1273-97-8Relevant articles and documents
Stereo- and enantioselectivity in catalytic hydrogenolysis of chiral substituted ferrocenes to give cyclopentanes
Sokolov, V. I.,Troitskaya, L. L.,Khrushcheva, N. S.,Reutov, O. A.
, p. 227 - 234 (1989)
The catalytic hydrogenolysis of 1,2-disubstituted ferrocenes having planar chirality and functional groups such as carboxyl (including ester) or tertiary amino proceeds under mild conditions (1 atm of H2, Pd/C, CF3COOH, 50 deg C) with the retention of fun
The reactions of acylferrocenes with samarium diiodide: Reduction, deoxygenation, reductive coupling and rearrangement
Jong, Shean-Jeng,Fang, Jim-Min,Lin, Chun-Hsu
, p. 42 - 45 (1999)
Acylferrocenes reacted with samarium diiodide in the presence of water to give the corresponding (α-hydroxyalkyl)ferrocenes or alkylferrocenes depending on the reaction time and temperature. On treatment with samarium diiodide in the absence of water, ferrocenecarbaldehyde underwent a reductive coupling to give pinacols, whereas acetylferrocene yielded 3,3-diferrocenyl-2-butanone and 2,3-diferrocenyl-2-butene via the subsequent rearrangement and deoxygenation.
Ionic hydrogenation of acylferrocenes using zinc borohydride: An efficient, mild method for the preparation of alkylferrocenes
Bhattacharyya, Sukanta
, p. 1065 - 1066 (1996)
An effective mild procedure for the reductive deoxygenation of α-ferrocenyl aldehydes, ketones, and alcohols into the corresponding alkylferrocenes is described using a combination of zinc borohydride and zinc chloride. This is the first example of such reactivity of zinc borohydride. The present method allows the synthesis of alkylferrocenes bearing terminally functionalized pendant chains.
Preparation method of diethylferroene with purity being greater than 99%
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Paragraph 0037; 0038; 0039, (2019/12/25)
The invention relates to a preparation method of diethylferroene with purity being greater than 99%. The preparation method comprises the steps that high-content diacetylferrocene crude products are synthesized through an acylation technology firstly; a recrystallization and column separation series-connection method is utilized to separate the synthesized crude products, and thus high-content diacetylferrocene intermediates are obtained; and then the intermediates are reduced through a reduction catalyst and separated and purified, and thus the high-purity diethylferroene is obtained. The preparation method has the beneficial effects that 1, the purity of the intermediate diacetylferrocene with the large polarity difference is increased to be greater than 99% through a chromatographic column purification method, and the fact is the key for obtaining the high-purity target product; and 2, a high-purity borane-methyl sulfide complex with the extremely-high catalytic efficiency is selected, compared with an amalgam reduction method, the synthesis condition is mild, post-treatment is easy, and environmental protection is achieved.
One-pot synthesis of 1,1′-bis(2-amino)ethyl-substituted ferrocenes from the reaction of spiro[2.4]hepta-4,6-diene with lithium amides: An expedient route into functionalized ferrocenophanes
Joly, Kevin M.,Kariuki, Benson M.,Coe, Diane M.,Cox, Liam R.
, p. 358 - 366 (2008/10/09)
The reaction of lithium amides with spiro[2.4]hepta-4,6-diene 2 affords the corresponding (2-aminoethyl)CpLi cyclopropane-ring-opened product that can be trapped in situ with FeCl2 to provide a direct route into 1,1′-bis-aminoethyl ferrocenes 3. In addition to the desired bis-amine products, a number of interesting ferrocene byproducts have been identified. Their formation can be attributed to the associated Bronsted basicity of the lithium amide nucleophiles and their ability to participate in SET processes, opening-up alternative reaction pathways. The desired aminoethyl-substituted ferrocene products are derived primarily from direct nucleophilic cyclopropane ring-opening rather than via amidolithiation of vinylCp intermediates.
