19094-48-5

Basic information

• Product Name: 3,5-Diiodobenzoic acid
• Synonyms: 3,5-diiodobenzoate;3,5-diiodo-benzoicaci;3,5-Diiodobenzoic acid;Benzoic acid, 3,5-diiodo-
• CAS NO: 19094-48-5
• Molecular Formula: C₇H₄I₂O₂
• Molecular Weight: 373.91
• Product Categories: pharmacetical;Benzoic acid;Acids & Esters;Iodine Compounds
• Mol File: 19094-48-5.mol
• Article Data: 12

Chemical Properties

• Melting Point: >230°C
• Boiling Point: 424.2 °C at 760 mmHg
• Flash Point: 210.4 °C
• Appearance: /
• Density: 2.559 g/cm³
• Vapor Pressure: 5.93E-08mmHg at 25°C
• Storage Temp.: 2-8°C(protect from light)
• PKA: 3.50±0.10(Predicted)
• Sensitive: Light Sensitive
• CAS DataBase Reference: 3,5-Diiodobenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-Diiodobenzoic acid(19094-48-5)
• EPA Substance Registry System: 3,5-Diiodobenzoic acid(19094-48-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 19094-48-5(Hazardous Substances Data)

Usage

General Description

3,5-Diiodobenzoic acid is a chemical compound with the molecular formula C7H4I2O2. It is a derivative of benzoic acid, with two iodine atoms substituted in the 3 and 5 positions on the benzene ring. 3,5-Diiodobenzoic acid is commonly used in organic synthesis and as a building block for the preparation of various pharmaceuticals, agrochemicals, and dyes. 3,5-Diiodobenzoic acid is known for its high reactivity and is often used as a reagent in the preparation of other organic compounds. It is also used in the manufacturing of certain electronics and materials. Additionally, this compound has been studied for its potential biological activities, including anti-cancer and anti-inflammatory properties.

InChI:InChI=1/C7H4I2O2/c8-5-1-4(7(10)11)2-6(9)3-5/h1-3H,(H,10,11)/p-1

Upstream product

• 2122-61-4 4-amino-3,5-diiodobenzoic acid 
• 102153-73-1 3-amino-5-iodobenzoic acid 
• 609-86-9 2-amino-3,5-diiodobenzoic acid 
• 37960-65-9 potassium anthranilate 
• 540-80-7 tert.-butylnitrite 
• 5326-47-6 2-amino-5-iodobenzoic acid 
• 118-92-3 anthranilic acid 
• 150-13-0 4-amino-benzoic acid 
• 190071-24-0 4-acetylamino-3-iodo-benzoic acid 
• 29289-16-5 N-(2-iodo-4-methylphenyl)acetamide 
• 29289-13-2 2-iodo-4-methylaniline 
• 6313-17-3 3-iodo-5-nitro-benzoic acid 
• 618-84-8 3-amino-5-nitro-benzoic acid 
• 388613-52-3 ethyl 3,5-diiodobenzoate 

Downstream Products

• 42860-25-3 3,5-diiodobenzoyl chloride 
• 53279-79-1 (3,5-diiodophenyl)methanol 
• 14266-19-4 3,5‐diiodobenzoic acid methyl ester 
• 352535-59-2 3,5-bis[1'-O-(2'',3'',4'',6''-tetra-O-acetyl-β-D-glucopyranosyl)prop-3'-ynyl]benzyl alcohol 
• 99710-75-5 [1,1′:3′,1″-terphenyl]-5′-carboxylic acid 
• 1613336-72-3 3,5-diiodo-N-(naphthalen-2-yl)benzamide 
• 1613336-63-2 3,5-diiodo-N-(4-phenoxyphenyl)benzamide 
• 1613336-67-6 N-(4-(4-chlorophenoxy)phenyl)-3,5-diiodobenzamide 
• 1167996-07-7 methyl 3,5-di(carbazol-9-yl)benzoate 
• 1536154-83-2 CZ-III-100 
• 1536154-81-0 C₃₉H₂₈N₄O₃ 
• 1383804-45-2 3,5-di(carbazol-9-yl)benzohydrazide 

Relevant articles and documents

IODINE(III)-MEDIATED RADIOFLUORINATION

A process for fluorination of aromatic compounds employing iodonium ylides and applicable to radiofluorination using 18F is described. Processes, intermediates, reagents and radiolabelled compounds are described.

Chiral oxazoline substituted optically active poly(m-phenylene)s: Synthesis and coupling polymerizations of (S)-4-benzyl-2-(3,5-dihalidephenyl) oxazoline using transition metal catalysts

Optically active poly(m-phenylene)s substituted with chiral oxazoline derivatives have been synthesized by the nickel-catalyzed Yamamoto coupling reaction of optically active (S)-4-benzyl-2-(3,5-dihalidephenyl)oxazoline derivatives (X = Br or I). The structures and chiroptical properties of the polymers were characterized by spectroscopic methods and thermal gravimetric analyses. The polymers showed higher absolute optical specific rotation values than their corresponding monomer, and showed a Cotton effect at transition region of conjugated main chain. The optical activities of the polymers should be attributed to the higher order structure such as helical conformations. Moreover, the helical conformation could be induced by addition of metal salts into polymer solutions. The polymers showed good thermal stabilities, which was attributable to the oxazoline side chains.

A rigid metallohexameric macrocycle composed of endo- and exo-cyclic bisterpyridine-metal complexes

Synthesis of terpyridine-based building blocks has allowed the self-assembly of a nanosized metallomacrocycle with precisely positioned, peripheral metal complexes. Construction of the precursors included the assembly of a heteroleptic bisterpyridine-Ru(ii) complex possessing a diiodoaryl moiety that was subsequently reacted with two equivalents of 4′-ethynyl-2, 2′:6′,2′′-terpyridine via a Pd(0)-catalyzed Sonagashira coupling, to generate the requisite monomer with two, 120°-juxtaposed metal coordination sites. Addition of one equivalent of Fe(ii) to one equivalent of the bisligand afforded the metallocycle with 12 metals [6 internal Fe(ii) ions and 6 external Ru(ii) ions] measuring ca. 7 nm in diameter.