26218-40-6

Basic information

• Product Name: 1,2,5-Oxadiazole, 3,4-bis(4-methoxyphenyl)-, 2-oxide
• CAS NO: 26218-40-6
• Molecular Formula: C16H14N2O4
• Molecular Weight: 298.298
• Mol File: 26218-40-6.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 1,2,5-Oxadiazole, 3,4-bis(4-methoxyphenyl)-, 2-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,5-Oxadiazole, 3,4-bis(4-methoxyphenyl)-, 2-oxide(26218-40-6)
• EPA Substance Registry System: 1,2,5-Oxadiazole, 3,4-bis(4-methoxyphenyl)-, 2-oxide(26218-40-6)

Safety Data

• Hazardous Substances Data: 26218-40-6(Hazardous Substances Data)

Upstream product

• 532-31-0 silver benzoate 
• 38435-51-7 N-hydroxy-4-methoxy-benzenecarboximidoyl chloride 
• 3907-06-0 3,3-Dimethylcyclopropen 
• 118-92-3 anthranilic acid 
• 63397-13-7 4,4'-dimethoxy benzil dioxime 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 1226-42-2 1,2-bis(4-methoxyphenyl)-1,2-ethanedione 
• 3717-21-3 p-methoxyl benzaldoxime 
• 56504-51-9 5-(4-methylbenzylidene)barbituric acid 
• 1753-47-5 5-(4-dimethylaminobenzylidene)barbituric acid 
• 49546-71-6 5-(4-methoxybenzylidene)barbituric acid 
• 27402-47-7 5-benzylidenebarbituric acid 
• 119072-55-8 tert-butylisonitrile 
• 74903-79-0 N-hydroxy-4-methoxybenzenecarboximidoyl chloride 

Downstream Products

• 82164-07-6 3-(4-Methoxy-phenyl)-isoxazole-4,5-dicarboxylic acid bis-benzylamide 
• 874-90-8 4-methoxybenzonitrile 
• 82169-96-8 diethyl 3-(4′-methoxyphenyl)isoxazole-4,5-dicarboxylate 
• 83421-59-4 1,4-Dioxan-tetracarbonsaeuremethylester 
• 70416-62-5 5-butyl-3-(4-methoxyphenyl)-2-isoxazoline 

Relevant articles and documents

A fast route for the synthesis of tetrazolyl oximes by a novel multicomponent reaction between Z-chlorooximes, isocyanides and trimethylsilyl azide

A library of twenty variously decorated 1,5-disubstituted-(1H-tetrazol-5-yl)methanone oximes was prepared in one single synthetic step exploiting the combination of (Z)-chlorooximes, isocyanides and trimethylsilyl azide. The formal [3+1] cycloaddition between isocyanides and nitrile N-oxides with respect to the [3+1] cycloaddition between isocyanides and azides prevails, while the direct attack of azide onto nitrile N-oxides remains competitive. Finally, an intramolecular cyclization of a (1H-tetrazol-5-yl)methanone oxime to a benzoisoxazole tetrazole is reported for the first time.

Heterocyclization of 5-(Arylmethylidene)pyrimidine-2,4,6(1H,3H,5H)-triones with Arenecarbaldehyde Oximes in the Presence of N-Bromosuccinimide and Triethylamine

5-(Arylmethylidene)pyrimidine-2,4,6(1H,3H,5H)-triones reacted with substituted benzaldehyde oximes in the presence of N-bromosuccinimide and triethylamine to give 1,4-diaryl-2-oxa-3,7,9-triazaspiro-[4.5]dec-3-ene-6,8,10-triones and 3,4-diaryl-1,2,5-oxadia

Highly regioselective nitrile oxide dipolar cycloadditions with ortho-nitrophenyl alkynes

The dipolar cycloadditions of ortho-nitrophenyl alkynes with aryl nitrile oxides has been demonstrated. A range of substituents are tolerated on the alkyne. These reactions proceed with excellent levels of regioselectivity. Subsequent functionalization of the isoxazole scaffold has been demonstrated.