4728-02-3

Basic information

• Product Name: 3-benzoylpentane-2,4-dione
• CAS NO: 4728-02-3
• Molecular Formula: C₁₂H₁₂O₃
• Molecular Weight: 204.2219
• Mol File: 4728-02-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 316.5°C at 760 mmHg
• Flash Point: 132.5°C
• Density: 1.124g/cm³
• Vapor Pressure: 0.000408mmHg at 25°C
• Refractive Index: 1.515
• CAS DataBase Reference: 3-benzoylpentane-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzoylpentane-2,4-dione(4728-02-3)
• EPA Substance Registry System: 3-benzoylpentane-2,4-dione(4728-02-3)

Safety Data

• Hazardous Substances Data: 4728-02-3(Hazardous Substances Data)

Upstream product

• 60-29-7 diethyl ether 
• 15435-71-9 sodium acetylacetonate 
• 98-88-4 benzoyl chloride 
• 75-36-5 acetyl chloride 
• 13745-35-2 (1-methyl-1H-benzo[d]imdiazol-2-yl)(phenyl)methanone 
• 100-47-0 benzonitrile 
• 63446-76-4 1-methyl-1,3-bis(trimethylsilyloxy)buta-1,3-diene 
• 123-54-6 acetylacetone 
• 15435-71-9 sodium acetoacetonate 
• 463-51-4 Ketene 
• 93-91-4 1-phenylbutan-1,3-dione 

Downstream Products

• 1068-57-1 acetic acid hydrazide 
• 93-91-4 1-phenylbutan-1,3-dione 
• 114-83-0 1-acetyl-2-phenylhydrazine 
• 64-19-7 acetic acid 
• 56874-83-0 3-benzoyl-2,4-dichlorobenzaldehyde 
• 103-84-4 Acetanilid 
• 4435-51-2 1-phenyl-butane-1,2,3-trione 
• 65-85-0 benzoic acid 
• 34075-91-7 benzoylacetonatoboron difluoride 

Relevant articles and documents

SmCl3-catalyzed C-acylation of 1,3-dicarbonyl compounds and malononitrile

(Chemical Equation Presented) A recyclable, convenient, and efficient catalytic system for C-acylation of 1,3-dicarbonyl compounds and malononitrile with acid chlorides has been developed, giving moderate to excellent yields under mild conditions. This is the first catalytic example of such reactions. In addition, by applying this protocol as the key step, 3,5-disubstituted-1H- pyrazole-4-carboxylate can easily be synthesized in high yields in a one-pot procedure.

Catalytic action of azolium salts. VIII. Oxidative aroylation with arenecarbaldehydes catalyzed by 1,3-dimethylbenzimidazolium iodide

Refluxing of a mixture of benzaldehyde (1a), 1,3- dimethylbenzimidazolium iodide (7), p-nitroaniline (9b) as an oxidizing agent, and 1,8-diazabicyclo[5,4,0]-7-undecene (DBU) in MeOH afforded methyl benzoate (2a) in good yield. Other methyl arenecarboxylates 2 were similarly obtained from arenecarbaldehydes 1. We showed that this aroylation proceeds via the 2-aroyl-1,3-dimethylbenzimidazolium salt (8). The 1,2,4-triazolium salt (18) and the naphtho[1,2-d]imidazolium salt (19) were also effective catalysts for this oxidative aroylation. However, the aroylation did not proceed with the imidazolium salt (20). In the presence of flavins (25a - c), arenecarbaldehydes 1 reacted in MeOH under aerobic conditions catalyzed by the benzimidozolium salt 7 to give the corresponding methyl arenecarboxylates 2. 1-Methyl-3-[3-(10-phenylisoalloxazin-3-yl)propyl]benzimidazolium bromide (27) is an effective complex catalyst for this oxidative aroylation.