2621-79-6

Basic information

• Product Name: N-METHYL-N-PHENYLURETHANE
• Synonyms: N-METHYL-N-PHENYLURETHANE;N-METHYL-N-PHENYURETHANE;ETHYL N-METHYL-N-PHENYL-CARBAMATE;Carbanilic acid, N-methyl-, ethyl ester;Ethyl methylphenylcarbamate;N-Methylcarbanilic acid, ethyl ester;N-Methyl-N-phenylurethane, 98+%;Methyl(phenyl)carbamic acid ethyl ester
• CAS NO: 2621-79-6
• Molecular Formula: C₁₀H₁₃NO₂
• Molecular Weight: 179.22
• EINECS: 220-065-0
• Mol File: 2621-79-6.mol
• Article Data: 10

Chemical Properties

• Melting Point: 242-244 °C
• Boiling Point: 243-244 °C(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.074 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.032mmHg at 25°C
• Refractive Index: n20/D 1.515(lit.)
• PKA: 0.25±0.50(Predicted)
• BRN: 2211046
• CAS DataBase Reference: N-METHYL-N-PHENYLURETHANE(CAS DataBase Reference)
• NIST Chemistry Reference: N-METHYL-N-PHENYLURETHANE(2621-79-6)
• EPA Substance Registry System: N-METHYL-N-PHENYLURETHANE(2621-79-6)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-37/39
• RIDADR: 2810
• WGK Germany: 3
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 2621-79-6(Hazardous Substances Data)

Usage

General Description

N-Methyl-N-phenylurethane is a chemical compound with the molecular formula C9H10N2O2. It is colorless, solid, and possesses an aromatic scent. It is used primarily in the manufacture of other chemicals and has few direct applications itself. Somewhat soluble in water, it is miscible with solvents like ethanol and ether. The compound reacts violently with strong oxidants and can produce toxic fumes under certain conditions. Additionally, it can be harmful if ingested, inhaled, or brought into contact with the skin or eyes, warranting careful handling and storage.

InChI:InChI=1/C10H13NO2/c1-3-13-10(12)11(2)9-7-5-4-6-8-9/h4-8H,3H2,1-2H3

Upstream product

• 541-41-3 chloroformic acid ethyl ester 
• 100-61-8 N-methylaniline 
• 60-29-7 diethyl ether 
• 618-40-6 1-Methyl-1-phenylhydrazine 
• 1972-28-7 diethylazodicarboxylate 
• 103-71-9 phenyl isocyanate 
• 36602-08-1 (N-methylanilino)acetonitrile 
• 141-52-6 sodium ethanolate 
• 132431-15-3 2-(N-methylanilino)-2-phenylsulfanylacetonitrile 
• 64-67-5 diethyl sulfate 
• 124-38-9 carbon dioxide 
• 33224-04-3 N-methyl-N-phenyl-2-nitrobenzenesulfenanilide 
• 3741-66-0 Ethyl benzoyl carbonate 
• 101-99-5 N-carboethoxyaniline 

Downstream Products

• 28685-60-1 N-carbomethoxy-N-methylaniline 
• 100-61-8 N-methylaniline 
• 1837-74-7 ethyl N-methylcyclohexylcarbamate 
• 121-69-7 N,N-dimethyl-aniline 
• 14288-22-3 N,N'-dimethyl-N,N'-diphenyl-oxalamide 
• 35472-56-1 N-methyl-anthranilic acid ethyl ester 
• 10541-82-9 ethyl 4-(methylamino)benzoate 
• 611-92-7 1,3-dimethyl-1,3-diphenylurea 
• 80179-76-6 ethyl N-methyl-N-4-nitrophenylcarbamate 
• 4285-42-1 N-phenyl-N-methylcarbamoyl chloride 

Relevant articles and documents

PARG INHIBITORY COMPOUNDS

The present invention relates to compounds of formula I that function as inhibitors of PARG (Poly ADP-ribose glycohydrolase) enzyme activity: wherein R1a, R1b, R1c, R1d, R1e, W, X1, X2, X3, X4, X5, X6, X7, c are each as defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which PARG activity is implicated.

Reduction et photoreduction de derives de l'acide carbonique influence de l'hexamethylphosphorotriamide

Photoreduction and reduction of carbonic acid derivatives in HMPT have been compared.The highest yield of alkane was obtained from N,N-dimethylthiocarbamates either by the photochemical method or by reduction with a dissolved metal.Competitive reactions have been characterized: - during the photoreduction not only the alkane but products of a photo-Fries rearrangement and products of a homolytic cleavage were detected; - basic reactions can compete with the reduction of carbonic acid derivatives by sodium in HMPT.

Process for the production of blocked compounds optionally containing free hydroxyl groups and their use for the production of polyurethanes

The present invention relates to a process for the production of compounds containing reversibly blocked and, optionally, free alcoholic hydroxyl groups, characterized in that organic compounds containing at least one alcoholic hydroxyl group, but otherwise being inert under the reaction conditions are reacted at 0° to 140° C. with N,N'-disubstituted 5-acylimino-imidazolidine diones. The present invention also relates to the use of these compounds for the production of polyurethanes.