1066-30-4

Basic information

• Product Name: Chromic acetate
• Synonyms: Chromium triacetate;CHROME ACETATE;CHROMIUM (III) ACETATE;CHROMIC ACETATE;CHROMIUM ACETATE;Aceticacid,chromium(3+)salt;aceticacid,chromium(3++)salt;chromicacetate(iii)
• CAS NO: 1066-30-4
• Molecular Formula: 3C₂H₃O₂*Cr
• Molecular Weight: 229.13
• EINECS: 213-909-4
• Product Categories: Organic-metal salt;metal acetate salt
• Mol File: 1066-30-4.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 117.1 °C at 760 mmHg
• Flash Point: 40 °C
• Appearance: green/Powder
• Density: 1,28 g/cm3
• Vapor Pressure: 13.9mmHg at 25°C
• Water Solubility: slightly soluble
• CAS DataBase Reference: Chromic acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Chromic acetate(1066-30-4)
• EPA Substance Registry System: Chromic acetate(1066-30-4)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• RIDADR: UN 9101
• Hazardous Substances Data: 1066-30-4(Hazardous Substances Data)

Usage

Chemical Properties

Chromic acetate is a gray-green powder or blue-green pasty mass

Uses

Textile mordant, tanning, polymerization and oxidation catalyst, emulsion hardener.

General Description

A grayish green to bluish green powder. The primary hazard is the threat to the environment. Immediate steps should be taken to limit its spread to the environment. Chromic acetate is used in tanning and in textile dyeing.

Air & Water Reactions

Water soluble.

Reactivity Profile

Chromic acetate gives aqueous solutions that are basic (neutralize acids). These neutralizations generate only a little heat. Neither a strong reducing agent nor oxidizing agent, but can serve as both.

Hazard

Toxic by ingestion.

Health Hazard

INHALATION: Irritating. It can produce ulcerations in the respiratory system, perforation of the nasal septum, pneumonitis and bronchial carcinoma. EYES: Irritation. SKIN: May cause dermatitis to exposed skin. Can produce ulcerations and sensitizing reactions.

Flammability and Explosibility

Nonflammable

Safety Profile

Questionable carcinogen with experimental tumorigenic data. Moderately toxic by intravenous route. Human mutation data reported. See also CHROMIUM COMPOUNDS. When heated to decomposition it emits acrid smoke and irritating fumes.

Potential Exposure

Chromic acetate is used to fix certain textile dyes; to harden photographic emulsions in tanning, and as a catalyst

Shipping

UN3288 Toxic solids, inorganic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.

Incompatibilities

Contact with strong oxidizers may cause fire and explosion hazard

Waste Disposal

Dilute and stir in excess soda ash. Let stand, neutralize liquid and flush to sewer. Dispose of sludge in landfill.

InChI:InChI=1/C2H4O2.Cr/c1-2(3)4;/h1H3,(H,3,4);/p-1

Synthetic route

lead(IV) tetraacetate (546-67-8) → chromium(lll) acetate (1066-30-4)

Conditions	Yield
With chromium sulfate Ausfaellen des geloesten Bleies mit Schwefelwasserstoff, Eindampfen im Vakuum ueber Schwefelsaeure;

acetic anhydride (108-24-7) → chromium(lll) acetate (1066-30-4)

Conditions	Yield
With chromium(VI) oxide; tetrachloromethane
With chromium(III) nitrate

2Cr(3+)*OH(1-)*5CH3CO2(1-)*3H2O=Cr2(OH)(CH3CO2)5*3H2O → Cr(OAc)2OH + chromium(lll) acetate (1066-30-4)

Conditions	Yield
In water
In water

chromyl chloride (14977-61-8) + acetic acid (64-19-7) → chromium(lll) acetate (1066-30-4)

Conditions	Yield
With ammonia In acetic acid byproducts: NH4Cl, acetamide; passing of NH3 into ice-cooled dild. soln. of CrO2Cl2, some hours;;

chromium(VI) oxide → chromium(lll) acetate (1066-30-4)

Conditions	Yield
In acetic anhydride dissoln.; heating up to boiling; cooling down; addn. of CCl4; pptn.;; washing with CCl4; drying at 100 °C;;
With dihydrogen peroxide; acetic acid In acetic acid excess H2O2; refluxing (removal of excess H2O2), spectrophotometry;
In acetic anhydride dissoln.; heating up to boiling; cooling down; addn. of CCl4; pptn.;; washing with CCl4; drying at 100 °C;;

chromium(VI) oxide + acetic anhydride (108-24-7) → chromium(lll) acetate (1066-30-4)

Conditions	Yield
In neat (no solvent) the carboxylic acid anhydride is slowly added to dry CrO3 in a teflon lined steel reactor under N2, in an oil bath is the temp. slowly raised to about 140°C, the temp. is maintained at ca. 100° for ca.8 h, then is cooled to 0°C; a solid is separated by addn. of CCl4, is filtered, washed with CCl4 and dried in vac., elem. anal.;	>80

chromium potassium sulfate dodecahydrate → chromium(lll) acetate (1066-30-4)

Conditions	Yield
With NH3; CH3COOH In water addn. of aq. ammonia to an aq. soln. of chromealum, pptn., filtn., washing with distilled water several times, dissolution in a minium quantity of dilute acetic acid;

chromium(III) sulfate → chromium(lll) acetate (1066-30-4)

Conditions	Yield
With hydrogen sulfide In water react. of chromium(III) sulfate and Pb acetate in aq. soln.; addn. of H2S; pptn.; freeing from H2S by passing CO2 through supernatant soln.; evapn. in vac. over KOH or concd. H2SO4;;
With Pb acetate; H2S In water react. of chromium(III) sulfate and Pb acetate in aq. soln.; addn. of H2S; pptn.; freeing from H2S by passing CO2 through supernatant soln.; evapn. in vac. over KOH or concd. H2SO4;;

chromium chloride hexahydrate → chromium(lll) acetate (1066-30-4)

Conditions	Yield
With CH3COOH In acetic acid byproducts: HCl; reflux until HCl evolution is complete, evapg., reflux with fresh glacial CH3COOH;

Cr(OAc)2OH → chromium(lll) acetate (1066-30-4)

Conditions	Yield
With (CH3CO)2O In acetic anhydride; acetic acid reflux, 4 h; filtration, drying over NaOH; elem. anal.;
With CH3COOH In acetic acid reflux, overnight; filtration, drying over NaOH; elem. anal.;

chromium(III) acetate monohydrate (5990-10-3, 5990-11-4, 14976-80-8, 25013-82-5, 66851-10-3, 151383-46-9) → chromium(lll) acetate (1066-30-4)

Conditions	Yield
With CH3COOH In acetic acid reflux, overnight; filtration, drying over NaOH; elem. anal.;
With (CH3CO)2O In acetic anhydride; acetic acid reflux, 4 h; filtration, drying over NaOH; elem. anal.;

tris[bis(trimethylsilyl)methyl]chromium(III) (53668-83-0) → chromium(lll) acetate (1066-30-4)

Conditions	Yield
With AcOH In acetic acid byproducts: CH2(Si(CH3)3)2;

chromic acid (7738-94-5) + acetic acid (64-19-7) → chromium(lll) acetate (1066-30-4)

Conditions	Yield
With D-glucose In water at 90℃; for 1h; Heating / reflux;

chromium(III) sulfate + acetic acid (64-19-7) → chromium(lll) acetate (1066-30-4)

Conditions	Yield
In water at 80 - 85℃; for 1h; pH=1 - 2; Large scale;

3,5-ditertbutyl salicylic acid (19715-19-6) + chromium(lll) acetate (1066-30-4) → chromium 3,5-di-t-butyl salicylate

Conditions	Yield
With sodium hydroxide In water at 60 - 70℃; for 1h;	90%

4-benzoyloxime-3-methyl-1-(2',4'-dinitrophenyl)-2-pyrazolin-5-one + chromium(lll) acetate (1066-30-4) → [Cr(BMNPPZ)3]

Conditions	Yield
With sodium acetate In ethanol; water oxime was dissolved in EtOH under reflux, hot aq. soln. metal acetate and AcONa was added and refluxed for 1 h; react. mixt. was cooled to room temp., ppt. was filtered, washed with hot water and EtOH and dried in air; elem. anal.;	85%

4-acetyloxime-3-phenyl-1-(2',4'-dinitrophenyl)-2-pyrazolin-5-one + chromium(lll) acetate (1066-30-4) → [Cr(APNPPZ)3]

Conditions	Yield
With sodium acetate In ethanol; water oxime was dissolved in EtOH under reflux, hot aq. soln. metal acetate and AcONa was added and refluxed for 1 h; react. mixt. was cooled to room temp., ppt. was filtered, washed with hot water and EtOH and dried in air; elem. anal.;	81%

4-formyloxime-3-phenyl-1-(2',4'-dinitrophenyl)-2-pyrazolin-5-one + chromium(lll) acetate (1066-30-4) → [Cr(FPNPPZ)3]

Conditions	Yield
With sodium acetate In ethanol; water oxime was dissolved in EtOH under reflux, hot aq. soln. metal acetate and AcONa was added and refluxed for 1 h; react. mixt. was cooled to room temp., ppt. was filtered, washed with hot water and EtOH and dried in air; elem. anal.;	80%

ortho-mercaptophenol (1121-24-0) + water (7732-18-5) + chromium(lll) acetate (1066-30-4) + potassium hydroxide → [K3fac-{CrIII(2-mercaptophenolato)3}(H2O)6]n

Conditions	Yield
In methanol for 1h; Schlenk technique; Inert atmosphere; Reflux;	76%

Na(1+)*C6H5COCHCOC(CH2)CH3(1-) + chromium(lll) acetate (1066-30-4) → Cr(III) (methacroylacetophenonato)3

Conditions	Yield
In water added dropwise with stirring; filtered, washed with water, dried, recrystallized from benzene, elem. anal.;	75%

C35H32N8O10S2 + chromium(lll) acetate (1066-30-4) → C70H52Cr2N16O20S4(6-)*6H(1+)

Conditions	Yield
With hydrogenchloride for 1h; Heating;	73%

N,N'-ethylene bis(1-cyclopropyl-6-fluoro-4-oxo-7-(piperazine-1-yl)quinoline-3-carboxylic acid) dihydrochloride + water (7732-18-5) + chromium(lll) acetate (1066-30-4) → C36H44CrF2N8O6(3+)*3C2H3O2(1-)*5H2O

Conditions	Yield
With sodium hydroxide In ethanol at 35℃; for 15h;	72.91%

chromium(lll) acetate (1066-30-4) + N-(2-pyridyl)methylacrylamid, sodium salt (126660-81-9) → chromium(III), N-(2-pyridyl)methylacrylamid complex (126628-08-8)

Conditions	Yield
In water dropwise addn. of satd. aq. soln. of metal salt to an aq. soln. of Na salt of acrylamid with stirring; filtration of ppt., washing with H2O, drying, recrystn. from DMF; elem. anal.;	72%

C32H26N8O12S3 + chromium(lll) acetate (1066-30-4) → C64H40Cr2N16O24S6(6-)*6H(1+)

Conditions	Yield
With hydrogenchloride for 1h; Heating;	70%

1‐((E)‐(5‐((E)‐(2‐hydroxynaphthalene‐1‐yl)methyleneamino)‐4H‐1,2,3‐triazol‐3‐ylimino)methyl)naphthalene‐2‐ol + chromium(lll) acetate (1066-30-4) → C32H35Cr2N5O14

Conditions	Yield
In N,N-dimethyl-formamide for 2h; Reflux;	70%

oxalic acid hydrazide (996-98-5) + chromium(lll) acetate (1066-30-4) → bis(oxaloylhydrazine)chromium acetate*2H2O

Conditions	Yield
In ethanol; water reaction of aq. soln. of Cr-salt with a hot aq. soln. of ligand in a beaker, warming on a waterbath for 0.5 h at 100°C with stirring; addn. of a small amount of aq. ethanol, pptn., filtn. by suction, washing with water, finally with aq. ethanol, drying at room temp. in a desiccator over anhyd. CaCl2, elem. anal.;	65%

chromium(lll) acetate (1066-30-4) + 2-Hydroxybenzoylhydrazine (936-02-7) → bis(salicyloylhydrazine)chromium acetate*2H2O

Conditions	Yield
In ethanol; water reaction of aq. soln. of Cr-salt with an aq.-ethanolic soln. of ligand in a beaker, warming on a waterbath for 0.5 h at 100°C with stirring; keeping for 5-24 h at room temp., pptn., filtn. by suction, washing with water, finally with aq. ethanol, drying at room temp. in a desiccator over anhyd. CaCl2, elem. anal.;	65%

water (7732-18-5) + chromium(lll) acetate (1066-30-4) + N,N'-bis[1,3-benzodioxol-5-ylmethylene]ethane-1,2-diamine (101732-00-7) → Cr2(N,N'-bis[1,3-benzodioxol-5-ylmethylene]ethane-1,2-diamine)(OH)6(H2O)2

Conditions	Yield
In methanol; water Cr-compd. dissolved in CH3OH-H2O, added to refluxing diamine-compd. in CH3OH (molar ratio Cr-diamine=2:1), refluxed for 2 to 3 h; concentrated, washed with Et2O and petroleum ether, filtered, washed with suitable solvents, dried over anhydrous CaCl2, elem. anal.;	65%

water (7732-18-5) + 2,2'-(((4-methyl-1,2-phenylene)bis(azanylidene))bis(methanylylidene))diphenol + chromium(lll) acetate (1066-30-4) → [Cr(2,2'-(((4-methyl-1,2-phenylene)bis(azanylidene))bis(methanylylidene))diphenol)(H2O)(acetate)]

Conditions	Yield
In N,N-dimethyl-formamide for 3h; Reflux;	61.59%

chromium(lll) acetate (1066-30-4) + N-(3-methyl-1-thiocarbamyl-5-oxo-2-pyrazolin-4-ylene)-N'-(4'-benzothiazole) hydrazine (624746-32-3) → [Cr(N-(3-methyl 1-thiocarbamyl-5-oxo-2-pyrazolin-4-ylene)-N'-(4'-benzothiazole)hydrazine)(OAc)3] (624746-25-4)

Conditions	Yield
In ethanol; water refluxing soln. metal salt in aq. EtOH and soln. ligand in EtOH for 1 h; react. mixt. was cooled, ppt. was filtered, washed with EtOH and benzene, and dried over P4O10; elem. anal.;	61%

malonic acid dihydrazide (3815-86-9) + chromium(lll) acetate (1066-30-4) → bis(malonoylhydrazine)chromium acetate*2H2O

Conditions	Yield
In ethanol; water reaction of aq. soln. of Cr-salt with a hot aq. soln. of ligand in a beaker, warming on a waterbath for 0.5 h at 100°C with stirring; addn. of a small amount of aq. ethanol, pptn., filtn. by suction, washing with water, finally with aq. ethanol, drying at room temp. in a desiccator over anhyd. CaCl2, elem. anal.;	60%

isoniazid (54-85-3) + chromium(lll) acetate (1066-30-4) → Cr(NC5H4CONHNH2)2(CH3COO)2(1+)*CH3COO(1-)*2H2O=Cr(NC5H4CONHNH2)2(CH3COO)3*2H2O

Conditions	Yield
In ethanol; water reaction of aq. soln. of Cr-salt with an aq.-ethanolic soln. of ligand in a beaker, warming on a waterbath for 0.5 h at 100°C with stirring; keeping for 5-24 h at room temp., pptn., filtn. by suction, washing with water, finally with aq. ethanol, drying at room temp. in a desiccator over anhyd. CaCl2, elem. anal.;	60%

oxalic acid hydrazide (996-98-5) + indole-2,3-dione (91-56-5) + chromium(lll) acetate (1066-30-4) → C22H17CrN10O6(2+)*2C2H3O2(1-)

Conditions	Yield
In methanol for 8.5 - 10.5h; Reflux;	60%

chromium(lll) acetate (1066-30-4) + 2,5-hexanedione (110-13-4) + ethylenediamine (107-15-3) → 2C2H3O2(1-)*C18H31CrN4O2(2+)

Conditions	Yield
Stage #1: chromium(lll) acetate; ethylenediamine In methanol for 0.5h; Reflux; Stage #2: 2,5-hexanedione In methanol for 8 - 10h; Reflux;	60%

2,6-diacetylpyridine bis(carbohydrazone) (86018-61-3) + chromium(lll) acetate (1066-30-4) → [Cr(2,6-diacetylpyridine bis(carbohydrazone))(acetato)]

Conditions	Yield
With triethylamine In ethanol slow addn. of hot ethanolic soln. of 2,6-diacetylpyridine bis(carbohydrazone) to hot ethanolic soln. of Cr(OAc)3 with continuous stirring, reflux for 18-20 h at 80-90°C in the presence of Et3N; cooling, pptn., filtration, washing with cold EtOH, drying under vac. over P4O10; elem. anal.;	59%

chromium(lll) acetate (1066-30-4) + benzoic acid hydrazide (613-94-5) → Cr(C6H5CONHNH2)3(3+)*3CH3COO(1-)*2H2O=Cr(C6H5CONHNH2)3(CH3COO)3*2H2O

Conditions	Yield
In ethanol; water reaction of aq. soln. of Cr-salt with an aq.-ethanolic soln. of ligand in a beaker, warming on a waterbath for 0.5 h at 100°C with stirring; keeping for 5-24 h at room temp., pptn., filtn. by suction, washing with water, finally with aq. ethanol, drying at room temp. in a desiccator over anhyd. CaCl2, elem. anal.;	55%

5,10,15,20-tetraphenyl-21H,23H-porphine (917-23-7) + chromium(lll) acetate (1066-30-4) → chromium(III) (acetate)tetraphenylporphyrinate (82025-66-9)

Conditions	Yield
In further solvent(s) mixt. of the phosphine and Cr(III) acetate in phenol heated at reflux for 6 h; cooled, dissolved in CHCl3, washed with warm H2O, passed through Al2O3 column, solvent removed under vac.; elem. anal.;	50%
In benzonitrile (Buchler, J. W., Inorg. Nucl. Chem. Lett., 1972, vol.8, p. 1073); mixt. in benzonitrile refluxed at 468 K for 12 h; mixt. cooled; solvent removed (vac.); residue redissolved in CHCl3; purified by chromy. on Al2O3 (CHCl3 as eluent);	40%
In benzonitrile boiling for 6 h; vac. distillation of the solvent;

5',8-bis(dimethylbiguanyl)luteolin + chromium(lll) acetate (1066-30-4) → C27H33CrN10O10

Conditions	Yield
With sodium hydroxide In ethanol at 60 - 90℃; for 6h; pH=9.5; pH-value; Temperature;	47.36%

6-chloro-pyrimidine-2,4-diyldiamine (156-83-2) + indole-2,3-dione (91-56-5) + chromium(lll) acetate (1066-30-4) → C26H15Cl2CrN10O2(2+)*2C2H3O2(1-)

Conditions	Yield
In methanol for 8 - 10h; Reflux;	45%

chromium(lll) acetate (1066-30-4) + acetylacetone (123-54-6) + naphthalene-1,8-diamine (479-27-6) → C32H31CrN4O2(2+)*2C2H3O2(1-)

Conditions	Yield
In methanol Reflux;	45%

chromium(lll) acetate (1066-30-4) + 7,7',8,8'-tetracyanoquinodimethane (1518-16-7) → Cr(3+)*3C6H4(C(CN)2)2(1-)=Cr(C6H4(C(CN)2)2)3

Conditions	Yield
In acetic acid Electrolysis; 408 h;	41%

5,10,15,20-tetraphenyl-21H,23H-porphine (917-23-7) + chromium(lll) acetate (1066-30-4) → (acetato)chromium(III)tetrephenylporphin

Conditions	Yield
In benzonitrile at 468 K for 12 h; cooled, solvent removed under vac., dissolved in CHCl3, chromd. (Al2O3, CHCl3);	40%

manganese (II) acetate tetrahydrate (6156-78-1) + chromium(lll) acetate (1066-30-4) + benzoic acid (65-85-0) + acetonitrile (75-05-8) → 16C7H5O2(1-)*8HO(1-)*6.9Cr(3+)*1.1Mn(3+)*1.1H2O + 12C7H5O2(1-)*4O(2-)*4Cr(3+)*4Mn(2+)*H2O*3C2H3N

Conditions	Yield
In acetic acid at 150℃; for 15h; High pressure;	A 38.8% B 31.4%

o-hydroxyacetophenone (118-93-4) + chromium(lll) acetate (1066-30-4) → {Cr(OC6H4COCH3)3} (62744-21-2)

Conditions	Yield
In water heating aq. soln. of Cr(CH3CO2)3 and 2-hydroxy-acetophenone for 10 h under reflux to 140 °C, extg. react.-soln. with CHCl3, pptg. with abs. ether after processing the org. phase;; pptn.;	25%

Upstream product

• 546-67-8 lead(IV) tetraacetate 
• 64-19-7 acetic acid 
• 53668-83-0 tris[bis(trimethylsilyl)methyl]chromium(III) 
• 5990-10-3 chromium(III) acetate monohydrate 
• 108-24-7 acetic anhydride 
• 14977-61-8 chromyl chloride 
• 7738-94-5 chromic acid 

Downstream Products

• 110-58-7 n-Pentylamine 
• 110-16-7 maleic acid 
• 1490-36-4 2,2,9,9-tetramethyl-decane-3,8-dione 
• 16473-11-3 bicyclo[3.3.1]nonane-2,6-dione 
• 10349-11-8 3-benzoyl-4-methyl-1,2,5-oxadiazole 
• 107-92-6 butyric acid 
• 65-85-0 benzoic acid 
• 112-05-0 nonanoic acid 
• 13601-11-1 potassium hexacyanochromate(III) 
• 633-68-1 2,3-dibromo-9,10-anthraquinone 
• 99179-65-4 2-ethoxy-6-methoxy-[1,4]benzoquinone 
• 861082-85-1 10-benzyl-1,8-dichloro-anthrone 
• 13723-93-8 2,2-dimethyl-5-oxo-3,5-diphenyl-valeric acid 
• 6307-74-0 2,5-diphenoxy-[1,4]benzoquinone 

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