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Leucomalachite Green is a metabolite of Malachite Green, which is a colorless compound with various applications across different industries. It exhibits chemical properties such as being white to light brown, light green, or light blue in appearance.

129-73-7

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129-73-7 Usage

Uses

Used in Textile Industry:
Leucomalachite Green is used as a dye for directly coloring silk, wool, jute, and leather. It is also used for dyeing cotton after mordanting, providing a vibrant and lasting color to the fabric.
Used in Biological Research:
As a biological stain, Leucomalachite Green is employed in the study of various biological samples, aiding in the visualization and analysis of cellular structures and components.
Used in Clinical Research:
Leucomalachite Green serves as a clinical reagent, specifically for the inorganic phosphate assay, which is crucial in understanding various physiological processes and diagnosing certain medical conditions.
Used in Chemical Analysis:
The compound is used as a spot test reagent for detecting sulfurous acid and cerium, which are essential in identifying specific chemical compounds and their concentrations in various samples.
Used as an Acid-Base Indicator:
Leucomalachite Green functions as an acid-base indicator, with a color change at different pH levels. It turns yellow at pH 0.0, green at pH 2.0, and colorless at pH 14, making it a useful tool in determining the acidity or alkalinity of a solution.
Used in Medical Diagnostics:
Leucomalachite Green is a reagent for the quantitative colorimetric micro determination of hemoglobin and other heme compounds, which is vital in diagnosing and monitoring various blood-related disorders and conditions.

Purification Methods

Crystallise it from 95% EtOH (10mL/g), then from *benzene/EtOH, and finally from pet ether. [Beilstein 13 H 275, 13 II 89, 13 II 135, 13 III 529, 13 481.]

Check Digit Verification of cas no

The CAS Registry Mumber 129-73-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,2 and 9 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 129-73:
(5*1)+(4*2)+(3*9)+(2*7)+(1*3)=57
57 % 10 = 7
So 129-73-7 is a valid CAS Registry Number.

129-73-7 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • Alfa Aesar

  • (43758)  Leucomalachite Green   

  • 129-73-7

  • 2g

  • 137.0CNY

  • Detail
  • Alfa Aesar

  • (43758)  Leucomalachite Green   

  • 129-73-7

  • 10g

  • 655.0CNY

  • Detail
  • Sigma-Aldrich

  • (78567)  LeucomalachiteGreen  certified reference material, TraceCERT®

  • 129-73-7

  • 78567-25MG

  • 1,547.91CNY

  • Detail
  • Sigma-Aldrich

  • (78567)  LeucomalachiteGreen  certified reference material, TraceCERT®

  • 129-73-7

  • 78567-100MG

  • 2,337.66CNY

  • Detail
  • Sigma-Aldrich

  • (69669)  LeucomalachiteGreen  analytical standard

  • 129-73-7

  • 69669-25MG

  • 360.36CNY

  • Detail

129-73-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name LEUCOMALACHITE GREEN

1.2 Other means of identification

Product number -
Other names 4-[[4-(dimethylamino)phenyl]-phenylmethyl]-N,N-dimethylaniline

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:129-73-7 SDS

129-73-7Related news

Simultaneous determination of malachite green and its metabolite LEUCOMALACHITE GREEN (cas 129-73-7) in eel plasma using post-column oxidation09/27/2019

A rapid HPLC method with solid-phase extraction (SPE) clean-up for malachite green (MG) and leucomalachite green (LMG) in eel plasma was developed. MG and LMG were extracted with a buffered methanolic solution. The extract was subjected to aromatic sulphonic acid SPE. MG and LMG were eluted fr...detailed

129-73-7Relevant academic research and scientific papers

Solvent-free synthesis of 4,4-diaminotriarylmethanes-leuco malachite materials in the presence of FePO4

Behbahani, Farahnaz K.,Khademloo, Elham

, p. 1507 - 1510 (2014)

A fast, efficient and versatile route for the synthesis of 4,4-diaminotriarylmethanes is reported using N,N-dimethyl aniline and aryl aldehydes in presence of FePO4 under solvent-free condition at 100°C.

The novel two step synthesis of CuO/ZnO and CuO/CdO nanocatalysts for enhancement of catalytic activity

Kumaraguru, K.,Sankaran, A.

, (2020)

In the present investigation, Copper oxide (CuO)/Zinc oxide (ZnO) and CuO/cadmium oxide (CdO) nanocomposites (NCs) were fabricated by a simple two-step process involving co-precipitation technique and hydrothermal approach for the first time. The Powder X-ray Diffraction (PXRD) pattern demonstrates the existence of monoclinic, hexagonal and cubic phase structure of CuO/ZnO and CuO/CdO NCs. The absorption spectrum of the material was obtained via UV–Visible Spectroscopy and the band-gap value is calculated using Tauc's relation as 1.7 eV, 2.8 eV and 2.75 eV respectively for pure, CuO/ZnO and CuO/CdO NCs. The FESEM images gave the spherical and stone-like morphologies in the prepared CuO/ZnO and CuO/CdO NCs. At room temperature, CuO/ZnO and CuO/CdO NCs act as superior catalyst for the reduction of Rhodamine B (RhB) and Malachite Green (MG) dyes and degradation efficiency attained to be 77.26%, 73.15% for RhB and 79.82%, 74.69 for MG, respectively.

Metal- And solvent-free synthesis of aniline- And phenol-based triarylmethanes: Via Br?nsted acidic ionic liquid catalyzed Friedel-Crafts reaction

Jaratjaroonphong, Jaray,Saeeng, Rungnapha,Senapak, Warapong,Sirion, Uthaiwan,ponpao, nipaphorn

, p. 22692 - 22709 (2021/07/21)

A beneficial, scalable and efficient methodology for the synthesis of aniline-based triarylmethanes has been established through the double Friedel-Crafts reaction of commercial aldehydes and primary, secondary or tertiary anilines using Br?nsted acidic ionic liquid as a powerful catalyst, namely [bsmim][NTf2]. This protocol was successfully performed under metal- and solvent-free conditions with a broad range of substrates, giving the corresponding aniline-based triarylmethane products in good to excellent yields (up to 99%). In addition, alternative aromatic nucleophiles such as phenols and electron-rich arenes were also studied using this useful approach to achieve a diversity of triarylmethane derivatives in high to excellent yields. This journal is

Silver-catalyzed tandem 5- And 6-endo-cyclizationsviaconcomitant yne-ol-imine activation: selective entry to 2-aryldihydrofuroquinolines

Das, Prasanta,Karmakar, Swastik,Kundu, Sandip

, p. 16112 - 16118 (2021/09/22)

A silver(i) catalyzed domino imination-intramolecular biheterocyclization-aromatization cascade has been developed to construct 2-aryl/-heteroaryl dihydrofuroquinolines in moderate to good yield using an aldehyde and unprotected 4-(2-aminophenyl)but-3-yn-1-ol as precursors. Sequential Ag-(i)-induced 5-endo-digcyclization of the yne-ol part and 6-endo-trigcyclization of a proposed Ag-bound imine, followed by aromatization, furnish the furoquinoline derivatives.

Synthesis of Mannich-type derivatives from amides activated by hydrogen bonding with ZnCl2

Gong, Bozhen,Hu, Zhiyu,Jiang, Guofang,Le, Zhanggao,Xie, Zongbo,Zhu, Zhiqiang

supporting information, p. 9095 - 9099 (2020/11/30)

The amide group has one of the most significant functionalities found in many natural products. Herein, low-nucleophilic amides are used in a Mannich-type reaction to synthesize N-acyl-protected amine derivatives. A highly efficient synthetic method utilizing simple aldehydes, N-substituted anilines, and amides as substrates was established through a one-pot amide pathway activated by hydrogen bonding between the ZnCl2 and amide under solvent-free conditions. This strategy can be broadly applied to medicinal chemistry. More importantly, compared with the previous Lewis acid catalyzed reaction, we proposed a new application of zinc chloride. This journal is

COMPOSITIONS, METHODS, AND TEST KITS FOR DETERMINING AUTHENTICITY

-

Paragraph 0143-0144, (2019/04/30)

The present disclosure provides composition having at least one leuco composition conforming to Formula (I): [in-line-formulae]Ar1Ar2Ar3CH??(I)[/in-line-formulae] wherein Ar2 and Ar3 are independently a carbocyclic aryl or heteroaryl, and Ar1 is selected from the group consisting of: unsubstituted phenyl, electron deficient carbocyclic aryl, and heteroaryl. The present disclosure also provides a method of detecting an authentic composition and test kits for detecting authentic compositions.

LAUNDRY CARE COMPOSITIONS, METHODS, AND TEST KITS FOR DETERMINING AUTHENTICITY

-

Paragraph 0174-0177, (2019/04/29)

The present disclosure provides a laundry care composition having at least one laundry care ingredient and at least one leuco composition conforming to Formula (I): [in-line-formulae]Ar1Ar2Ar3CH??(I)[/in-line-formulae] wherein Ar2 and Ar3 are independently a carbocyclic aryl or heteroaryl, and Ar1 is selected from the group consisting of: unsubstituted phenyl, electron deficient carbocyclic aryl, and heteroaryl. The present disclosure also provides a method of determining an authentic laundry care composition and test kits for detecting authentic laundry care compositions.

Synthesis of symmetric triarylmethane derivatives catalyzed by AIL ionic liquid

Kang, Li Q.,Gao, Han,Cai, Yue Q.

, p. 57 - 62 (2017/12/06)

Abstract: An efficient, eco-friendly ionic liquid was described for the synthesis of symmetric triarylmethane derivatives via Baeyer condensation of N,N-dimethylaniline with different active aromatic aldehyde compounds using amide ionic liquid as a catalyst. The syntheses were achieved for the first time using amide ionic liquid as a catalyst eliminating the need for a volatile organic solvent. The advantages of this ionic liquid are low cost and operational simplicity.

Di- and triarylmethylium ions as probes for the ambident reactivities of carbanions derived from 5-benzylated Meldrum's acid

Chen, Xi,Tan, Yue,Berionni, Guillaume,Ofial, Armin R.,Mayr, Herbert

supporting information, p. 11069 - 11077 (2014/10/15)

The kinetics of the reactions of carbocations with carbanions 1 derived from 5-benzyl-substituted Meldrum's acids 1-H (Meldrum's acid=2,2-dimethyl-1,3- dioxane-4,6-dione) were investigated by UV/Vis spectroscopic methods. Benzhydryl cations Ar2CH+ added exclusively to C-5 of the Meldrum's acid moiety. As the second-order rate constants (kC) of these reactions in DMSO followed the linear free-energy relationship lg k=s N(N+E), the nucleophile-specific reactivity parameters N and s N for the carbanions 1 could be determined. In contrast, trityl cations Ar3C+ reacted differently. While tritylium ions of low electrophilicity (E-2) reacted with 1 through rate-determining β-hydride abstraction, more Lewis acidic tritylium ions initially reacted at the carbonyl oxygen of 1 to form trityl enolates, which subsequently reionized and eventually yielded triarylmethanes and 5-benzylidene Meldrum's acids by hydride transfer.

Solvent-free Br?nsted acid catalysed alkylation of arenes and heteroarenes with benzylic alcohols

Barbero, Margherita,Cadamuro, Silvano,Dughera, Stefano,Rucci, Marta,Spano, Giulia,Venturello, Paolo

, p. 1818 - 1826 (2014/03/21)

A simple and efficient alkylation of aromatic and heteroaromatic compounds via the direct SN1-type nucleophilic substitution of benzylic alcohols in the presence of catalytic amounts of the strong Br?nsted acid o-benzenedisulfonimide under neat conditions is herein reported. A library of di- and triaryl (and heteroaryl) methanes was prepared in good yields and high regioselectivity. The observed reactivity was shown to be in agreement with Mayr's nucleophilicity and electrophilicity scales.

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