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Usage

Uses

Used in Organic Chemistry:
Ethanone, 1-[2-(benzoyloxy)-4,6-bis(phenylmethoxy)phenyl]-, is used as a synthetic intermediate for the development of novel organic compounds. Its unique structure and reactivity make it a valuable building block in the synthesis of complex organic molecules, potentially leading to advancements in various chemical applications.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Ethanone, 1-[2-(benzoyloxy)-4,6-bis(phenylmethoxy)phenyl]-, is used as a potential active pharmaceutical ingredient (API) or a precursor in the synthesis of new drugs. Its complex structure may offer unique pharmacological properties, such as selectivity for specific biological targets or improved pharmacokinetic profiles, contributing to the development of innovative therapeutic agents.
Used in Materials Science:
Ethanone, 1-[2-(benzoyloxy)-4,6-bis(phenylmethoxy)phenyl]-, is utilized in materials science for the development of new materials with specific properties. Its molecular structure may contribute to the creation of materials with tailored characteristics, such as improved stability, enhanced reactivity, or unique optical, electronic, or mechanical properties, depending on the application.
Further research is essential to fully understand the potential applications and benefits of Ethanone, 1-[2-(benzoyloxy)-4,6-bis(phenylmethoxy)phenyl]-, in these industries and to explore additional uses that may arise from its unique chemical properties.

Upstream product

• 108-73-6 3,5-dihydroxyphenol 
• 480-66-0 2,4,6-trihydroxyacetophenone 
• 18065-05-9 1-[2,4-bis(benzyloxy)-6-hydroxyphenyl]ethanone 
• 65-85-0 benzoic acid 
• 100-39-0 benzyl bromide 
• 480-40-0 5,7-dihydroxy-2-phenyl-chromen-4-one 
• 137790-18-2 5,7-bis(benzyloxy)-2-phenyl-4H-chromen-4-one 
• 98-88-4 benzoyl chloride 

Downstream Products

• 40489-17-6 2-hydroxypinocembrin 
• 28368-57-2 chrysin-6-C-glucopyranoside 
• 160880-89-7 8-(β-D-glucopyranosyl)-5,7-dihydroxyflavone 
• 548-83-4 galangin 
• 110506-85-9 7-(benzyloxy)-5-hydroxy-2-phenyl-4H-chromen-4-one 

Relevant academic research and scientific papers

Synthesis and Biological Evaluation of 4-Substituted Kaempfer-3-ols

The synthesis of two series of five kaempfer-3-ols was described. The first set all have a C-3 hydroxyl group and the second has a carboxymethoxy ether at the C-3 position. Both series have variable substitution at the C-4 position (i.e., OH, Cl, F, H, OMe). Both kaempferols and carboxymethoxy ethers were evaluated for their ability to inhibit ribosomal s6 kinase (RSK) activity and cancer cell proliferation.

Biosynthesis of natural and novel C-glycosylflavones utilising recombinant Oryza sativa C-glycosyltransferase (OsCGT) and Desmodium incanum root proteins

The rice C-glycosyltransferase (OsCGT) is one of only a small number of characterised plant C-glycosyltransferases (CGT) known. The enzyme C-glucosylates a 2-hydroxyflavanone substrate with UDP-glucose as the sugar donor to produce C-glucosyl-2-hydroxyflavanones. We tested substrate specificity of the enzyme, using synthetic 2-hydroxyflavanones, and showed it has the potential to generate known natural CGFs that have been isolated from rice and also other plants. In addition, we synthesised novel, unnatural 2-hydroxyflavanone substrates to test the B-ring chemical space of substrate accepted by the OsCGT and demonstrated the OsCGT capacity as a synthetic reagent to generate significant quantities of known and novel CGFs. Many B-ring analogues are tolerated within a confined steric limit. Finally the OsCGT was used to generate novel mono-C-glucosyl-2-hydroxyflavanones as putative biosynthetic intermediates to examine the potential of Desmodium incanum biosynthetic CGTs to produce novel di-C-glycosylflavones, compounds implicated in the allelopathic biological activity of Desmodium against parasitic weeds from the Striga genus.

Isotopic labelling of quercetin 3-glucoside

The potentially important dietary antioxidant, quercetin 3-O-β-d-glucoside, has been 13C-labelled at C-2 of the flavonoid unit by synthesis in 15% yield over five steps from [13C]carbon dioxide. The route is appropriate for radiochemical synthesis. Formation of the protected 3-glucosylated flavonol appears to result from [1,7]-sigmatropic rearrangement with migration of a benzyl group followed by cyclisation. A free 5-OH results even when a phosphazene superbase is used.