52944-34-0

Basic information

• Product Name: P-CHLOROPROPYLBENZENE
• Synonyms: P-CHLOROPROPYLBENZENE;4-CHLOROPROPYLBENZENE;4-PROPYLCHLOROBENZENE;1-CHLORO-4-PROPYLBENZENE
• CAS NO: 52944-34-0
• Molecular Formula: C₉H₁₁Cl
• Molecular Weight: 154.64
• Mol File: 52944-34-0.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 203 °C
• Flash Point: 74.4°C
• Appearance: /
• Density: 1,01 g/cm3
• Vapor Pressure: 0.405mmHg at 25°C
• Refractive Index: 1.5110-1.5150
• Storage Temp.: 2-8°C
• CAS DataBase Reference: P-CHLOROPROPYLBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: P-CHLOROPROPYLBENZENE(52944-34-0)
• EPA Substance Registry System: P-CHLOROPROPYLBENZENE(52944-34-0)

Safety Data

• Hazard Codes: Xi,N,Xn
• Statements: 36/37/38-50/53-22
• Safety Statements: 26-36/37/39-61-60
• HazardClass: IRRITANT
• Hazardous Substances Data: 52944-34-0(Hazardous Substances Data)

Usage

General Description

P-chloropropylbenzene is a chemical compound with the molecular formula C9H11Cl. It is a colorless liquid with a faint, sweet odor, and is primarily used as an intermediate in the production of various other chemicals. P-chloropropylbenzene is a flammable substance and should be handled with caution. It is considered to be harmful if inhaled, absorbed through the skin, or ingested, and can cause irritation to the eyes, skin, and respiratory system. Additionally, prolonged or repeated exposure may lead to more severe health effects. P-chloropropylbenzene is also known by its CAS number 622-20-2 and is commonly used as a chemical reagent in industrial processes.

InChI:InChI=1/C9H11Cl/c1-2-3-8-4-6-9(10)7-5-8/h4-7H,2-3H2,1H3

Upstream product

• 6285-05-8 4'-chloropropiophenone 
• 106-46-7 para-dichlorobenzene 
• 2234-82-4 1-propylmagnesium chloride 
• 97-93-8 triethylaluminum 
• 98-56-6 4-chlorobenzotrifluoride 
• 827605-29-8 2-(4-chloro-phenyl)-5,5-dimethyl-[1,3,2]dioxaborinane 
• 540-54-5 1-Chloropropane 
• 599-91-7 propyl tosylate 
• 187737-37-7 propene 
• 108-90-7 chlorobenzene 
• 110-00-9 furan 
• 1679-18-1 4-Chlorophenylboronic acid 
• 84648-63-5 C₁₁H₁₁ClO₄ 
• 2696-84-6 4-propylaniline 

Downstream Products

• 912552-13-7 cis-(1R,2R)-1,2-dihydroxy-6-chloro-3-propylcyclohexa-3,5-diene 
• 29125-75-5 p-chloro(methylstyrene) 
• 77415-40-8 1-(4-Chlorophenyl)-1-propyl acetate 
• 103-65-1 phenylpropane 

Relevant articles and documents

Catalytic Synthesis of “Super” Linear Alkenyl Arenes Using an Easily Prepared Rh(I) Catalyst

Linear alkyl benzenes (LAB) are global chemicals that are produced by acid-catalyzed reactions that involve the formation of carbocationic intermediates. One outcome of the acid-based catalysis is that 1-phenylalkanes cannot be produced. Herein, it is reported that [Rh(μ-OAc)(η2-C2H4)2]2 catalyzes production of 1-phenyl substituted alkene products via oxidative arene vinylation. Since C C bonds can be used for many chemical transformations, the formation of unsaturated products provides a potential advantage over current processes that produce saturated alkyl arenes. Conditions that provide up to a 10:1 linear:branched ratio have been achieved, and catalytic turnovers >1470 have been demonstrated. In addition, electron-deficient and electron-rich substituted benzenes are successfully alkylated. The Rh catalysis provides ortho:meta:para selectivity that is opposite to traditional acid-based catalysis.

Copper-catalyzed cross-coupling reaction of organoboron compounds with primary alkyl halides and pseudohalides

Non-activated alkyl electrophiles, including alkyl iodides, bromides, tosylates, mesylates, and even chlorides, underwent copper-catalyzed cross-coupling with aryl boron compounds and alkyl 9-BBN reagents (see scheme; 9-BBN=9-borabicyclo[3.3.1]nonane). The reactions proceed with practically useful reactivities and thus complement palladium- and nickel-catalyzed Suzuki-Miyaura coupling reactions of alkyl halides.

Rapid defunctionalization of carbonyl group to methylene with polymethylhydrosiloxane-B(C6F5)3

The polymethylhydrosiloxane-B(C6F5)3 combination is found to be a versatile carbonyl defunctionalization system under mild and rapid conditions. For the first time, B(C6F5)3 has been used as a nonconventional Lewis acid catalyst to activate PMHS. Aromatic and aliphatic carbonyl compounds were effectively reduced to give the corresponding alkanes in high yields.