3273-78-7

Basic information

• Product Name: 4,4'-DIAMINO-3,3'-DINITRODIPHENYL ETHER
• Synonyms: 4,4'-DIAMINO-3,3'-DINITRODIPHENYL ETHER;Bis-(4-amino-3-nitrophenyl)-ether;[4-(4-amino-3-nitro-phenoxy)-2-nitro-phenyl]amine;4-(4-amino-3-nitrophenoxy)-2-nitroaniline;4-(4-azanyl-3-nitro-phenoxy)-2-nitro-aniline
• CAS NO: 3273-78-7
• Molecular Formula: C₁₂H₁₀N₄O₅
• Molecular Weight: 290.23
• Mol File: 3273-78-7.mol
• Article Data: 6

Chemical Properties

• Melting Point: 179-180 °C
• Boiling Point: 510.7°Cat760mmHg
• Flash Point: 262.7°C
• Appearance: /
• Density: 1.541g/cm³
• PKA: 0.44±0.10(Predicted)
• CAS DataBase Reference: 4,4'-DIAMINO-3,3'-DINITRODIPHENYL ETHER(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4'-DIAMINO-3,3'-DINITRODIPHENYL ETHER(3273-78-7)
• EPA Substance Registry System: 4,4'-DIAMINO-3,3'-DINITRODIPHENYL ETHER(3273-78-7)

Safety Data

• Hazardous Substances Data: 3273-78-7(Hazardous Substances Data)

Upstream product

• 3070-87-9 N-[4-(4-acetylamino-3-nitrophenoxy)-2-nitrophenyl]acetamide 
• 100-02-7 4-nitro-phenol 
• 824-78-2 4-nitrophenol sodium salt 
• 100-00-5 4-chlorobenzonitrile 
• 15267-98-8 sodium 4-aminophenolate 
• 3070-86-8 N-[4-(4-acetylaminophenoxy)phenyl]acetamide 
• 6149-33-3 4-(4-nitrophenoxy)aniline 
• 103-90-2 4-acetaminophenol 
• 2687-40-3 4-nitrophenyl 4'-acetamidophenyl ether 
• 2687-41-4 N-[4-(4-aminophenoxy)phenyl]acetamide 
• 101-63-3 bis(4-nitrophenyl)ether 
• 101-80-4 4,4'-oxydiphenylene diamine 

Downstream Products

• 75708-90-6 4-amino-4'-hydroxy-3,3'-dinitrodiphenyl ether 
• 47169-38-0 4,4'-dihydroxy-3,3'-dinitrodiphenyl ether 
• 894734-47-5 5,5'-oxy-bis[2-(4'-methoxyphenyl)-1H-benzimidazole] 
• 1403460-70-7 5,5'-oxy-bis[2-(3',5'-dimethoxyphenyl)-1H-benzimidazole] 
• 1403460-71-8 5,5'-oxy-bis[2-(3',4',5'-trimethoxyphenyl)-1H-benzimidazole] 
• 1403460-72-9 5,5'-oxy-bis[2-(3'-methoxy-4'-hydroxyphenyl)-1H-benzimidazole] 
• 1403460-73-0 5,5'-oxy-bis[2-(4'-bromophenyl)-1H-benzimidazole] 
• 1403460-74-1 5,5'-oxy-bis[2-(2',4'-dichlorophenyl)-1H-benzimidazole] 
• 53357-17-8 C₁₄H₁₀N₄OS₂ 
• 15268-07-2 3,3'-diaminodiphenyl ether 
• 2676-59-7 bis(3,4-diaminophenyl)ether 
• 38490-83-4 3,3'-dinitrodiphenyl ether 

Relevant articles and documents

Design of novel bis-benzimidazole derivatives as DNA minor groove binding agents

A new series of bis-benzimidazole derivatives were designed and synthesized. In vitro cytotoxicity evaluation showed that these compounds exhibited high activity against the selected tumor cells. Among them, compound 9 owned the best potential, its IC50 values being 5.95 μmol/L (mononuclear tumor cell line (U937)) and 5.58 μmol/L (cervical cancer cell (HeLa)). Fluorescence and UV-vis studies showed that compound 9 could bind into the minor groove of DNA.

Oppi briefs practical and efficient synthesis of 4,4'-dihydroxy-3,3'- dinitrodiphenyl ether and 1,3-bis(4-hydroxy-3-nitrophenoxy)benzene in aqueous alkaline medium

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Synthesis and structure of Di[methoxy(ethoxy)carbonylamino-1H-benzimidazol- 5-yl] ethers

A procedure was developed for preparing di[methoxy(ethoxy)carbonylamino-1H- benzimidazol-5-yl] ethers by the reaction of methyl or ethyl chloroformate with sodium cyanamide, followed by the reaction of the resulting methyl or ethyl cyanocarbamate with 4-(3,4-diaminophenoxy)-1,2-phenylenediamine in acidic solution. 2005 Pleiades Publishing, Inc.