21911-61-5

Usage

Uses

Used in Chemical Synthesis:
2-[methyl(phenyl)amino]acetic acid is used as a building block for the synthesis of various organic compounds. Its unique structure allows for the creation of a wide range of chemical products, making it a valuable component in the field of chemistry.
Used in Biochemical Research:
Due to its potential as a building block, 2-[methyl(phenyl)amino]acetic acid is used in biochemical research to explore its role in the synthesis of complex molecules and its interactions with biological systems. This can lead to a better understanding of its properties and potential applications in the life sciences.

InChI:InChI=1/C9H11NO2/c1-7-4-2-3-5-8(7)10-6-9(11)12/h2-5,10H,6H2,1H3,(H,11,12)

Upstream product

• 7732-18-5 water 
• 127-09-3 sodium acetate 
• 79-11-8 chloroacetic acid 
• 95-53-4 o-toluidine 
• 7647-01-0 hydrogenchloride 
• 74-87-3 methylene chloride 
• 598-21-0 2-Bromoacetyl bromide 
• 69825-49-6 N-(2-methylphenyl)glycine ethyl ester 
• 105-36-2 ethyl bromoacetate 
• 88-72-2 1-methyl-2-nitrobenzene 
• 3926-62-3 sodium monochloroacetic acid 

Downstream Products

• 69825-49-6 N-(2-methylphenyl)glycine ethyl ester 
• 90557-96-3 N-nitroso-N-o-tolyl-glycine 
• 70336-63-9 1,4-bis(2-methylphenyl)piperazine-2,5-dione 
• 95-53-4 o-toluidine 
• 611-21-2 N,2-dimethylaniline 
• 617-07-2 N,N'-bis(2-methylphenyl)urea 
• 64450-25-5 4-[(2-methylphenyl)amino]butan-2-one 
• 5405-13-0 N-benzyl-2-methylaniline 
• 183014-07-5 ethyl 1-(2-methylphenyl)-aziridine-2-carboxylate 
• 87565-00-2 C₁₈H₂₀CuN₂O₄ 

Relevant academic research and scientific papers

Perovskite as Recyclable Photocatalyst for Annulation Reaction of N-Sulfonyl Ketimines

A sustainable and cost-effective manner for the photocatalytic annulation reaction of N-sulfonyl ketimines with N-arylglycines to synthesize imidazolidine-fused sulfamidates (31 examples) by employing CsPbBr3 as a heterogeneous photocatalyst has been developed. The catalyst CsPbBr3 can be simply recovered from the reaction mixture and reused at least five times without an obvious reduction in its photocatalytic reactivity, exhibiting a high catalyst economic feature.

Synthesis, antiproliferative, and antioxidant activities of substituted n-[(1,3,4-oxadiazol-2-yl) methyl] benzamines

Background: Oxadiazole emerged as an important class of heterocyclic compound with diverse biological activities like anticancer, antitubercular, anticonvulsant, anti-tubulin, antimicrobial, anti-inflammatory, antioxidant etc. Objective: The objective of

Synthesis and evaluation of phenyl substituted sydnones as potential DPPH-radical scavengers

A series of phenyl substituted sydnones has been synthesized and their radical-scavenging activity has been studied on DPPH free radical. Out of eighteen compounds screened, nine compounds show interesting activity. A mechanism is presented whereby sydnones scavenge DPPH radical through donating H-atom at 4th-position. Its strong radical-scavenging activity mainly arises from 1, 2, 3-oxadiazolium-5-olate ring. Different substituents and their positions on the phenyl ring differently influence DPPH scavenging activity and therefore, may provide clues to design and develop better free-radical scavenging sydnones with multiple activities.

Microwave-assisted synthesis of N-arylglycines: Improvement of sydnone synthesis

Reactions of anilines with ethyl bromoacetate under microwave irradiation have afforded N-arylglycines that are subsequently converted to their N-nitroso derivatives with a combination of silica chloride or periodic acid, wet SiO2 and sodium nitrite in CH2Cl2 with satisfactory yields. In the final step, the use of 1,3-dibromo-5,5-dimethylhydantoin (DBH) as a new and effective reagent for dehydration of N-nitroso-N-arylglycines to sydnones was successfully examined.

Soluble Polymer-Supported Synthesis of α-Amino Acid Derivatives

A practical and efficient synthesis of N-substituted α-amino acid derivatives on soluble polymer support is described.

One-Pot Synthesis of Substituted Aniline-N,N-diacetic Acids

Substituted aniline-N,N-diacetic acids are synthesized by reaction of substituted anilines with n-butyllithium and sodium chloroacetate in good yields.