5329-89-5Relevant academic research and scientific papers
LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS
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Paragraph 0585, (2013/03/26)
Compounds, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds to treat, prevent or diagnose diseases, disorders, or conditions associated with one or more of the lysophosphatidic acid receptors are provided.
Multiscale charge injection and transport properties in self-assembled monolayers of biphenyl thiols with varying torsion angles
Masillamani, Appan Merari,Crivillers, Nuria,Orgiu, Emanuele,Rotzler, Juergen,Bossert, David,Thippeswamy, Ramakrishnappa,Zharnikov, Michael,Mayor, Marcel,Samori, Paolo
supporting information; experimental part, p. 10335 - 10347 (2012/10/08)
This article describes the molecular structure-function relationship for a series of biphenylthiol derivatives with varying torsional degree of freedom in their molecular backbone when self-assembled on gold electrodes. These biphenylthiol molecules chemisorbed on Au exhibit different tilt angles with respect to the surface normal and different packing densities. The charge transport through the biphenylthiol self-assembled monolayers (SAMs) showed a characteristic decay trend with the effective monolayer thickness. Based on parallel pathways model the tunneling decay factor β was estimated to be 0.27 A-1. The hole mobility of poly(3-hexylthiophene)-based thin-film transistors incorporating a biphenylthiol SAM coating the Au source and drain electrodes revealed a dependence on the injection barrier with the highest occupied molecular orbital (HOMO) level of the semiconductor. The possible role of the resistivity of the SAMs on transistor electrodes on the threshold voltage shift is discussed. The control over the chemical structure, electronic properties, and packing order of the SAMs provides a versatile platform to regulate the charge injection in organic electronic devices. Controlled charge injection! Biphenylthiols with different substituents between phenyl groups in the bridge position, once chemisorbed onto gold source-drain electrodes, can be used to vary the charge injection and electrical performances of organic thin-film transistors. By varying the torsion angle between the phenyl rings, one can introduce changes in packing densities and tilt angles of the molecules self-assembled on the electrode that play a direct role in influencing the charge transport through the molecular monolayer (see figure). Copyright
Diene-yne cyclisation reactions of 1-ethynyl-2-vinyl-3,4- dihydronaphthalenes and 1-ethynyl-2-vinylnaphthalenes
Watanabe, Masataka,Shiine, Kodai,Ldeta, Keiko,Matsumoto, Taisuke,Thiemann, Thies
experimental part, p. 669 - 678 (2009/09/06)
The reaction of 1-ethynyl-2-vinyl-3,4-dihydronaphthalenes and 1-ethynyl-2-vinylnaphthalenes over RuCI2(p-cymene) PPh3 leads to 9,10-dihydrophenanthrenes and phenanthrenes in those cases where the ethynyl group in the substrates carries a terminal proton. When 1-phenylethynyl-2-vinyl-3,4-dihydronaphthalenes or 1-phenylethynyl-2- vinylnaphthalenes are reacted over Pt(PPh3)4, 1-methylene-1H-benz[e]-4,5-dihydroindenes and 1-methylene-1H-benz[e]indenes are formed.
ANTI-ANDROGEN COMPOUNDS
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, (2008/06/13)
Disclosed are novel classes of anti-androgen including dihydrophenanthrene derivatives, their method of synthesis and their use in treating disorders associated with excessive androgenic activities.
RECHERCHES SUR LES SUBSTANCES MESOGENES-VIII; PREPARATION ET PROPERTIES MESOMORPHES DE SERIES ISOMETRIQUES
Malthete, Jacques,Canceill, Josette,Gabard, Jacqueline,Jacques, Jean
, p. 2815 - 2821 (2007/10/02)
The synthesis and the mesomorphic properties of various series of isometric mesogenic compounds are described.It is confirmed that isometric mesogenic molecules may be nematogenic and/or smectogenic according to the position of the polar rigid core.
