29110-75-6Relevant academic research and scientific papers
HYDRAZIDE DERIVATIVES AND THEIR SPECIFIC USE AS ANTIBACTERIAL AGENTS BY CONTROLLING ACINETOBACTER BAUMANNII BACTERIUM
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Page/Page column 49-50, (2020/09/08)
The present invention relates to compounds of the following general formula (I): or a pharmaceutically acceptable salt and/or solvate thereof, their use as a drug, in particular as antibacterial agent, notablyforpreventingand/or treating disorders associa
High yielding protocol for direct conversion of thiols to sulfonyl chlorides and sulfonamides
Sohrabnezhad, Samira,Bahrami, Kiumars,Hakimpoor, Farahman
, p. 256 - 264 (2019/02/06)
In this paper, a new method for oxidative chlorination of thiols to sulfonyl chlorides and sulfonamides using H2O2 in the presence of TMSCl is reported. The excellent yields, short reaction times, excellent efficiencies, low costs, and easy separation of products are the most important advantages of this method.
Modular Synthesis of Alkylarylazo Compounds via Iron(III)-Catalyzed Olefin Hydroamination
Zhang, Yan,Huang, Chenchao,Lin, Xinru,Hu, Qi,Hu, Boyue,Zhou, Yulu,Zhu, Gangguo
supporting information, p. 2261 - 2264 (2019/03/26)
A novel Fe-catalyzed olefin hydroamination with aryldiazo sulfones for accessing alkylarylazo compounds has been successfully developed. Aryldiazo sulfones are used as radical acceptors, and N-N double bonds will be regenerated when an arene sulfonyl grou
N-PHENYL-N'-PHENOXYCARBONYL-PHENYLSULFONHYDRAZIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME
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Paragraph 0040-0041, (2018/02/04)
The present invention relates to a N-phenyl-N'-phenoxycarbonyl-phenylsulfonhydrazide derivative with excellent inhibitory activity on PGE2 production, a method for preparing the same and a pharmaceutical composition comprising the same as an ac
Hit-to-lead optimization of phenylsulfonyl hydrazides for a potent suppressor of PGE2 production: Synthesis, biological activity, and molecular docking study
Kim, Minju,Lee, Sunhoe,Park, Eun Beul,Kim, Kwang Jong,Lee, Hwi Ho,Shin, Ji-Sun,Fischer, Katrin,Koeberle, Andreas,Werz, Oliver,Lee, Kyung-Tae,Lee, Jae Yeol
, p. 94 - 99 (2015/12/18)
Preliminary hit-to-lead optimization of a novel series of phenylsulfonyl hydrazide derivatives, which were derived from the high throughput screening hit compound 1 (IC50 = 5700 nM against PGE2 production), for a potent suppressor of
Efficient synthesis of aryl hydrazines using copper-catalyzed cross-coupling of aryl halides with hydrazine in PEG-400
Chen, Junmin,Zhang, Yimin,Hao, Wenyan,Zhang, Rongli,Yi, Fei
, p. 613 - 617 (2013/07/25)
An efficient and convenient method for the synthesis of aryl hydrazines is described via copper-catalyzed cross-coupling of aryl halides with aqueous hydrazine in PEG-400. This protocol is applicable to both electron-deficient and electron-rich aryl iodides and bromides, and even to sterically hindered substrates, giving aryl hydrazines in good to excellent yields.
Solvent free, highly chemoselective N and O-acylation on silica and silica magnesium oxide: A recyclable solid surface
Ghosh, Pranab,Mandal, Amitava
, p. 261 - 268 (2012/10/29)
Silica or silica/magnesium oxide mixed surface mediates the N and O-acylation, benzoylation or sulfonylation of hosts of substrates under solvent free conditions at ambient temperature with high chemoselectivity.
Synthesis of sulfonamides and sulfonic esters via reaction of amines and phenols with thiols using H2O2-POCl3 system
Bahrami, Kiumars,Khodaei, Mohammad M.,Abbasi, Jamshid
supporting information; experimental part, p. 5095 - 5101 (2012/07/28)
Phosphorus oxychloride efficiently promoted the synthesis of sulfonamides and sulfonic esters from thiols with hydrogen peroxide in the presence of Amberlite IRA-400 (OH-). This method has been applied to a variety of substrates including nucleophilic and sterically hindered amines, and also phenols with excellent yields of sulfonamides and sulfonic esters. In most cases these reactions are highly selective, simple, and clean, affording products in excellent yields and high purity.
An easy microwave-assisted synthesis of sulfonamides directly from sulfonic acids
De Luca, Lidia,Giacomelli, Giampaolo
, p. 3967 - 3969 (2008/09/19)
(Chemical Equation Presented) An easy and handy synthesis of sulfonamides directly from sulfonic acids or its sodium salts is reported. The reaction is performed under microwave irradiation, has shown a good functional group tolerance, and is high yielding.
An efficient synthesis of sulfonylhydrazides and sulfonylsemicarbazides by utilizing alumina as a catalyst
Safaei-Ghomi, Javad
, p. 1561 - 1563 (2008/09/16)
Sulfonyl hydrazides and sulfonyl semicarbazides are readily prepared by the reacting of hydrazine derivatives with sulfonyl chlorides in the presence of basic alumina under solvent-free conditions. Reaction of a sulfonyl chloride with t-butylcarbazate, followed by hydrolysis provides the corresponding sulfonyl hydrazides in higher yield and shorter time than previously reported.
