1859-71-8

Basic information

• Product Name: N-(2-benzoylphenyl)-4-methylbenzenesulfonamide
• Synonyms: Benzenesulfonamide, N-(2-benzoylphenyl)-4-methyl-; N-(2-Benzoylphenyl)-4-methylbenzenesulfonamide
• CAS NO: 1859-71-8
• Molecular Formula: C₂₀H₁₇NO₃S
• Molecular Weight: 351.4189
• Mol File: 1859-71-8.mol
• Article Data: 29

Chemical Properties

• Boiling Point: 543°C at 760 mmHg
• Flash Point: 282.2°C
• Density: 1.287g/cm³
• Vapor Pressure: 7.45E-12mmHg at 25°C
• Refractive Index: 1.637
• CAS DataBase Reference: N-(2-benzoylphenyl)-4-methylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-benzoylphenyl)-4-methylbenzenesulfonamide(1859-71-8)
• EPA Substance Registry System: N-(2-benzoylphenyl)-4-methylbenzenesulfonamide(1859-71-8)

Safety Data

• Hazardous Substances Data: 1859-71-8(Hazardous Substances Data)

Upstream product

• 591-50-4 iodobenzene 
• 6590-65-4 N-(2-Formyl-phenyl)-4-methyl-benzenesulfonamide 
• 5176-12-5 (2-nitrophenyl)phenylmethanol 
• 340696-10-8 2-(hydroxy(phenyl)methyl)-1-(4-methylphenylsulfonamido)benzene 
• 13209-38-6 (2-aminophenyl)(phenyl)methanol 
• 941-55-9 4-toluenesulfonyl azide 
• 119-61-9 benzophenone 
• 6311-23-5 2-(toluene-4-sulfonylamino)-benzoic acid 
• 71-43-2 benzene 
• 98-59-9 p-toluenesulfonyl chloride 
• 118-92-3 anthranilic acid 
• 42840-02-8 2-(Toluene-4-sulfonylamino)-benzoyl chloride 
• 2835-77-0 (2-aminophenyl)(phenyl)methanone 

Downstream Products

• 462120-57-6 2-(4-aminosulfonylphenyl)-3-phenylindole 
• 462120-51-0 2-N-(4-methylsulfonylbenzoyl)-amide-benzophenone 
• 462120-52-1 2-N-(4-aminosulfonylbenzoyl)-amino-benzophenone 
• 1238252-28-2 N-(2-(3-cyclohexyl-1-hydroxy-1-phenylprop-2-ynyl)phenyl)-4-methylbenzenesulfonamide 
• 1238252-23-7 N-(2-(3-cyclopropyl-1-hydroxy-1-phenylprop-2-yn-1-yl)phenyl)-4-methylbenzenesulfonamide 
• 1238252-25-9 N-(2-(3-cyclopentyl-1-hydroxy-1-phenylprop-2-ynyl)phenyl)-4-methylbenzenesulfonamide 
• 1238252-17-9 N-(2-(1-hydroxy-1-phenylbut-2-ynyl)phenyl)-4-methylbenzenesulfonamide 
• 1238251-77-8 N-(2-(1-hydroxy-1,3-diphenylprop-2-yn-1-yl)phenyl)-4-methylbenzenesulfonamide 
• 1238252-20-4 N-(2-(1-hydroxy-1-phenylhept-2-yn-1-yl)phenyl)-4-methylbenzenesulfonamide 
• 1238251-97-2 N-(2-(1-hydroxy-3-(4-methoxyphenyl)-1-phenylprop-2-ynyl)phenyl)-4-methylbenzenesulfonamide 
• 1238252-11-3 N-(2-(1-hydroxy-1-phenylprop-2-yn-1-yl)phenyl)-4-methylbenzenesulfonamide 
• 1238251-99-4 N-(2-(1-hydroxy-1-phenyl-3-p-tolylprop-2-yn-1-yl)phenyl)-4-methylbenzenesulfonamide 
• 1238252-30-6 6-phenyl-5-tosyl-5,6-dihydroindeno[2,1-b]indole 
• 727416-65-1 3-phenyl-1-(toluene-4-sulfonyl)-1H-indole 

Relevant articles and documents

Synthesis of Azepino[1,2-a]indole-10-amines via [6+1] Annulation of Ynenitriles with Reformatsky Reagent

Lewis acid-catalyzed [6+1] annulation reactions of 2-cyano-1-propargyl- and 2-alkynyl-1-cyanomethyl-indoles with Reformatsky reagent are described. 8-Aryl, 8-alkyl-, 8-hetaryl-, 9-aryl, and 9-alkyl-azepino[1,2-a]indole amines were obtained through a 7-endo-mode cyclization of the β-aminoacrylate intermediates. The antiproliferative activity of the azepino[1,2-a]indoles analogs against the HCT-116 cells were also examined.

Synthesis of Spirobicyclic Pyrazoles by Intramolecular Dipolar Cycloadditions/[1s, 5s] Sigmatropic Rearrangements

The formation of fused pyrazoles via intramolecular 1,3-dipolar cycloadditions of diazo intermediates with pendant alkynes is described. A subsequent thermal [1s, 5s] sigmatropic shift of these pyrazole systems resulted in a ring contraction, forming spirocyclic pyrazoles. The limitations of this rearrangement were explored by changing the substituents on the nonmigrating aromatic ring and by using substrates lacking an aromatic linkage to the propargyl group.

Diastereoselective synthesis of 2,4-substituted tetrahydroquinolines via hf(otf)4-catalyzed substitution/cyclization of 2-aminobenzyl alcohols with styrenes

An efficient and convenient stereoselective synthetic approach to 2,4-substituted 1,2,3,4-tetrahydroquinoline has been developed. This catalytic procedure involves a sequential reaction of 2-aminobenzyl alcohol with styrenes in the presence of Hf(OTf)4 ca