26709-60-4

Upstream product

• 21370-57-0 methyl 2-methyl-3-phenylacrylate 
• 198547-76-1 3-chloro-2-methyl-1,3-diphenyl-propan-1-one 
• 7647-01-0 hydrogenchloride 
• 100-52-7 benzaldehyde 
• 93-55-0 1-phenyl-propan-1-one 
• 141-52-6 sodium ethanolate 
• 6263-84-9 1,3,5-triphenyl-1,5-pentanedione 
• 108-88-3 toluene 
• 201230-82-2 carbon monoxide 
• 98-80-6 phenylboronic acid 
• 14182-01-5 (2E)-2-methyl-1,3-diphenylprop-2-en-1-one 
• 103-49-1 dibenzylamine 
• 673-32-5 1-Phenylprop-1-yne 
• 61878-73-7 3-hydroxy-2-methyl-1,3-diphenyl-propan-1-one 

Downstream Products

• 41231-80-5 (+/-)-3-hydroxy-2-methyl-1.3-diphenyl-butene-⁽¹⁾ 
• 74272-43-8 1-phenyl-2,3-dimethylindene 
• 857973-57-0 2-methyl-1,3-diphenyl-pentan-1-one 
• 1846-28-2 5-methyl-2,4,6-triphenylpyrimidine 
• 40685-26-5 2-methyl-1,3,3-triphenyl-propan-1-one 
• 14181-91-0 2,3-dibromo-2-methyl-1,3-diphenyl-propan-1-one 
• 140846-03-3 3-Methyl-2,4-diphenyl-1,4-dihydro-benzo[4,5]imidazo[1,2-a]pyrimidine 
• 83909-23-3 4-Methyl-3,5-diphenyl-2-cyclohexen-1-on 
• 4842-43-7 2-methyl-1,3-diphenylpropan-1-one 
• 158630-21-8 3,5-diphenyl-4-methyl-3,4-dihydro-2H-pyrrole-2,2-dicarboxylate de diethyle 
• 861355-95-5 (2-methyl-3-oxo-1,3-diphenyl-propyl)-malonic acid dimethyl ester 
• 78018-66-3 2,4,6-triphenyl-3,5-dimethylpyridine 
• 861330-64-5 (2-methyl-3-oxo-1,3-diphenyl-propyl)-malonic acid 
• 1380077-09-7 (S)-2-amino-5-methyl-4,6-diphenyl-4H-pyran-3-carbonitrile 

Relevant academic research and scientific papers

Palladium-Catalyzed Synthesis of α-Methyl Ketones from Allylic Alcohols and Methanol

One-pot synthesis of α-methyl ketones starting from 1,3-diaryl propenols or 1-aryl propenols and methanol as a C1 source is demonstrated. This one-pot isomerization-methylation is catalyzed by commercially available Pd(OAc)2 with H2O as the only by-product. Mechanistic studies and deuterium labelling experiments indicate the involvement of isomerization of allyl alcohol followed by methylation through a hydrogen-borrowing pathway in these isomerization-methylation reactions.

New photochromic α-methylchalcones are highly photostable, even under singlet oxygen conditions: Breaking the α-methyl michael-system reactivity by reversible peroxybiradical formation

The α-methylated chalcones 7a–7e behave as P-type photochromic substances with photo-stationary states (PSS) as high as 15:85 when irradiated at 350 nm. These compounds are easily accessible in pure E-configuration by aldol condensation or by oxidative co

Manganese(I) catalyzed cross-coupling of secondary allylic alcohols and primary alcohols

Cross-coupling of alcohols to value-added products by using sustainable catalytic reactions has gained attention in recent years. Isomerization of secondary allylic alcohol to the corresponding enolizable ketone is an atom economical and known transformation. Herein, a selective cross-coupling of secondary allylic alcohol and primary alcohol is reported to afford the corresponding α-alkenyl or alkylation products. These catalytic protocols proceed via acceptorless dehydrogenative coupling (ADC) or borrowing hydrogen (BH) strategies, which liberates water and/or hydrogen as the only byproducts. Highly abundant manganese-based pincer catalysts catalyze the reactions.

Substituent-Controlled Divergent Cascade Cycloaddition Reactions of Chalcones and Arylalkynols: Access to Spiroketals and Oxa-Bridged Fused Heterocycles

Herein, we report substituent-controlled divergent cascade cycloaddition reactions of chalcones and arylalkynols in the presence of PtI2. Depending on the substituent on the chalcone, either spiroketals or oxa-bridged fused heterocycles could be obtained in the ranges of 86–97% and 87–95% yields under identical reaction conditions. Control experiments were carried out to elucidate the origin of the high chemoselectivity. These provide a method for the synthesis of a diverse array of structurally complex oxygen-containing heterocycles. (Figure presented.).

N-para-sulfonium salt substituted pyrazoline derivative, photocurable composition and preparation method

The invention relates to an N-para-sulfonium salt substituted pyrazoline derivative shown as the following formula (I) in the specification, a photocurable composition, and a preparation method of theN-para-sulfonium salt substituted pyrazoline derivative shown as the following formula (I). The N-para-sulfonium salt substituted pyrazoline derivative shown as formula (I) has good absorption at a wavelength of 350nm or above, and compared with a 5-substituted sulfonium salt, the N-para-sulfonium salt substituted pyrazoline derivative has the advantages of simpler and more convenient molecule synthesis steps and reduced cost of raw materials, and is more suitable for industrial production and application.

Photoredox β-thiol-α-carbonylation of enones accompanied by unexpected Csp2-C(CO) bond cleavage

An olefinic difunctionalization method of enones was presented hereviaaerobic visible-light catalysis. A novel reactivity was showcased in conjunction with the selective Csp2-C(CO) bond activation of enones, which provided a convenient method for the preparation of various β-thiolated-α-functionalized compounds. Moreover, the preliminary investigation of the mechanism indicated that a β-peroxysulfide intermediate was formed under the promotion of visible light under an oxygen atmosphere, which finally induced the unexpected C-C bond cleavage.

Palladium-Catalyzed Carbonylative Synthesis of α-Branched Enones from Aryl Iodides and Arylallenes

In this communication, an interesting carbonylation protocol for the preparation of α-branched enones has been established. Starting from readily available aryl iodides and allenes, with formic acid as the CO source and reductant, moderate to good yields of the desired enones were isolated. Although it is a carbonylation methodology, the use of a CO source can avoid the manipulation of CO gas directly. Notably, this procedure also presents the first example on carbonylative synthesis of α-branched enones.

Proton-Coupled Electron Transfer: Transition-Metal-Free Selective Reduction of Chalcones and Alkynes Using Xanthate/Formic Acid

Highly chemoselective reduction of α,β-unsaturated ketones to saturated ketones and stereoselective reduction of alkynes to (E)-alkenes has been developed under a transition-metal-free condition using a xanthate/formic acid mixture through proton-coupled electron transfer (PCET). Mechanistic experiments and DFT calculations support the possibility of a concerted proton electron-transfer (CPET) pathway. This Birch-type reduction demonstrates that a small nucleophilic organic molecule can be used as a single electron-transfer (SET) reducing agent with a proper proton source.

Iron-Catalyzed Tandem Three-Component Alkylation: Access to α-Methylated Substituted Ketones

The borrowing hydrogen strategy has been applied in the synthesis of α-branched methylated ketones via a tandem three-component reaction catalyzed by a diaminocyclopentadienone iron tricarbonyl complex. Various alkyl and aromatic methyl ketones underwent dialkylation with various primary alcohols and methanol as alkylating agents in mild reaction conditions and good yields. Deuterium labeling experiments suggested that the benzylic alcohol was the hydrogen source in this tandem process.

Pd-catalyzed synthesis of α,β-unsaturated ketones by carbonylation of vinyl triflates and nonaflates

A general and highly chemoselective Pd-catalyzed protocol for the synthesis of α,β-unsaturated ketones by carbonylation of vinyl triflates and nonaflates is presented. Applying the specific monophosphine ligand cataCXium A, the synthesis of various vinyl ketones as well as carbonylated natural product derivatives proceeds in good yields.