125-12-2Relevant articles and documents
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Wagner,Moycho,Zienkowski
, p. 1037 (1904)
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Chapman,N.B. et al.
, p. 3634 - 3643 (1960)
Heterogeneous zeolite-based catalyst for esterification of α-pinene to α-terpinyl acetate
Wijayati, Nanik,Kusumastuti, Ella,Alighiri, Dante,Rohmawati, Baiti,Lusiana, Retno Ariadi
, p. 399 - 403 (2019)
The purpose of this study is to determine the most effective type of heterogeneous catalyst such as natural zeolite (ZA), Zr-natural zeolite (Zr/ZA) and zeolite Y (H/ZY) in esterification of α-pinene. α-terpinyl acetate was successfully synthesized from α-pinene and acetic anhydride by their heterogeneous catalysts. The esterification reaction was carried out with reaction time, temperature and zeolite catalysts. The most effective catalysts used in the synthesis of α-terpinyl acetate is catalyst H/ZY with the yield is 52.83% at 40oC for the time 4 h with a selectivity of 61.38%. The results showed that the effective separation of catalyst could contribute to developing a new strategy for the synthesis of α-terpinyl acetate.
Simple Plug-In Synthetic Step for the Synthesis of (?)-Camphor from Renewable Starting Materials
Calderini, Elia,Drienovská, Ivana,Myrtollari, Kamela,Pressnig, Michaela,Sieber, Volker,Schwab, Helmut,Hofer, Michael,Kourist, Robert
, p. 2951 - 2956 (2021/06/18)
Racemic camphor and isoborneol are readily available as industrial side products, whereas (1R)-camphor is available from natural sources. Optically pure (1S)-camphor, however, is much more difficult to obtain. The synthesis of racemic camphor from α-pinene proceeds via an intermediary racemic isobornyl ester, which is then hydrolyzed and oxidized to give camphor. We reasoned that enantioselective hydrolysis of isobornyl esters would give facile access to optically pure isoborneol and camphor isomers, respectively. While screening of a set of commercial lipases and esterases in the kinetic resolution of racemic monoterpenols did not lead to the identification of any enantioselective enzymes, the cephalosporin Esterase B from Burkholderia gladioli (EstB) and Esterase C (EstC) from Rhodococcus rhodochrous showed outstanding enantioselectivity (E>100) towards the butyryl esters of isoborneol, borneol and fenchol. The enantioselectivity was higher with increasing chain length of the acyl moiety of the substrate. The kinetic resolution of isobornyl butyrate can be easily integrated into the production of camphor from α-pinene and thus allows the facile synthesis of optically pure monoterpenols from a renewable side-product.
Method for synthesizing isobornyl acetate by camphene
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Page/Page column 5-13, (2018/12/13)
The invention discloses a method for synthesizing isobornyl acetate by camphene. The method comprises the following steps of adding camphene, glacial acetic acid, a main catalyst (hydroxycarboxylic acid) and an additive into a reaction kettle according to a mass ratio of 100:(20 to 400):(1 to 50):(1 to 20), starting to stir, controlling the temperature to 40 to 100 DEG C, and reacting for 2 to 24h, so as to obtain a synthesized product; adding a small amount of water into the synthesized product, standing and delaminating, wherein the upper oil layer is a target product containing isobornyl acetate, the lower layer is acid water containing the catalyst and acetic acid, and the acid water is dewatered and recycled; adding the target product into a water washing tank, adding alkaline water to neutralize, and then adding water to wash, so as to obtain a crude product of the isobornyl acetate; relieving pressure and distilling, so as to obtain the refined isobornyl acetate. The method forsynthesizing the isobornyl acetate by catalyzing the camphene has the advantages that the obtained product has high yield and high purity, and is easy to separate; the used catalyst has high catalyzing activity; the preparation is simple, the repeatability is good, the toxicity is avoided, the corrosion property is low, the isobornyl acetate belongs to regeneration resources, and the industrialization product is easy.