3137-64-2Relevant articles and documents
Aziridination of α,β-unsaturated esters bearing allylic hydroxy groups with 3-acetoxyaminoquinazolinones: Evidence for a mechanism comprising Michael addition-SN2 nucleophilic displacement of acetoxy for aziridination of α,β-unsaturated esters
Atkinson, Robert S.,Williams, Paul J.
, p. 1951 - 1959 (1996)
Aziridinations of the allylic alcohol-bearing α,β-unsaturated esters 6 and 7 and their corresponding acetates 8 and 9 have been carried out under standard conditions using 3-acetoxyaminoquinazolinone 2. Whereas the preferred sense of diastereoselectivity
Aziridination of Electron-rich Acyclic Allylic alcohols using 3-Acetoxyaminoquinazolinones
Atkinson, Robert S.,Fawcett, John,Russell, David R.,Williams, Paul J.
, p. 3241 - 3244 (1995)
The products from aziridination of the phenyl-substituted allylic alcohols 6 and 7 with 3-acetoxyaminoquinazolinones 1 and 15 have been compared with those from aziridination of the methyl ester analogues 2, and 3: the differences in diastereoselectivities using these electron-rich and electron-deficient alkenes are ascribed to the intervention of transition states 8 and 4 respectively.
Imination of sulfoxides using 3-acetoxyaminoquinazolinone as nitrogen source in the presence of hexamethyldisilazane
Karabuga, Semistan,Kazaz, Cavit,Kilic, Hamdullah,Ulukanli, Sabri,Celik, Ayhan
, p. 5225 - 5227 (2005)
The reaction of 3-acetoxyaminoquinazolinone (QNHOAc) with various sulfoxides in the presence of HMDS as an acetic acid scavenger, afforded the corresponding sulfoximides in good yields. Sulfoximidation of phenyl methyl sulfoxide using a Q*NHOAc having a s
Visible-light- And bromide-mediated photoredox Minisci alkylation of N-heteroarenes with ester acetates
Deng, Guo-Jun,Huang, Huawen,Shi, Hang,Wang, Chunlian
supporting information, p. 9177 - 9181 (2021/11/16)
A visible-light-induced photoredox Minisci alkylation reaction of N-heteroarenes with ethyl acetate has been reported. The low-toxic ethyl acetate was used for the first time as an alkylation reagent. Hence, 4-quinazolinones, quinolines and pyridines reacted smoothly in the current reaction system. Mechanistic studies indicate that LiBr plays a key role to dramatically improve the efficiency of the reaction by the mediation of hydrogen atom transfer. This journal is
Cobalt-Catalyzed Tandem Transformation of 2-Aminobenzonitriles to Quinazolinones Using Hydration and Dehydrogenative Coupling Strategy
Samim, Sk. Abdus,Roy, Bivas Chandra,Nayak, Sourav,Kundu, Sabuj
, p. 11359 - 11367 (2020/10/12)
A tandem synthesis of quinazolinones from 2-aminobenzonitriles is demonstrated here by using an aliphatic alcohol-water system. For this transformation, a cheap and easily available cobalt salt and P(CH2CH2PPh2)3 (PP3) ligand were employed. The substrate scope, scalability, and synthesis of natural products exhibited the vitality of this protocol.
