510-13-4Relevant articles and documents
Computational and experimental analyses converge to reveal a coherent yet malleable aptamer structure that controls chemical reactivity
Tianjiao, Wang,Hoy, Julie A.,Lamm, Monica H.,Nilsen-Hamilton, Marit
, p. 14747 - 14755 (2009)
As short nucleic acids, aptamers in solution are believed to be structurally flexible. Consistent with this view, most aptamers examined for this property have been shown to bind their target molecules by mechanisms that can be described as "induced fit".
Kinetic exploration supplemented by spectroscopic and molecular docking analysis in search of the optimal conditions for effective degradation of malachite green
Dasmandal, Somnath,Mandal, Harasit Kumar,Rudra, Suparna,Kundu, Arjama,Majumdar, Tapas,Mahapatra, Ambikesh
, p. 38503 - 38512 (2015)
The degradation of malachite green (MG) by an alkaline hydrolytic process has been explored spectrophotometrically. The kinetics of the reaction have been meticulously studied under the influence of cationic alkyltrimethylammonium bromide (DTAB, TTAB and CTAB) surfactants, α-, β- and γ-cyclodextrins (CDs) and surfactant-β-CD mixed systems applying pseudo-first order conditions at 298 K. The surfactants and cyclodextrins individually catalyze the hydrolytic rate, whereas surfactant-β-CD mixed systems exhibit both an inhibiting and catalytic influence depending on the surfactant concentrations. The kinetic results have been explained precisely based on the pseudo-phase ion exchange (PIE) model of micelles and CD-catalyzed model of CD systems. The surfactants exhibit micellar surface catalysis, while CDs accelerate the rate by forming MG-CD inclusion complexes, thereby facilitating nucleophilic attack of its ionized secondary hydroxyl group on the carbocation center of MG. The encapsulation of MG within the supramolecular host cavity of the CDs has been investigated diligently using a steady-state absorption spectroscopic technique. The result shows 1:1 host-guest complexation with different relative orientations of the guest (MG) inside the hosts. Studies employing density functional theory (DFT) as well as molecular docking analysis provide valuable insight on the insertion mechanism. The results reveal that quantitative analysis can be utilized to predict the optimum conditions for the fastest degradation of MG in ambient environments.
Study of malachite green fading in water-ethanol-ethylene glycol ternary mixtures
Samiey, Babak,Ahmadi, Somayeh
, p. 151 - 164 (2013)
The rate constant of malachite green (MG+) alkaline fading was measured in water-ethanol-ethylene glycol ternary mixtures. This reaction was studied under pseudo-first-order conditions at 283-303 K. In each series of experiments, the concentration of ethanol was kept constant and the concentration of ethylene glycol was changed. It was shown that due to hydrogen bonding and hydrophobic interaction between MG+ and alcohol molecules the observed reaction rate constant, kobs, increased in the water-ethanol-ethylene glycol ternary mixtures. The fundamental rate constants of MG+ fading in these solutions (k1, k- 1 and k2) were obtained by the SESMORTAC model. Analysis of k1 and k2 values in solutions containing constant ethanol concentrations show that in low concentrations of ethylene glycol, hydrogen bonding formed between ethanol and ethylene glycol molecules and in high concentrations of ethylene glycol, ethanol as a solvent for ethylene glycol affected the reaction rate.
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Gilman,Jones
, p. 1243,1246 (1940)
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Kinetics of fading of some triphenylmethane dyes: Effects of electric charge, substituent, and aqueous binary mixtures of dimethyl sulfoxide and 2-propanol
Samiey,Dalvand
, p. 60 - 70 (2014/01/06)
The rate constants of alkaline fading of a number of triphenylmethane (TPM) dyes including methyl green (ME2+), brilliant green (BG +), fuchsin acid (FA2-), and bromophenol blue (BPB 2-) were obtained in aqueous binary mixtures of 2-propanol (protic solvent) and dimethyl sulfoxide (DMSO) (aprotic solvent) at different temperatures. It was observed that the reaction rate constants of BG+ and ME2+ increased and those of FA2- and BPB2- decreased with an increase in weight percentages of aqueous 2-propanol and DMSO binary mixtures. 2-Propanol and DMSO interact with the used TPM molecules through hydrogen bonding and ion-dipole interaction, respectively, in addition to their hydrophobic interaction with TPM dyes. The fundamental rate constants of a fading reaction in these solutions were obtained by the SESMORTAC model. Also, the effect of electric charge and substituent groups of a number of TPM dyes on their alkaline fading rate was studied.
