica chloride provides efficiently the corresponding trimethylsilyl ethers. This system discriminates absolutely amines and thiols from alcohols.
Selective silylation of alcohols, phenols and oximes using N-chlorosaccharin as an efficient catalyst under mild and solvent-free conditions
Aghapour, Ghasem,Moghaddam, Ali Kazemi,Nadali, Samaneh
, p. 197 - 203 (2015)
Efficient silylation of OH group in alcohols, phenols and oximes is described using a catalytic amount of N-chlorosaccharin and hexamethyldisilazane (HMDS) under mild and solvent-free conditions. This silylation reaction can be carried out with excellent and interesting various selectivities.
Lanthanum trichloride: An efficient catalyst for the silylation of hydroxyl groups by activating hexamethyldisilazane (HMDS)
Narsaiah, Akkirala Venkat
, p. 3614 - 3618 (2007)
A variety of hydroxy functional groups was protected as their corresponding trimethylsilyl ethers using HMDS in the presence of lanthanum trichloride. The catalyst LaCl3 activates the HMDS and accelerates the reaction under mild reaction conditions at room temperature to afford the corresponding silylated products in excellent yields.
Trimethylsilylazide: A Highly Reactive Silylating Agent for Primary and Secondary Alcohols
Sinou, D.,Emziane, M.
, p. 1045 - 1046 (1986)
Trimethylsilylazide reacts very rapidly with primary and secondary alcohols at room temperature to give high yields of trimethylsilyl ethers.
Introduction of a New Ionic Liquid Catalyst for the Trimethylsilyl and Tetrahydropyranyl Protection of Alcohols
Shirini, Farhad,Abedini, Masoumeh,Mahmoodi, Nosratollah,Biglari, Mohammad,Safarpoor Nikoo Langrudi, Mohaddeseh
, p. 1912 - 1921 (2015)
1,1'-Disulfo-[2,2'-bipyridine]-1,1'-hydrogen sulfate, BiPy(SO3H)2(HSO4)2, is prepared and identified as a new ionic liquid. This reagent was used for the promotion of the chemoselective trimethylsilyl and tetrahydropyranyl protection of alcohols. All reactions were performed under mild reaction conditions in high to excellent yields. Ease of the preparation of the heterogeneous catalyst, simplicity and easy work-up procedure, high reaction rates, and recyclability and reusability of the catalyst are the main advantages of this method.
Al(HSO4)3 as an efficient reagent for the selective trimethylsilylation of primary alcohols under solvent-free conditions
Shirini, Farhad,Zolfigol, Mohammad Ali,Abedini, Masoumeh
, p. 2299 - 2302 (2005)
Primary alcohols are selectively trimethylsilylated using Hexamethyldisilazane (HMDS) in the presence of a catalytic amount of Al(HSO 4)3 under solvent free conditions. Copyright Taylor & Francis Inc.
A novel and highly efficient method for the direct conversion of aryl aldehyde bisulfite adducts to their aryl trimethylsilyl ethers in a one-pot manner catalyzed by montmorillonite K-10
Khodaei, Mohammad M.,Khosropour, Ahmad R.,Abbasi, Jamshide
, p. 93 - 97 (2006)
A new, convenient, and chemoselective method has been developed for the one-pot conversion of aryl aldehyde bisulfite adducts to the corresponding trimethylsilyl ethers. Copyright Taylor & Francis LLC.
Indium tribromide: An efficient catalyst for the silylation of hydroxy groups by the activation of hexamethyldisilazane
Yadav,Reddy,Basak,Baishya,Venkat Narsaiah
, p. 3831 - 3834 (2006)
A variety of substrates containing hydroxy groups have been protected as their corresponding trimethylsilyl ethers using 1,1,1,3,3,3-hexamethyldisilazane in the presence of indium tribromide. The catalyst indium tribromide activates the 1,1,1,3,3,3-hexamethyldisilazane and accelerates the reaction under mild reaction conditions at room temperature. Georg Thieme Verlag Stuttgart.
Zinc mediated reactions in organic synthesis: Efficient synthesis of silyl ethers under mild conditions
Bandgar, Babasaheb Pandurang,Chavare, Satish Navnath,Pandit, Shivaji Sandu
, p. 125 - 128 (2005)
General and practical method for the syn the sis of silyl ethers in the presence of zinc powder under mild conditions has been described.
