4773-96-0 Usage
Chemical Properties
Yellow powder
Uses
Different sources of media describe the Uses of 4773-96-0 differently. You can refer to the following data:
1. MAO inhibitor, immunostimulant
2. Mangiferin is a xanthonoid, a chemical compound found in mangoes and in Anemarrhena asphodeloides rhizomes. Mangiferin has effect of hepatinica and choleretic, and is used to therapy hepatitis. Mangif
erin is an anti-inflammatory, antivirotic, central nervous system inhibit function and immunologic suppression.
Mangiferin has curative effect on chronic bronchitis. Mangiferin has cytotoxicity effec
t on hepatocellular
carcinoma ce1l, and may induce apoptosis. Mangiferin has the effect of antioxidation and delaying caducity.
3. Mangiferin is a xanthonoid, a chemical compound found in mangoes and in Anemarrhena asphodeloides rhizomes. Mangiferin has effect of hepatinica and choleretic, and is used to therapy hepatitis. Mangiferin is an anti-inflammatory, antivirotic, central nervous system inhibit function and immunologic suppression. Mangiferin has curative effect on chronic bronchitis. Mangiferin has cytotoxicity effect on hepatocellularcarcinoma ce1l, and may induce apoptosis. Mangiferin has the effect of antioxidation and delaying caducity.
Definition
ChEBI: A C-glycosyl compound consisting of 1,3,6,7-tetrahydroxyxanthen-9-one having a beta-D-glucosyl residue at the 6-position.
General Description
Mangiferin (MGF) is a natural bioactive polyphenol predominantly isolated from the Mangifera indica (Mango) tree. It has a xanthone glucoside structure. Mangiferin can also be found in other angiosperm plants and herbs.
Biochem/physiol Actions
Mangiferin has various pharmacological properties including antioxidant, anti-diabetic, anti-bacterial, cardioprotective, neuroprotective, and immunomodulatory activities. It has also displayed antidiabetic, antihyperlipidemic, and antiatherogenic properties in streptozotocin-induced diabetic rats. MGF exerts chemotherapeutic and chemo-preventative activities. It displays antioxidant, analgesic, and hepatoprotective activity against carbon tetrachloride-induced liver injury. MGF is a known accelerator of gastrointestinal transit (GIT).
Check Digit Verification of cas no
The CAS Registry Mumber 4773-96-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,7,7 and 3 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 4773-96:
(6*4)+(5*7)+(4*7)+(3*3)+(2*9)+(1*6)=120
120 % 10 = 0
So 4773-96-0 is a valid CAS Registry Number.
InChI:InChI=1/C19H18O11/c20-4-11-15(25)17(27)18(28)19(30-11)12-8(23)3-10-13(16(12)26)14(24)5-1-6(21)7(22)2-9(5)29-10/h1-3,11,15,17-23,25-28H,4H2/t11-,15-,17+,18-,19?/m1/s1
4773-96-0Relevant articles and documents
-
Markham,K.,Wallace,J.
, p. 415 (1980)
-
Total synthesis of mangiferin, homomangiferin, and neomangiferin
Wei, Xiong,Liang, Danlin,Wang, Qing,Meng, Xiangbao,Li, Zhongjun
, p. 8821 - 8831 (2016/10/03)
Total synthesis of mangiferin, homomangiferin, and neomangiferin, three C-glycosyl xanthone natural products with a wide spectrum of pharmacological effects, has been achieved starting from 2,3,4,6-tetra-O-benzyl-α/β-d-glucopyranose. The key steps involve a stereoselective Lewis acid promoted C-glycosylation of protected phloroglucinol with tetrabenzylglucopyranosyl acetate and a highly regioselective base-induced cyclization for the construction of the core xanthone skeleton.
Synthesis of mangiferin, isomangiferin, and homomangiferin
Wu, Zhongtao,Wei, Guo,Lian, Gaoyan,Yu, Biao
supporting information; experimental part, p. 5725 - 5728 (2010/10/03)
Mangiferin, isomangiferin, and homomangiferin, the xanthone C-glycosides with a wide spectrum of pharmacological effects, were synthesized concisely, featuring a C-glycosylation of a xanthene derivative with perbenzylglucopyranosyl N-phenyltrifluoroacetimidate.