40428-87-3

Usage

Uses

Used in Perfumery Industry:
Ethanone, 1-[3-(1-methylethyl)phenyl](9CI) is used as a fragrance ingredient for its pleasant aroma, contributing to the creation of various perfumes and scented products.
Used in Flavorings Industry:
This chemical compound is utilized as a flavoring agent, enhancing the taste and aroma of food and beverage products.
Used in Pharmaceutical Industry:
Ethanone, 1-[3-(1-methylethyl)phenyl](9CI) is employed in the development of pharmaceuticals due to its potential medicinal properties, offering a wide range of therapeutic applications.
Used in Cosmetic and Personal Care Products:
This ketone compound serves as a fragrance ingredient in cosmetic and personal care products, providing a pleasant scent and enhancing the overall user experience.
Used in Antimicrobial Applications:
Ethanone, 1-[3-(1-methylethyl)phenyl](9CI) has been studied for its potential antimicrobial properties, making it a valuable compound in the development of new drugs and treatments.
Used in Antioxidant Applications:
Its potential antioxidant properties have positioned Ethanone, 1-[3-(1-methylethyl)phenyl](9CI) as a promising candidate for the development of functional foods and nutraceuticals, contributing to health and wellness.

Upstream product

• 77344-62-8 1-(2,5-diisopropyl-phenyl)-ethanone 
• 75-29-6 isopropyl chloride 
• 98-86-2 acetophenone 
• 7446-70-0 aluminium trichloride 
• 98-82-8 Isopropylbenzene 
• 107-06-2 1,2-dichloro-ethane 
• 75-36-5 acetyl chloride 
• 87771-42-4 1-(3-(prop-1-en-2-yl)phenyl)ethanone 
• 5433-01-2 1-bromo-3-isopropylbenzene 
• 78191-00-1 N-Methoxy-N-methylacetamide 
• 1429312-27-5 3-isopropyl-N-methoxy-N-methylbenzamide 
• 75-16-1 methylmagnesium bromide 
• 5651-47-8 3-isopropylbenzoic acid 
• 12203-34-8 (η(6)-iso-propylbenzene)chromium tricarbonyl 

Downstream Products

• 457928-76-6 (E)-3-(3-isopropylphenyl)but-2-enoic acid ethyl ester 
• 135473-66-4 [1-Amino-1-(3-isopropyl-phenyl)-ethyl]-phosphonic acid 
• 135510-27-9 [1-Amino-1-(3-isopropyl-phenyl)-ethyl]-phosphonic acid diethyl ester 
• 135473-52-8 [1-Benzylamino-1-(3-isopropyl-phenyl)-ethyl]-phosphonic acid diethyl ester 
• 1438984-07-6 (S)-N-(1-(3-isopropylphenyl)ethyl)-1-(3-methoxybenzyl)-2-methyl-1H-benzo[d]imidazole-5-carboxamide 
• 1438984-08-7 (S)-1-(3-hydroxybenzyl)-N-(1-(3-isopropylphenyl)ethyl)-2-methyl-1H-benzo[d]imidazole-5-carboxamide 
• 1438984-09-8 (S)-methyl 2-(3-((5-(((S)-1-(3-isopropylphenyl)ethyl)carbamoyl)-2-methyl-1H-benzo[d]imidazol-1-yl)methyl)phenoxy)propanoate 
• 1438983-77-7 (S)-2-(3-((5-(((S)-1-(3-isopropylphenyl)ethyl)carbamoyl)-2-methyl-1H-benzo[d]imidazol-1-yl)methyl)phenoxy)propanoic acid 
• 1439933-29-5 (S)-N-((S)-1-(3-isopropylphenyl)ethyl)-2-methylpropane-2-sulfinamide 
• 1213971-65-3 (S)-1-(3-isopropylphenyl)ethanamine 
• 1438983-62-0 (S)-1-(4-chlorobenzyl)-N-(1-(3-isopropylphenyl)ethyl)-1H-benzo[d]imidazole-5-carboxamide 
• 1438984-02-1 (S,E)-N-(1-(3-isopropylphenyl)ethylidene)-2-methylpropane-2-sulfinamide 
• 1439933-15-9 (S)-3-(4-((5-((1-(3-isopropylphenyl)ethyl)carbamoyl)-1H-benzo[d]imidazol-1-yl)methyl)phenyl)picolinic acid 
• 1439933-38-6 (S)-methyl 3-(4-((5-((1-(3-isopropylphenyl)ethyl)carbamoyl)-1H-benzo[d]imidazol-1-yl)methyl)phenyl)picolinate 

Relevant academic research and scientific papers

CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE

Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with the enzyme ceramide galactosyltransferase (CGT), such as, for example, lysosomal storage diseases. Examples of lysosomal storage diseases include, for example, Krabbe disease and Metachromatic Leukodystrophy.

MCT4 INHIBITORS FOR TREATING DISEASE

Disclosed herein are compounds and compositions useful in the treatment of MCT4 mediated diseases, such as proliferative and inflammatory diseases, having the structure of Formula I: Methods of inhibition MCT4 activity in a human or animal subject are als

N-BENZYLBENZIMIDAZOLE MODULATORS OF PPARG

The invention provides molecular entities that bind with high affinity to PPARG (PPAR?), inhibit cdk5-mediated phosphorylation of PPARG, but do not exert an agonistic effect on PPARG. Compounds of the invention can be used for treatment of conditions in patients wherein PPARG plays a role, such as diabetes or obesity. Methods of preparation of the compounds, bioassay methods for evaluating compounds of the invention as non-agonistic PPARG binding compounds, and pharmaceutical compositions are also provided.

N-BIPHENYLMETHYLBENZIMIDAZOLE MODULATORS OF PPARG

The invention provides molecular entities that bind with high affinity to PPARG (PPAR?), inhibit cdk5-mediated phosphorylation of PPARG, but do not exert an agonistic effect on PPARG. Compounds of the invention can be used for treatment of conditions in patients wherein PPARG plays a role, such as diabetes or obesity. Methods of preparation of the compounds, bioassay methods for evaluating compounds of the invention as non-agonistic PPARG binding compounds, and pharmaceutical compositions are also provided.

ARYLSUBSTITUTED THIAZOLOTRIAZOLES AND THIAZOLOIMIDAZOLES

This disclosure relates to compounds, compositions and methods for the treatment of various disorders. In particular, the disclosure relates to thiazolotriazole and thiazoloimidazole compounds which agonize the activity of the protein TGR5. Formula (I)

Process for the production of a dihydroxybenzene and dicarbinol from diisopropylbenzene

Improved methods for the simultaneous production of dihydroxybenzene and dicarbinol from diisopropylbenzene are provided. These methods provide for continuous and simultaneous production of diisopropylbenzene dihydroperoxide (DHP) and diisopropylbenzene hydroxyhydroperoxide (HHP) using Karr Column extractors operated in series. A very high purity DHP-containing solution, the precursor to the dihydroxybenzene, can be produced according to the reported methods. A safe and efficient method for producing dicarbinol from HHP is also disclosed.

Biocatalysed synthesis of the enantiomers of the floral odorant Florhydral

The two enantiomers of the floral odorant Florhydral were prepared by enzymatic methods, and their olfactory properties were evaluated. (+)-Florhydral was found to be much more powerful than the (-)-enantiomer.

Synthesis of 2-indanones via [4 + 1] annulation reactions of (trialkylsilyl)arylketenes

(Matrix presented) (Trialkylsilyl)arylketenes combine with (trimethylsilyl)diazomethane in a new [4 + 1] annulation process leading to 2-indanone derivatives. The (trialkylsilyl)arylketene annulation substrates are available via the photochemical Wolff rearrangement of α-silyl-α-diazo ketones, which are themselves prepared by silylation of the corresponding diazo ketones. The mechanism of the annulation reaction is proposed to involve the formation of a 2,3-bis(silyl)cyclopropanone, which is in equilibrium with an oxyallylic cation. Electrocyclic closure of this intermediate forms the new cyclopentenone ring.