122999-13-7

Upstream product

• 43112-38-5 3-(trimethylsilyl)-2-oxazolidinone 
• 89-78-1 2-Isopropyl-5-methyl-cyclohexanol 
• 89-78-1 menthol 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 75-77-4 chloro-trimethyl-silane 
• 754-05-2 ethenyltrimethylsilane 
• 91898-16-7 2-Ethoxymethoxy-1-isopropyl-4-methyl-cyclohexane 
• 91898-14-5 1-Isopropyl-2-methoxymethoxy-4-methyl-cyclohexane 
• 2216-51-5 (-)-menthol 
• 4648-54-8 trimethylsilylazide 
• 762-72-1 allyl-trimethyl-silane 
• 27607-77-8 trimethylsilyl trifluoromethanesulfonate 
• 167702-76-3 (1S,2R,4R)-1-Isopropyl-2-(1-methoxy-1-methyl-ethoxy)-4-methyl-cyclohexane 
• 363603-37-6 acetaldehyde ethyl menthyl acetal 

Downstream Products

• 89-48-5 2-isopropyl-5-methylcyclohexyl acetate 
• 2230-89-9 menthyl formate 
• 10458-14-7 Menthone 
• 34513-32-1 O-(1R,2S,5R)-(-)-menthyl (S)-benzenesulfinate 
• 97672-26-9 R-(-)-menthol angelate 
• 72447-47-3 (-)-menthyl (Z)-2-methyl-2-butenoate 
• 125425-47-0 (-)-menthyl fluoride 
• 10458-14-7 (2R,5S)-menthone 
• 2623-23-6 L-menthyl acetate 
• 2230-82-2 menthyl tosylate 
• 100-51-6 benzyl alcohol 
• 136375-73-0 [[[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]oxy]methyl]benzene 
• 125425-48-1 (-)-menthyltetrafluorophosphorane 
• 125425-50-5 (-)-menthylphosphonofluoridic acid 

Relevant academic research and scientific papers

Magnesium hydrogensulfate [Mg(HSO4)2] as an efficient catalyst for the preparation of silyl ethers, dibenzo[a,j]xanthenes, and octahydroxanthene derivatives

Magnesium hydrogensulfate [Mg(HSO4)2], as a heterogeneous solid acid catalyst, has been used for the mild formation of trimethylsilyl (TMS) ethers from various primary, secondary, and tertiary aliphatic alcohols; aromatic alcohols; a

Tungstophosphoric acid (H3PW12O40) as a heterogeneous inorganic catalyst. Activation of hexamethyldisilazane (HMDS) by tungstophosphoric acid for efficient and selective solvent-free O-silylation reactions

The role of tungstophosphoric acid (H3PW12O40) as heterogeneous organic catalysts was discussed. Activation of hexamethyldisilazane by tungstophosphoric acid for efficient and selective solvent-free O-silylation reactions

USE OF ALLYLSILANES AS A NEW TYPE OF SILYLATING AGENT FOR ALCOHOLS AND CARBOXYLIC ACIDS

A new convenient route to silyl ethers and esters from alcohols and carboxylic acids using allylsilanes in the presence of an acid catalyst in acetonitrile was developed.The present method is also applicable to t-butyldimethylsilylation.

Highly efficient O-silylation of alcohol with vinylsilane using a Rh(l)/HCl catalyst at room temperature

Highly efficient O-silylation of alcohol with vinylsilane was developed using a catalyst system consisting of [(COE)2RhCl]2 and HCl. In this reaction, a key intermediate is chlorosilane, generated from vinylsilane and HCl, which can be regenerated in the catalytic cycle. Various alcohols and vinylsilanes were applied to the preparation of silyl ether compounds with this catalyst system.

Highly efficient chemo- and regioselective silylation of -OH groups and cyanosilylation of aldehydes promoted by TiCl2(OTf)-SiO2 as a new recyclable catalyst

TiCl2(OTf)-SiO2 as an easy handling recyclable catalyst was applied for trimethylsilylation of diethyl α-hydroxyphosphonates, alcohols and phenols with high selectivity using HMDS as a silylating agent. Cyanotrimethylsilyl ethers were also obtained in excellent yields from treatment of aldehydes with TMSCN in the presence of this catalyst.

Silylation of alcohols and phenols using hexamethyldisilazane catalyzed by N,N'-diiodo-N,N'-1,2-ethanediyl bis(p-toluenesulfonamide) under solvent-free and microwave conditions

N,N'-Diiodo-N,N'-1,2-ethanediyl bis(p-toluenesulfonamide) (NIBTS) is an effective catalyst for the silylation of alcohols and phenols using hexamethyldisilazane under solvent-free and microwave conditions. Supplemental materials are available for this art

Trimethylsilylation of hydroxyl group with 1,1,1,3,3,3-hexamethyldisilazane (HMDS) catalyzed by tribromomelamine (TBM)

Tribromomelamine (TBM) can be used as a novel catalyst for the trimethylsilylation of alcohols and phenols with 1,1,1,3,3,3- hexamethyldisilazane (HMDS). A wide variety of hydroxyl groups were selectively protected in CH2Cl2/CH3CN under mild conditions.

1,3-Dichloro-5,5-dimethylhydantoin (DCH) and trichloromelamine (TCM) as efficient catalysts for the chemoselective trimethylsilylation of hydroxyl group with 1,1,1,3,3,3-hexamethyldisilazane (HMDS) under mild conditions

A highly convenient method for the trimethylsilylation of alcohols and phenols via treatment by hexamethyldisilazane in the presence of 1,3-dichloro-5,5-dimethylhydantoin (DCH) and/or trichloromelamine (TCM) as a catalyst has been developed. A wide variety of hydroxyl groups were selectively protected in CH2Cl2/CH3CN under mild conditions.

Improved preparation of N-trimethylsilylpyridinium triflate, N- triphenylsilylpyridinium triflate, N-triisopropylsilylpyridinium triflate and their use in silylating alcohols to silyl ethers

N-Silylpyridinium triflates 1a-c have been prepared in excellent yield from the corresponding allyl silanes by reaction with triflic acid followed by pyridine. Compounds 1a-c were used to prepare silyl ethers from alcohols in generally high yield. A convenient procedure has been developed which enables the silylation of alcohols without an aqueous workup in the product isolation.

Nanoporous Na+-montmorillonite perchloric acid as an efficient and recyclable catalyst for the chemoselective protection of hydroxyl groups

Nanoporous Na+-montmorillonite perchloric acid as a novel heterogeneous reusable solid acid catalyst was easily prepared by treatment of Na+-montmorillonite as a cheap and commercially available support with perchloric acid. The catalyst was characterized using a variety of techniques including X-ray powder diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), thermogravimetric analysis (TGA), energy dispersive X-ray spectroscopy (EDX), pH analysis and determination of the Hammett acidity function. The prepared reagent showed excellent catalytic activity for the chemoselective conversion of alcohols and phenols to their corresponding trimethylsilyl ethers with 1,1,1,3,3,3-hexamethyldisilazane (HMDS) at room temperature. Deprotection of the resulting trimethylsilyl ethers can also be carried out using the same catalyst in ethanol. All reactions were performed under mild and completely heterogeneous reaction conditions in good to excellent yields. The notable advantages of this protocol are: short reaction times, high yields, availability and low cost of the reagent, easy work-up procedure and the reusability of the catalyst during a simple filtration.