13234-79-2

Basic information

• Product Name: [1,1'-biphenyl]-2-carboxamide
• Synonyms: [1,1'-biphenyl]-2-carboxamide;Einecs 236-206-4;2-Biphenylcarboxamide
• CAS NO: 13234-79-2
• Molecular Formula: C₁₃H₁₁NO
• Molecular Weight: 197.23254
• EINECS: 236-206-4
• Mol File: 13234-79-2.mol
• Article Data: 12

Chemical Properties

• Melting Point: 179-180℃
• Appearance: /
• CAS DataBase Reference: [1,1'-biphenyl]-2-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: [1,1'-biphenyl]-2-carboxamide(13234-79-2)
• EPA Substance Registry System: [1,1'-biphenyl]-2-carboxamide(13234-79-2)

Safety Data

• Hazardous Substances Data: 13234-79-2(Hazardous Substances Data)

Usage

Uses

2-Phenylbenzamide is a derivative of benzamide, a building block compound of various pharmaceutical goods ranging from analgesics to antipsychotics.

Upstream product

• 90128-01-1 2-chloro-7-phenyltropone 
• 591-50-4 iodobenzene 
• 88-67-5 2-Iodobenzoic acid 
• 486-25-9 9-fluorenone 
• 108-88-3 toluene 
• 7664-41-7 ammonia 
• 4001-73-4 2-Bromobenzamide 
• 98-80-6 phenylboronic acid 
• 1088187-91-0 N-(quinolin-8-yl)-[1,1′-biphenyl]-2-carboxamide 
• 100-47-0 benzonitrile 
• 172732-52-4 o-cyanophenylboronic acid-1,3-propylene glycol ester 
• 24973-49-7 biphenyl-2-carbonitrile 
• 138642-62-3 2-Cyanophenylboronic acid 
• 92-52-4 biphenyl 

Downstream Products

• 88413-32-5 N-(Cyclohexylidenemethyl)-o-phenylbenzamide 
• 486-25-9 9-fluorenone 
• 188425-85-6 boscalid 
• 1204-44-0 2-(4-chlorophenyl)aniline 
• 1985-32-6 2-phenylbenzophenone 
• 88413-47-2 Cyclohexanespiro-5'-(2'-o-biphenylylthiazoline) 
• 88413-40-5 N-(Cyclohexylidenemethyl)-o-phenylthiobenzamide 
• 1015-89-0 6(5H)-phenanthridinone 
• 947-84-2 2-Biphenylcarboxylic acid 
• 90-41-5 2-phenylaniline 
• 115293-11-3 N,N'-bis(o-phenylphenyl)formamidine 

Relevant articles and documents

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Selective Removal of Aminoquinoline Auxiliary by IBX Oxidation

8-Aminoquinoline (AQ) is a widely used bidentate auxiliary in metal-catalyzed directed C-H functionalization reactions. Herein, we report an efficient and chemoselective method to convert various N-quinolyl carboxamides to primary amides with the treatment of a stoichiometric amount of 2-iodoxybenzoic acid oxidant or the combination of a catalytic amount of 2-iodobenzoic acid and Oxone co-oxidant in mixed solvents of H2O and HFIP. Its unique compatibility with the Phth-protected α-amino acid (αAA) substrates enhances the overall synthetic utility of the AQ-directed palladium-catalyzed C-H functionalization strategy for synthesis of complex αAAs.

Rh(III)-Catalyzed Redox-Neutral Annulation of Primary Benzamides with Diazo Compounds: Approach to Isoquinolinones

Reported herein is a Rh-catalyzed redox-neutral annulation of primary benzamides with diazo compounds, representing an efficient and economic protocol to isoquinolinones. The procedure exhibited good functional group tolerability, scalability, and regioselectivity, obviating the need for oxidants, and only environmentally benign N2 and H2O were released. Further utilization of the method provided an alternative route to functionalized isoquinolines.