18595-86-3

Basic information

• Product Name: 2-(2-BROMOPHENYL)-4H-3,1-BENZOXAZIN-4-ONE
• Synonyms: 2-(2-BROMOPHENYL)-4H-3,1-BENZOXAZIN-4-ONE
• CAS NO: 18595-86-3
• Molecular Formula: C₁₄H₈BrNO₂
• Molecular Weight: 302.126
• Mol File: 18595-86-3.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(2-BROMOPHENYL)-4H-3,1-BENZOXAZIN-4-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-BROMOPHENYL)-4H-3,1-BENZOXAZIN-4-ONE(18595-86-3)
• EPA Substance Registry System: 2-(2-BROMOPHENYL)-4H-3,1-BENZOXAZIN-4-ONE(18595-86-3)

Safety Data

• Hazardous Substances Data: 18595-86-3(Hazardous Substances Data)

Upstream product

• 88-65-3 2-bromobenzoic-acid 
• 7154-66-7 2-bromobenzoic acid chloride 
• 615-43-0 2-iodophenylamine 
• 201230-82-2 carbon monoxide 
• 304690-59-3 (1H-benzo[d][1,2,3]triazol-1-yl)(2-bromophenyl)methanone 
• 98-88-4 benzoyl chloride 
• 118-92-3 anthranilic acid 
• 1022-46-4 2-phenyl-4H-3,1-benzoxazin-4-one 
• 18600-62-9 2-(2-bromobenzamido)benzoic acid 
• 75541-69-4 2-(2-bromobenzoylamino)benzoic acid methyl ester 
• 83389-21-3 (bromo-2 phenyl)-2 benzothiazine-3,1 thione-4 

Downstream Products

• 1452386-76-3 2-(2-bromophenyl)-3-(phenylamino)quinazolin-4(3H)-one 
• 1370643-32-5 5-phenylindazolo[3,2-b]quinazolin-7(5H)-one 
• 18600-62-9 2-(2-bromobenzamido)benzoic acid 

Relevant articles and documents

Palladium-Catalyzed Carbonylative Sonogashira/Annulation Reaction: Synthesis of Indolo[1,2-b]isoquinolines

A palladium-catalyzed carbonylative Sonogashira/annulation reaction for the synthesis of indolo[1,2-b]isoquinolines has been developed. Tetracyclic 6/5/6/6 indoline skeletons were synthesized in moderate to good yields from easily available 2-bromo-N-(2-i

Silver and Palladium Cocatalyzed Carbonylative Activation of Benzotriazoles to Benzoxazinones under Neutral Conditions

A novel and efficient method for the carbonylative activation of benzotriazoles to benzoxazinones has been developed. By using a silver and palladium bimetallic catalyst system, a broad range of benzotriazoles were transformed into the corresponding benzoxazinones in moderate to good yields with excellent functional group tolerance. Notably, this procedure proceeds under neutral conditions.

Ruthenium(II) Catalyzed Regiospecific C-H/O-H Annulations of Directing Arenes via Weak Coordination

Ruthenium(II) catalyzed oxidative C-H/O-H annulations have been demonstrated using two different directing arenes viz. 2-arylquinolinone and 2-arylbenzoxazinone with internal alkynes. Regiospecific annulations have been observed for both directing arenes via the assistance of weaker carbonyl oxygen in the presence of a stronger nitrogen-directing site. In this substrate-controlled convergent protocol the weaker directing group dictates the annulation path.