2683-43-4

Usage

Uses

Used in Chemical Synthesis:
2,4-DICHLORO-6-NITROANILINE is used as a chemical intermediate for the synthesis of various compounds, particularly those with pharmaceutical or industrial applications. Its unique structure allows for further functionalization and modification, making it a versatile building block in organic chemistry.
Used in Fluorescent pH Probes:
2,4-DICHLORO-6-NITROANILINE is used as a key component in designing faster-reacting, more intensely fluorescent pH probes based on the rhodamine spirolactam structure. These probes are essential tools in biological and chemical research, allowing for the precise measurement and monitoring of pH levels in various environments.
Used in Analytical Chemistry:
Due to its distinct chemical properties, 2,4-DICHLORO-6-NITROANILINE can be employed in analytical chemistry for the detection and quantification of specific substances. Its reactivity and fluorescence characteristics make it a valuable asset in the development of new analytical methods and techniques.
Used in Pharmaceutical Industry:
2,4-DICHLORO-6-NITROANILINE may also find applications in the pharmaceutical industry, where it can be utilized in the development of new drugs or drug candidates. Its unique structure and properties can be exploited to design molecules with specific biological activities, potentially leading to the discovery of novel therapeutic agents.
Used in Dye Manufacturing:
Given its yellow color, 2,4-DICHLORO-6-NITROANILINE can be used in the manufacturing of dyes and pigments for various industries, such as textiles, plastics, and printing. Its chemical stability and color properties make it a suitable candidate for the production of high-quality dyes with specific color characteristics.

InChI:InChI=1/C6H4Cl2N2O2/c7-3-1-4(8)6(9)5(2-3)10(11)12/h1-2H,9H2

Upstream product

• 60-29-7 diethyl ether 
• 59483-70-4 N,N-dichloro-2-nitroaniline 
• 69732-99-6 2,4-dichloro-N-nitro-aniline 
• 305-80-6 4-diazobenzenesulfonic acid 
• 6975-29-7 N-(2,4-dichlorophenyl)acetamide 
• 65078-75-3 N-(2,4-dichloro-6-nitrophenyl)acetamide 
• 100-34-5 benzene diazonium chloride 
• 554-00-7 2,4-Dichloroaniline 
• 64-19-7 acetic acid 
• 88-74-4 2-nitro-aniline 
• 89-63-4 4-Chloro-2-nitroaniline 
• 769-11-9 2-chloro-6-nitroaniline 
• 7722-84-1 dihydrogen peroxide 
• 7732-18-5 water 

Downstream Products

• 65078-75-3 N-(2,4-dichloro-6-nitrophenyl)acetamide 
• 200618-13-9 chloro-acetic acid-(2,4-dichloro-6-nitro-anilide) 
• 23742-33-8 Cyclopropanecarboxylic acid (2,4-dichloro-6-nitro-phenyl)-amide 
• 62902-30-1 2,4-dichloro-2',4',6,6'-tetranitrodiphenylamine 
• 57729-73-4 (2,4-Dichloro-6-nitro-phenyl)-(2,4-dinitro-6-trifluoromethyl-phenyl)-amine 
• 68105-40-8 1-(2-nitro-4,6-dichlorophenylamino)-2,4-dinitronaphthalene 
• 35693-92-6 2,4,6-trichlorobiphenyl 
• 106391-02-0 N-(2,4-Dichloro-6-nitro-phenyl)-2-[3-hydroxy-5-oxo-4-phenyl-5H-furan-(2E)-ylidene]-2-phenyl-acetamide 
• 57660-38-5 2,4-dichloro-6-nitrophenylazide 
• 7116-18-9 4,6-Dichlor-benzofurazan 
• 15944-77-1 4,6-dichlorobenzofuroxan 
• 860682-53-7 N,N'-(3,5-dichloro-o-phenylene)-bis-benzamide 
• 5233-04-5 3,5-dichloro-1,2-phenylenediamine 
• 618-62-2 3,5-dichloro-1-nitrobenzene 

Relevant academic research and scientific papers

Activator free, expeditious and eco-friendly chlorination of activated arenes by N-chloro-N-(phenylsulfonyl)benzene sulfonamide (NCBSI)

N-Chloro-N-(phenylsulfonyl)benzene sulfonamide (NCBSI) has been explored for the first time as a chlorinating reagent for direct chlorination of various activated arenes and heterocycles without any activator. A comparative in-silico study was performed to determine the electrophilic character for NCBSI and commercially available N-chloro reagents to reveal the reactivity on a theoretical viewpoint. The reagent was prepared by an improved method avoiding the use of hazardous t-butyl hypochlorite. This reagent was proved to be very reactive compared to other N-chloro reagents. The precursor of the reagent N-(phenylsulfonyl)benzene sulfonamide was recovered from aqueous spent, which can be recycled to synthesize NCBSI. The eco-friendly protocol was equally applicable for the synthesis of industrially important chloroxylenol as an antibacterial agent.

Sodium lauryl sulfate-catalyzed oxidative chlorination of aromatic compounds

Chlorination of commercially important aromatic compounds using sodium chloride as chlorine source and sodium periodate as oxidant in acidic medium catalyzed by sodium lauryl sulfate (SLS) led to the chloro-substituted aromatics in good yields and purity. Addition of sodium lauryl sulfate led to increased chlorination rate, better yield, excellent purity, and better quality of end product. The advantages of the present method are greater yield, excellent purity, and shorter reaction time at room temperature. Also dichlorinated product can be obtained by increasing the amount of sodium chloride and sodium periodate at slightly higher temperature (40C).

Method of preparing an explosive compound

A method of preparing 4,6-dinitro-5,7-diaminobenzofuroxan from 4,6-dichloenzofuroxan.

Oxidative Cyclizations. VII. Cyclization of 2-Substituted Anilines with Alkaline Hypohalite

The Green-Rowe oxidation of 2-nitroanilines with alkaline hypohlorite, to yield benzofuroxans, is demonstrated by studies of the visible spectra of transient intermediates to proceed through N-chlorination and a singlet nitrene.Two variations on the route to the nitrene are possible.The cyclization step is represented as an internal capture of the nitrene by the ortho substituent, and on this basis the Green-Rowe oxidative cyclization is now extended to anilines whose ortho substituent is benzoyl or phenylazo.It is not however successful for ortho phenyl.Azo compounds were observed as byproducts in some of these reactions, and are shown to arise via N,N-dichloroanilines.