2683-43-4

Basic information

• Product Name: 2,4-DICHLORO-6-NITROANILINE
• Synonyms: TIMTEC-BB SBB003479;Benzenamine, 2,4-dichloro-6-nitro-;4,6-DICHLORO-2-NITROANILINE;2,4-DICHLORO-6-NITRO-PHENYLAMINE;2,4-DICHLORO-6-NITROANILINE;2,4-DICHLORO-6-NITROBENZENAMINE;2,4-DICHLORO-6-NITROANILINE 99%;2-Nitro-4,6-dichloroaniline
• CAS NO: 2683-43-4
• Molecular Formula: C₆H₄Cl₂N₂O₂
• Molecular Weight: 207.01
• EINECS: 220-241-7
• Product Categories: Amines;C2 to C6;Nitrogen Compounds;Building Blocks;C6;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks
• Mol File: 2683-43-4.mol
• Article Data: 4

Chemical Properties

• Melting Point: 101-103 °C(lit.)
• Boiling Point: 360.98°C (rough estimate)
• Flash Point: 139.8°C
• Appearance: /
• Density: 1.6257 (rough estimate)
• Vapor Pressure: 0.00072mmHg at 25°C
• Refractive Index: 1.6100 (estimate)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility: Chloroform (Slightly), DMSO (Slightly)
• PKA: pK1:-3.00(+1) (25°C)
• BRN: 642902
• CAS DataBase Reference: 2,4-DICHLORO-6-NITROANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DICHLORO-6-NITROANILINE(2683-43-4)
• EPA Substance Registry System: 2,4-DICHLORO-6-NITROANILINE(2683-43-4)

Safety Data

• Hazard Codes: Xn,N,T+
• Statements: 20/21/22-36/37/38-51/53-33-26/27/28
• Safety Statements: 26-37/39-61-45-36/37-28
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 2683-43-4(Hazardous Substances Data)

Usage

Chemical Properties

YELLOW FLUFFY POWDER

Uses

2,4-Dichloro-6-nitroaniline was used to design a faster-reacting, more intensely fluorescent pH probe based on rhodamine spirolactam structure.

InChI:InChI=1/C6H4Cl2N2O2/c7-3-1-4(8)6(9)5(2-3)10(11)12/h1-2H,9H2

Upstream product

• 60-29-7 diethyl ether 
• 59483-70-4 N,N-dichloro-2-nitroaniline 
• 305-80-6 4-diazobenzenesulfonic acid 
• 100-34-5 benzene diazonium chloride 
• 69732-99-6 2,4-dichloro-N-nitro-aniline 
• 64-19-7 acetic acid 
• 88-74-4 2-nitro-aniline 
• 89-63-4 4-Chloro-2-nitroaniline 
• 7722-84-1 dihydrogen peroxide 
• 7732-18-5 water 
• 7782-50-5 chlorine 
• 28689-08-9 1,5-dichloro-2,3-dinitrobenzene 
• 7664-41-7 ammonia 
• 13898-47-0 hypochloric acid 

Downstream Products

• 65078-75-3 N-(2,4-dichloro-6-nitrophenyl)acetamide 
• 200618-13-9 chloro-acetic acid-(2,4-dichloro-6-nitro-anilide) 
• 618-62-2 3,5-dichloro-1-nitrobenzene 
• 34283-94-8 2,3,5-trichloronitrobenzene 
• 189576-09-8 1,5-dichloro-2-iodo-3-nitrobenzene 
• 5233-04-5 3,5-dichloro-1,2-phenylenediamine 
• 106391-02-0 N-(2,4-Dichloro-6-nitro-phenyl)-2-[3-hydroxy-5-oxo-4-phenyl-5H-furan-(2E)-ylidene]-2-phenyl-acetamide 
• 57660-38-5 2,4-dichloro-6-nitrophenylazide 
• 561320-82-9 1,5-dichloro-2-(3-methylbut-2-enyl)-3-nitrobenzene 
• 1026739-16-1 2,5-dichloro-3-[4,6-dichloro-7-(3-methyl-but-2-enyl)-1H-indol-3-yl]-[1,4]benzoquinone 
• 860682-53-7 N,N'-(3,5-dichloro-o-phenylene)-bis-benzamide 
• 82326-55-4 4,6-dichloro-1H-benzo[d]imidazole 
• 122509-70-0 C₈H₅Cl₂NO₃ 
• 1224955-42-3 C₁₀H₆Cl₂N₂O₂ 

Relevant articles and documents

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Sodium lauryl sulfate-catalyzed oxidative chlorination of aromatic compounds

Chlorination of commercially important aromatic compounds using sodium chloride as chlorine source and sodium periodate as oxidant in acidic medium catalyzed by sodium lauryl sulfate (SLS) led to the chloro-substituted aromatics in good yields and purity. Addition of sodium lauryl sulfate led to increased chlorination rate, better yield, excellent purity, and better quality of end product. The advantages of the present method are greater yield, excellent purity, and shorter reaction time at room temperature. Also dichlorinated product can be obtained by increasing the amount of sodium chloride and sodium periodate at slightly higher temperature (40C).

Oxidative Cyclizations. VII. Cyclization of 2-Substituted Anilines with Alkaline Hypohalite

The Green-Rowe oxidation of 2-nitroanilines with alkaline hypohlorite, to yield benzofuroxans, is demonstrated by studies of the visible spectra of transient intermediates to proceed through N-chlorination and a singlet nitrene.Two variations on the route to the nitrene are possible.The cyclization step is represented as an internal capture of the nitrene by the ortho substituent, and on this basis the Green-Rowe oxidative cyclization is now extended to anilines whose ortho substituent is benzoyl or phenylazo.It is not however successful for ortho phenyl.Azo compounds were observed as byproducts in some of these reactions, and are shown to arise via N,N-dichloroanilines.