37951-12-5Relevant articles and documents
Neuroprotective potential of synthetic mono-carbonyl curcumin analogs assessed by molecular docking studies
Abdulaziz, Osama,Ahmad, Shujaat,Alghamdi, Saad,Almehmadi, Mazen,Ghias, Mehreen,Hussain, Haya,Kamal, Zul,Khan, Farman Ali,Khan, Nasir Mehmood,Muhammad, Juma,Rahman, Shafiq Ur,Shah, Syed Wadood Ali,Ullah, Abid
, (2021/12/04)
Cognitive decline in dementia is associated with deficiency of the cholinergic system. In this study, five mono-carbonyl curcumin analogs were synthesized, and on the basis of their prom-ising in vitro anticholinesterase activities, they were further inve
Synthesis and Cytotoxicity of Diarylpentanoids against Sensitive CCRF-CEM and Multidrug-Resistant CEM/ADR5000 Leukemia Cells
Di Chio, Carla,Efferth, Thomas,Ettari, Roberta,Schirmeister, Tanja,Zhou, Min,Zappalà, Maria
, (2022/01/04)
This article described the synthesis and biological investigation of a series of symmetric diarylpentanoids, characterized by a dienone moiety and by a different pattern of substitution on the two phenyl rings. The series of compounds 1a–p were tested aga
Second harmonic generation in pyrazoline derivatives of dibenzylideneacetones and chalcone: A combined experimental and theoretical approach
de Araújo, Raiane Sodré,de Alcantara, Aline Moreira,Abeg?o, Luis M.G.,de Souza, Yago Pereira,Brand?o Silva, Ant?nio Carlos,Machado, Rogério,Joatan Rodrigues, José,Rodriguez Pliego, Josefredo,d'Errico, Francesco,Siqueira Valle, Marcelo,de Alencar, Márcio André Rodrigues Cavalcanti
, (2019/11/13)
In this work, we investigate theoretically and experimentally second harmonic generation (SHG) in three pyrazoline compounds, being two derivatives of dibenzylideneacetone (DBA) (C23H20N2 and C25H24N2O2) and one derivative of chalcone (C21H18N2). The compounds were synthesized after two steps employing a Claisen-Schmidt condensation followed by an addition-elimination reaction with phenylhydrazine. All compounds were characterized using NMR, FT-IR, UV-Vis, and XRD. We calculated the first-order hyperpolarizabilities of these molecules using program packages based on the time-dependent Hartree-Fock (TDHF) and density functional theory (DFT). SHG was characterized by Kurtz and Perry's powder method. We observed that these organic crystals present SHG efficiencies up to 5 times larger than the KDP, and we associated these values to their molecular structure and crystalline arrangements. The values obtained experimentally and theoretically evidence that these compounds have good potential for application in electronic devices based on second-order nonlinear responses.