1671-49-4Relevant articles and documents
Selective synthesis of sulfoxides and sulfonesviacontrollable oxidation of sulfides withN-fluorobenzenesulfonimide
Cao, Zhong-Yan,Li, Xiaolong,Lu, Hao,Wang, Panpan,Wang, Shengqiang,Xu, Xiaobo,Yan, Leyu,Yang, A-Xiu
supporting information, p. 8691 - 8695 (2021/10/22)
A practical and mild method for the switchable synthesis of sulfoxides or sulfonesviaselective oxidation of sulfides using cheapN-fluorobenzenesulfonimide (NFSI) as the oxidant has been developed. These highly chemoselective transformations were simply achieved by varying the NFSI loading with H2O as the green solvent and oxygen source without any additives. The good functional group tolerance makes the strategy valuable.
Method for synthesizing aromatic nitro compound by microchannel reactor
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Paragraph 0034-0062, (2021/06/02)
The invention discloses a method for synthesizing an aromatic nitro compound by a microchannel reactor. The method comprises the following steps: continuously conveying p-methylsulfonyl toluene, sulfuric acid and nitric acid as raw materials into the microchannel reactor for reaction. The micro-channel reactor is used for preparing 2-nitro-4-sulfonyl methyl toluene, the high specific area of the micro-channel reactor can realize rapid heat transfer and keep constant temperature, reaction materials react rapidly during instant mixing, heat can be conducted out in time, local overheating is eliminated, the production risk is reduced, and the production efficiency is greatly improved.
Method for preparing 2-nitro-4-methylsulfonyltoluene by continuous flow
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Paragraph 0030-0035; 0039-0044, (2019/10/17)
The invention discloses a method for preparing 2-nitro-4-methylsulfonyltoluene by continuous flow. The method comprises conveying 1-methyl-4-(methylsulfonyl)-benzene, sulfuric acid and nitric acid continuously into a channel reactor, and allowing to react so as to continuously prepare 2-nitro-4-methylsulfonyltoluene, wherein the channel reactor comprises a cooling module, a fluid module and an outlet module which are communicated in sequence. The method of the invention has the advantages of high safety, low byproduct output, high product purity and the like, and also has the advantages of good process simplicity, good operational convenience, high automation level, high preparation efficiency and the like; the method of the invention is suitable for large-scale continuous preparation of 2-nitro-4-methylsulfonyltoluene and has good application value and application prospect.