2555-31-9Relevant academic research and scientific papers
A Facile Synthesis of 4-Aryl-2H-1-benzopyran-2-ones
Ahluwalia, Vinod K.,Singh, Daljeet,Singh, Rishi P.
, p. 869 - 872 (1985)
Reaction of 2-hydroxybenzophenones (1, 3, 7, 8) with ethoxycarbonylmethylenetriphenylphosphorane affords 4-aryl-2H-1-benzopyran-2-ones (2, 4-6) in excellent yields. - Keywords: 4-Aryl-2H-1-benzopyran-2-ones; Ethoxycarbonylmethylenetriphenylphosphorane; Friedel-Crafts reaction; 2-Hydroxybenzophenones; Wittig reaction
Cyclization of aryl 3-aryl propynoates into 4-arylcoumarins catalyzed by cyclometalated Platinum(II) complexes
Zaitceva, Olesia,Bénéteau, Valérie,Ryabukhin, Dmitry S.,Eliseev, Ivan I.,Kinzhalov, Mikhal A.,Louis, Benoit,Vasilyev, Aleksander V.,Pale, Patrick
, (2020/03/05)
Cyclometalated (ppy)PtII complexes (ppy = 2-phenylpyridinato-C2,N) catalyze the intramolecular cyclization of aryl propynoates to form coumarins and benzocoumarins. The complex [(ppy)PtCl(MeCN)] (5 mol %) was the most active and effi
Photoinduced cyclization of alkynoates to coumarins with N-Iodosuccinimide as a free-radical initiator under ambient and metal-free conditions
Wang, Zhihui,Li, Xuezhi,Wang, Lei,Li, Pinhua
, p. 1044 - 1051 (2019/01/25)
An efficient photoinduced strategy for the preparation of coumarins was developed. In the presence of N-iodosuccinimide (NIS) as a free-radical initiator and under LED (380–385 nm) irradiation and metal-free conditions, the reaction of alkynoates underwen
Selectivity Controlled Palladium-Catalyzed Carbonylative Synthesis of Propiolates and Chromenones from Phenols and Alkynes
Zhu, Fengxiang,Wu, Xiao-Feng
supporting information, p. 3422 - 3425 (2018/06/11)
An interesting selectivity-controlled palladium-catalyzed oxidative carbonylation procedure for the synthesis of propiolates and chromenones has been developed. Starting from phenols and alkynes, under slightly different conditions, various propiolates an
Rhodium(I)-Catalyzed Decarbonylative Aerobic Oxidation of Cyclic α-Diketones: A Regioselective Single Carbon Extrusion Strategy
Golime, Gangadhararao,Kim, Hun Young,Oh, Kyungsoo
supporting information, p. 942 - 945 (2018/02/22)
A rhodium-catalyzed decarbonylative aerobic oxidation of cyclic α-diketones has been developed for the first time, where the regioselective formations of α-pyrones and isocoumarins have been achieved. The current decarbonylative aerobic oxidation pathway proceeds via the C-C bond cleavage followed by a C-O bond formation, representing a biomimetic oxidation approach to unsaturated six-membered cyclic lactones. The unique ability of rhodium catalysts to induce the decarbonylative aerobic oxidation opens up a new synthetic toolbox that utilizes the "regioselective single carbon" extrusion strategy.
Synthesis and in vitro evaluation of leishmanicidal activity of 7-hydroxy-4-phenylcoumarin derivatives
Rosa, Isael A.,de Almeida, Letícia,Alves, Karina F.,Marques, Marcos J.,Fregnan, Ant?nio M.,Silva, Claudinei A.,Giacoppo, Juliana O. S.,Ramalho, Teodorico C.,Carvalho, Diogo T.,dos Santos, Marcelo H.
, p. 131 - 139 (2017/01/12)
Eight coumarin derivatives (2–8) were synthesized from 7-hydroxy-4-phenylcoumarin 1 and were evaluated for their in vitro leishmanicidal activity against promastigote and amastigote forms of Leishmania amazonensis, as well their toxicity in murine macroph
Single-step synthesis of 4-phenyl and 3,4-dihydro-4-phenyl coumarins using a recyclable Preyssler heteropolyacid catalyst under solvent-free reaction conditions
Escobar, Anglica M.,Ruiz, Diego M.,Autino, Juan C.,Romanelli, Gustavo P.
, p. 10109 - 10123 (2016/01/12)
4-Phenyl and 3,4-dihydro-4-phenylcoumarins were prepared by direct esterification of phenols with phenylpropiolic and cinnamic acids, respectively, using a compound with Preyssler structure (H14P5NaW30O110) (PA)
Cp?Co(III)-Catalyzed Annulations of 2-Alkenylphenols with CO: Mild Access to Coumarin Derivatives
Liu, Xu-Ge,Zhang, Shang-Shi,Jiang, Chun-Yong,Wu, Jia-Qiang,Li, Qingjiang,Wang, Honggen
supporting information, p. 5404 - 5407 (2015/11/18)
Cp?Co(III)-catalyzed annulations of 2-alkenylphenols with CO for the synthesis of coumarin derivatives have been developed. The reaction features mild reaction conditions, broad substrate scope, and good functional group tolerance. Preliminary mechanistic studies were conducted, suggesting that C-H activation is the turnover limiting step. Furthermore, the efficiency of this reaction was demonstrated by the rapid total synthesis of three natural products herniarin, xanthyletin, and seselin.
Synthesis of 4-arylcoumarins via palladium-catalyzed arylation/cyclization of ortho-hydroxylcinnamates with diaryliodonium salts
Yang, Yang,Han, Jianwei,Wu, Xunshen,Xu, Shujia,Wang, Limin
supporting information, p. 3809 - 3812 (2015/06/08)
The palladium-catalyzed arylation/cyclization of ortho-hydroxylcinnamate ester derivatives by using diaryliodonium(III) salts has been developed. With this method, 4-arylcoumarins were easily prepared in good to excellent yields under base-free conditions
Palladium-catalyzed domino protodecarboxylation/oxidative Heck reaction: Regioselective arylation of coumarin-3-carboxylic acids
Khoobi, Mehdi,Molaverdi, Fatemeh,Alipour, Masoumeh,Jafarpour, Farnaz,Foroumadi, Alireza,Shafiee, Abbas
, p. 11164 - 11168 (2014/01/06)
A protocol for straightforward and step-economical synthesis of neoflavones from coumarin-3-carboxylic acids is developed. This approach enables controlled protodecarboxylation/regioselective C-H arylation of coumain-3-carboxylic acids in one-pot using a
