1709-60-0

Upstream product

• 104-94-9 4-methoxy-aniline 
• 100-66-3 methoxybenzene 
• 98-68-0 4-methoxy-phenyl-sulphonyl chloride 
• 3112-80-9 bis(p-anisyl)sulfone 
• 110-91-8 morpholine 
• 972-48-5 1-(2,4-dinitro-benzenesulfonyl)-4-methoxy-benzene 
• 7664-93-9 sulfuric acid 
• 7647-01-0 hydrogenchloride 
• 4346-59-2 para-methoxyphenyldiazonium chloride 
• 7782-99-2 sulphurous acid 
• 1879-16-9 1-methoxy-4-methylsulfanyl-benzene 
• 124-38-9 carbon dioxide 
• 1129-26-6 4-methoxybenzene sulfonamide 
• 100-52-7 benzaldehyde 

Downstream Products

• 96636-48-5 S-(4-chlorophenyl) 4-methoxybenzenesulfonothioate 
• 90455-55-3 3-(4-Methoxy-benzenesulfonyl)-1-phenyl-pyrrolidine-2,5-dione 
• 13165-83-8 ethyl p-methoxybenzenesulphinate 
• 5335-87-5 4,4'-dimethoxyphenyl disulfide 
• 95914-29-7 1-(4-methoxyphenyl)-2-phenyldisulfane 
• 882-33-7 diphenyldisulfane 
• 37643-55-3 N-<(4-methoxyphenylsulfonyl)methyl>formamide 
• 27886-81-3 2-(1,3-dithiolan-2-yl)-1-(4-methoxyphenyl)ethan-1-one 
• 55977-43-0 2-hydroxy-4-(4-methoxy-benzenesulfonyl)-3-phenyl-cyclobut-2-enone 
• 1942-34-3 (1R,2S,5R)-(-)-menthyl (S)-4-methoxyphenylsulfinate 
• 97218-22-9 4-(naphthalen-1-ylsulfonyl)phenol 
• 1160295-39-5 C₁₆H₁₈O₄S 
• 116757-20-1 3-<(4-methoxyphenyl)thio>indole 
• 41024-54-8 2-(4-methoxyphenylsulfonyl)-1-phenylethanone 

Relevant academic research and scientific papers

Photoredox Catalyzed Sulfonylation of Multisubstituted Allenes with Ru(bpy)3Cl2 or Rhodamine B

A highly regio- and stereoselective sulfonylation of allenes was developed that provided direct access to α, β-substituted unsaturated sulfone. By means of visible-light photoredox catalysis, the free radicals produced by p-toluenesulfonic acid reacted with multisubstituted allenes to obtain Markovnikov-type vinyl sulfones with Ru(bpy)3Cl2 or Rhodamine B as photocatalyst. The yield of this reaction could reach up to 91%. A series of unsaturated sulfones would be used for further transformation to some valuable compounds.

tert-Butyl Hydroperoxide-Initiated Radical Cyclization of 1-(Allyloxy)-2-(1-Arylvinyl)Benzenes with Sulfinic Acids to Access Sulfonated Benzoxepines

A tert-butyl hydroperoxide-initiated radical cyclization of 1-(allyloxy)-2-(1-arylvinyl)benzenes with sulfinic acids for the construction of sulfonated benzoxepines is developed. This reaction involves a radical pathway and offers a straightforward route to the formation of seven-membered ring via sulfonylation/cyclization process. This methodology features mild reaction conditions, a broad substrate scope and good functional group tolerance. (Figure presented.).

Tert-Butyl Nitrite Promoted Oxidative Intermolecular Sulfonamination of Alkynes to Synthesize Substituted Sulfonyl Pyrroles from the Alkynylamines and Sulfinic Acids

tert-Butyl nitrite promoted oxidative intermolecular sulfonamination of alkynes to synthesize substituted sulfonyl pyrroles from the alkynylamines and sulfinic acids via tandem addition/cyclization was developed. This reaction is performed well by employing tert-butyl nitrite as the oxidant, and various substituted sulfonyl pyrroles are formed in moderate to good yields with no requirement of metal catalysis.

Visible-Light Photocatalytic Bicyclization of 1,7-Enynes toward Functionalized Sulfone-Containing Benzo[a]fluoren-5-ones

A new visible-light photocatalytic arylsulfonylation and bicyclization of C(sp3)-tethered 1,7-enynes with sulfinic acids has been developed, delivering functionalized sulfone-containing benzo[a]fluoren-5-ones with generally good yields. This Eosin Y-catalyzed approach makes use of visible light as a safe and eco-friendly energy source to drive cascade cyclization reactions, resulting in continuous multiple bond-forming events including C–S and C–C bonds to efficiently construct polycyclic-linked alkyl aryl sulfones. (Figure presented.).

Direct Irradiaton of Aryl Sulfides: Homolytic Fragmentation and Sensitized S-Oxidation

The direct irradiation of diphenyl sulfide and p-substituted thioanisoles in the presence of oxygen was investigated by means of both steady state and laser flash photolysis experiments. Two competitive pathways took place from the triplet excited state o

One-step synthesis of racemic α-amino acids from aldehydes, amine components, and gaseous CO2 by the aid of a bismetal reagent

α-Amino acids are essential resources for human life and are highly useful as building blocks for organic synthesis. The core framework of an α-amino acid can be divided into three basic components: an aldehyde, an amine, and carbon dioxide (CO2). We report herein that a one-step synthesis of α-amino acids has been successfully achieved from these three basic and inexpensive chemicals with a single operation, in which the mixture of an aldehyde, a sulfonamide, and gaseous CO2 was heated at 100 °C in the presence of Bu3Sn-SnBu3 and CsF. In this one-pot sequential protocol, two important intermediates (imine and α-amino stannane) are involved and the stannyl anion generated in situ plays a crucial role, particularly for the efficient stannylation of the imine in the presence of proton sources and for promoting retrostannylation of the undesired α-alkoxy stannane owing to its high stability and tolerance of the presence of proton sources. This methodology enabled the synthesis of a wide range of racemic arylglycine derivatives in high yields. Go retro! α-Amino acids are essential resources for human life and are highly useful as building blocks for organic synthesis. The core framework of an α-amino acid is retrosynthesized to an aldehyde, an amine, and carbon dioxide. A one-step synthesis of α-amin Copyright

Microwave-accelerated Pd-catalyzed desulfitative direct C2-arylation of free (NH)-indoles with arylsulfinic acids

The rapid and efficient direct C2-arylation of free (NH)-indoles with arylsulfinic acids proceeded through a microwave-accelerated palladium-catalyzed desulfitation reaction. By using PdCl2 as a catalyst, silver acetate as an oxidant, and H2SO4 as an additive, arylsulfinic acids with both electron-donating and electron-withdrawing groups underwent desulfitative coupling with an array of free (NH)-indoles, thereby selectively providing C2-arylindoles in good yields. From C2 shining sea: The direct C2-arylation of free (NH)-indoles with arylsulfinic acids proceeded through a Pd-catalyzed desulfitation reaction. In the presence of an oxidant and an additive, 2-arylindoles were selectively afforded in good yields. Copyright

Differentiation of diastereotopic bromine atoms in SN2 reactions of gem-dibromides

A novel directed SN2 reaction of conformationally biased gem-dibromides and an arenesulfinate anion is described. The reaction results in the diastereoselective formation of α-bromosulfones. The selectivity originates from pre-coordination of the nucleophile to a free hydroxyl group in the γ-position.

Palladium-catalyzed desulfitative heck-type reaction of aryl sulfinic acids with alkenes

An efficient protocol has been developed for the desulfitative Heck-type reaction of aryl sulfinic acids with a variety of alkenes in the presence of a catalytic amount of Pd(OAc)2 and inexpensive Cu(OAc)2 as oxidant. This method does not require a ligand or a base, thereby broadening the scope of Pd-catalyzed coupling reactions. Copyright

Synthesis of ketones by palladium-catalysed desulfitative reaction of arylsulfinic acids with nitriles

Palladium-catalysed desulfitative addition of arylsulfinic acids to aryl and alkyl nitriles with 2,2′-bipyridine as a ligand afforded a variety of aryl ketones via hydrolysis of ketimine intermediates.