28140-40-1Relevant articles and documents
ACETYLATED PRODRUGS FOR DELIVERY ACROSS THE BLOOD-BRAIN BARRIER
-
, (2019/11/12)
The present disclosure relates to pharmaceutical compositions including a compound derived from a parent compound having a hydroxyl or amino moiety, wherein the hydroxyl in the parent compound is presented as an ester in the compound or the amino in the parent compound is presented as an amide in the compound, and their use to prevent or treat neurological disease.
Advances in analysis and synthesis of myo-inositol-derivatives through resolution by crystallisation
Wewers, Wolfgang,Gillandt, Hartmut,Traub, Henner Schmidt
, p. 1723 - 1728 (2007/10/03)
A simple method for the preparation of both enantiomers of tetra-O-benzyl-myo-inositol is presented. This method is based on the resolution of stereoisomers by crystallisation. Starting with the known synthesis of four diastereomers using d-camphor dimeth
Stable axial-rich chair conformer of myo-inositol derivatives due to introduction of two adjacent bulky silyl protections
Yamada, Hidetoshi,Okajima, Kotaro,Imagawa, Hiroshi,Mukae, Tatsuya,Kawamura, Yoshiaki,Nishizawa, Mugio
, p. 3157 - 3160 (2007/10/03)
The ring-conformational change of myo-inositol derivatives by introducing two tert-butyldimethylsilyl, triisopropylsilyl, or tert-butyldiphenylsilyl groups into the 1,2-trans hydroxy groups - 3,4- and 4,5-positions - were investigated. The cyclohexane cores of the 4,5-bis-O-silylated derivatives with tert-butyldiphenylsilyl or triisopropylsilyl groups were present in the axial-rich chair form.