496035-49-5

Upstream product

• 67-56-1 methanol 
• 132969-62-1 (2'R,3'S,4'S,4R,5S)-3-[3'-hydroxy-5'-(4-methoxyphenyl)methoxy-2',4'-dimethylpentanoyl]-5-phenyl-4-methyl-2-oxazolidinone 
• 398518-77-9 (2R,3S,4S)-3-hydroxy-5-(4-methoxybenzyloxy)-2,4-dimethylpentanoic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 74-88-4 methyl iodide 
• 496035-35-9 (2S,4S)-1-hydroxy-5-(p-methoxybenzyloxy)-2,4-dimethylpentan-3-one 
• 827603-03-2 (2S,4S,5R)-6-(tert-butyldimethylsilyloxy)-5-hydroxy-1-(4-methoxybenzyloxy)-2,4-dimethylhexan-3-one 
• 827603-04-3 (2R,3R,4S,5S)-1-(tert-butyldimethylsilyloxy)-6-(4-methoxybenzyloxy)-3,5-dimethyl-hexane-2,4-diol 
• 133007-95-1 (2S,3R,4S)-5-[(4-methoxybenzyl)oxy]-2,4-dimethylpentane-1,3-diol 
• 182193-69-7 (S)-1-(p-methoxybenzyloxy)-2-methylpentan-3-one 
• 496035-36-0 (2R,3S,4S)-3-hydroxy-5-(4-methoxybenzyloxy)-2,4-dimethylpentanal 

Downstream Products

• 133007-95-1 (2S,3R,4S)-5-[(4-methoxybenzyl)oxy]-2,4-dimethylpentane-1,3-diol 
• 496035-37-1 methyl (2R,3S,4S)-3-(tert-butyldimethylsilyloxy)-2,4-dimethyl-5-(4-methoxybenzyloxy)pentanoate 
• 649756-12-7 methyl (2R,3S,4S)-3-triethylsilyloxy-5-(4-methoxybenzyloxy)-2,4-dimethylpentanoate 
• 132969-64-3 tert-Butyl-[(1S,2S)-1-((R)-2-iodo-1-methyl-ethyl)-3-(4-methoxy-benzyloxy)-2-methyl-propoxy]-dimethyl-silane 
• 132969-68-7 (2S,3R,4S,7S)-3-(tert-Butyl-dimethyl-silanyloxy)-7-methoxy-2,4-dimethyl-7-[3-(2-trimethylsilanyl-ethoxymethoxy)-phenyl]-heptan-1-ol 
• 132969-59-6 (2R,3R,4S,7S)-3-(tert-Butyl-dimethyl-silanyloxy)-7-methoxy-2,4-dimethyl-7-[3-(2-trimethylsilanyl-ethoxymethoxy)-phenyl]-heptanal 
• 132969-66-5 (4S,5R,6S)-5-(tert-Butyl-dimethyl-silanyloxy)-7-(4-methoxy-benzyloxy)-4,6-dimethyl-1-[3-(2-trimethylsilanyl-ethoxymethoxy)-phenyl]-heptan-1-one 
• 132969-67-6 (1S,4S,5R,6S)-5-(tert-Butyl-dimethyl-silanyloxy)-7-(4-methoxy-benzyloxy)-4,6-dimethyl-1-[3-(2-trimethylsilanyl-ethoxymethoxy)-phenyl]-heptan-1-ol 
• 132969-70-1 (2R,8S,9R,10S,13S)-9-(tert-Butyl-dimethyl-silanyloxy)-7-hydroxy-13-methoxy-1-(4-methoxy-benzyloxy)-2,4,4,8,10-pentamethyl-13-[3-(2-trimethylsilanyl-ethoxymethoxy)-phenyl]-tridecan-5-one 

Relevant academic research and scientific papers

A second-generation total synthesis of (+)-discodermolide: The development of a practical route using solely substrate-based stereocontrol

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SYNTHESIS OF DISCODERMOLIDE

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1,6-asymmetric induction in boron-mediated aldol reactions: application to a practical total synthesis of (+)-discodermolide.

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