1116-40-1Relevant articles and documents
One-Pot Synthesis of Symmetrical Tertiary and Secondary Amines from Carbonyl Compounds, Ammonium Carbonate and Carbon Monoxide as a Reductant
Muratov, Karim,Afanasyev, Oleg I.,Kuchuk, Ekaterina,Runikhina, Sofiya,Chusov, Denis
supporting information, p. 6557 - 6560 (2019/10/22)
Rh-catalyzed one-step synthesis of tertiary and secondary amines from aldehydes and ketones, ammonium carbonate serving as nitrogen source, and carbon monoxide as a reducing agent has been developed. Aliphatic and aromatic aldehydes lead to the corresponding tertiary symmetrical amines in 69–83 % yields. Aromatic and aliphatic ketones lead to the corresponding secondary symmetrical amines which were obtained in 62–79 % yields.
An efficient synthesis of tertiary amines from nitriles in aprotic solvents
Shares, Jonathan,Yehl, Jenna,Kowalsick, Amanda,Byers, Philip,Haaf, Michael P.
experimental part, p. 4426 - 4428 (2012/09/25)
Tertiary amines are utilized extensively as non-nucleophilic proton scavengers for a number of organic transformations. Herein we report the efficient syntheses of tertiary alkyl amines from their corresponding alkyl nitriles in the presence of a heterogeneous palladium catalyst and a source of dihydrogen in aprotic solvents. The reaction is atom economic, the conditions are mild, and the isolated yields are virtually quantitative. The degree of amine alkylation shows some solvent dependency; in polar protic solvents such as ethanol or methanol, the reaction affords a mixture of products with the secondary alkyl amine as the major product.
REDUCTIVE AMINATION OF ISOBUTYRALDEHYDE TO ISOBUTYLAMINES IN PRESENCE OF VARIOUS HYDROGENATION CATALYSTS
Smaeva, T. P.,Yakushin, M. I.,Akulova, N. G.,Bazyleva, R. V.,Lebedeva, N. V.
, p. 1039 - 1043 (2007/10/02)
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