185067-05-4Relevant articles and documents
An efficient hydrocyanation of α, β-unsaturated diesters with TMSCN catalyzed by MgI2 etherate
Pan, Haokun,Li, Hua,Liu, Huijun,Zhang, Xingxian
, p. 388 - 391 (2019/12/24)
A mild, efficient and highly regioselective addition of trimethylsilyl cyanide (TMSCN) to α,β-unsaturated diesters has been achieved by using MgI2 etherate as catalyst under solvent-free conditions. This protocol provides the corresponding β-cy
Asymmetric cyanation of activated olefins with ethyl cyanoformate catalyzed by a modular titanium catalyst
Wang, Jun,Li, Wei,Liu, Yanling,Chu, Yangyang,Lin, Lili,Liu, Xiaohua,Feng, Xiaoming
supporting information; experimental part, p. 1280 - 1283 (2010/06/15)
"Chemical Equation Presented" Asymmetric cyanation of a class of easily available olefins with a favorable cyanide source ethyl cyanoformate (CNCOOEt) was realized by an interesting modular catalyst. High yields and ee values were obtained for a range of substrates under solvent-free and mild reaction conditions. The products obtained could be easily transformed to the enantioenriched useful intermediates 5,6, and pharmaceutically Important γ-aminobutyric acid 7.
Resolution of 4-phenyl-2-pyrrolidinone: A versatile synthetic intermediate
Zelle
, p. 1023 - 1026 (2007/10/02)
A resolution of 4-phenyl-2-pyrrolidinone is described. The resulting enantiomerically pure pyrrolidinones are exploited as precursor to 3-phenylpyrrolidines and 3-phenyl-γ-amino acids (4-amino-3-phenylbutanoic acid derivatives).
NOVEL HETEROCYCLES BY THE MALONIC ESTER VARIATION OF THE JAPP-KLINGEMANN REACTION
Heckendorn, Roland
, p. 921 - 944 (2007/10/02)
Azocompounds prepared by coupling malonic ester derivatives with diazotized anilines, 3-amino-2-chloropyridine, anthranilic ester or 2-aminobenzophenones are shown to be versatile intermediates for the synthesys of various polyaza-heterocycles.
