1339838-72-0

Basic information

• Product Name: 1-(4'-fluorophenyl)-4,4,4-trifluoro-1-butanone
• Synonyms: 1-(4'-fluorophenyl)-4,4,4-trifluoro-1-butanone
• CAS NO: 1339838-72-0
• Molecular Weight: 220.167
• Mol File: 1339838-72-0.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 1-(4'-fluorophenyl)-4,4,4-trifluoro-1-butanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4'-fluorophenyl)-4,4,4-trifluoro-1-butanone(1339838-72-0)
• EPA Substance Registry System: 1-(4'-fluorophenyl)-4,4,4-trifluoro-1-butanone(1339838-72-0)

Safety Data

• Hazardous Substances Data: 1339838-72-0(Hazardous Substances Data)

Upstream product

• 692-51-3 (E)-trimethyl(3,3,3-trifluoroprop-1-en-1-yl)silane 
• 459-57-4 4-fluorobenzaldehyde 
• 353-83-3 1,1,1-trifluoro-2-iodoethane 
• 147164-48-5 1-(4-fluorophenyl)ethenyl acetate 
• 34837-84-8 4-fluorobenzeneacetic acid methyl ester 
• 50415-66-2 methyl 2-(4-fluorophenyl)acrylate 
• 71783-52-3 2-(4-fluorophenyl)acrylic acid 
• 405-99-2 para-fluorostyrene 
• 2314-97-8 iodotrifluoromethane 
• 3798-61-6 1-(4-fluorophenyl)prop-2-yn-1-ol 
• 887144-97-0 Togni's reagent 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 1186338-51-1 (2,2-difluorocyclopropyl)(4-fluorophenyl)methanone 
• 51594-59-3 1-(4-fluorophenyl)-2-propen-1-one 

Relevant articles and documents

Synthesis of β-Trifluoromethylated Ketones from Propargylic Alcohols by Visible Light Photoredox Catalysis

Regioselective trifluoromethylation at a remote position represents an important challenge in the development of biologically active molecules and functional materials. A practical method to access β-trifluoromethyl ketones from readily available propargylic alcohols by visible light photocatalysis has been developed. Trifluoromethylation of propargylic alcohols with CF3I in the presence of Ru(bpy)3Cl2 as the photocatalyst followed by double-bond migration/keto-enol tautomerization provides β-trifluoromethyl ketones as the final product. β-Trifluoromethyl ketones are synthesized from readily available propargylic alcohols by visible light photocatalysis. Trifluoromethylation followed by double-bond migration/keto-enol tautomerization provides β-trifluoromethyl ketones as the final product.

Base-Promoted Double-Bond-Migration/Hydrolysis/Isomerization of 4-Aryl-1,1,1-trifluorobut-2-en-2-yl Trifluoromethanesulfonates: A Metal-Free Approach to β-Trifluoromethyl Ketones

A method for the synthesis of β-trifluoromethyl ketones promoted by a base is described. In the presence of DBU, 1-aryl-4,4,4-trifluoromethylbutanones with various functional groups were obtained through the reaction of 4-aryl-1,1,1-trifluorobut-2-en-2-yl

Free-Radical-Promoted Copper-Catalyzed Decarboxylative Alkylation of α,β-Unsaturated Carboxylic Acids with ICH2CF3 and Its Analogues

A novel and efficient free-radical-promoted copper-catalyzed decarboxylative alkylation of α,β-unsaturated carboxylic acids with ICH2CF3 and its analogues has been developed. This methodology provides a convenient access to the synthesis of allylic trifluoromethyl and β-CF3 ketone containing compounds as well as other biologically useful fluorinated molecules and materials.