5405-95-8

Basic information

• Product Name: Benzene,1,1'-[oxybis(methylene)]bis[4-methoxy-
• Synonyms: Ether,bis(p-methoxybenzyl) (7CI,8CI); Bis(4-methoxybenzyl)ether; Bis(p-methoxybenzyl)ether; NSC 406876; NSC 5258; Toluene, a,a'-oxybis[p-methoxy-
• CAS NO: 5405-95-8
• Molecular Formula: C16H18 O3
• Molecular Weight: 258.317
• Mol File: 5405-95-8.mol
• Article Data: 42

Chemical Properties

• Boiling Point: 368.6°Cat760mmHg
• Flash Point: 124.5°C
• Density: 1.088g/cm³
• CAS DataBase Reference: Benzene,1,1'-[oxybis(methylene)]bis[4-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene,1,1'-[oxybis(methylene)]bis[4-methoxy-(5405-95-8)
• EPA Substance Registry System: Benzene,1,1'-[oxybis(methylene)]bis[4-methoxy-(5405-95-8)

Safety Data

• Hazardous Substances Data: 5405-95-8(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 105-13-5 4-Methoxybenzyl alcohol 
• 31525-65-2 3-methyl-but-2-enal dimethyl acetal 
• 123-11-5 4-methoxy-benzaldehyde 
• 141-78-6 ethyl acetate 
• 67-63-0 isopropyl alcohol 
• 64-17-5 ethanol 
• 67-56-1 methanol 
• 100-53-8 phenylmethanethiol 
• 111-88-6 Octanethiol 
• 122-91-8 4-methoxy-, benzenemethanol, formate 
• 89238-99-3 O-(4-methoxybenzyl)-trichloroacetimidate 
• 99-61-6 3-nitro-benzaldehyde 
• 100-51-6 benzyl alcohol 

Downstream Products

• 726-18-1 4,4'-dianisylmethane 
• 824-94-2 p-methoxybenzyl chloride 
• 104-20-1 4-(4-methoxyphenyl)-2-butanone 
• 1152-07-4 2-(4-methoxyphenyl)-3H-quinazolin-4-one 
• 1574184-70-5 5-methyl-2-(pyridin-2-yl)phenyl 4-methoxybenzoate 
• 123-11-5 4-methoxy-benzaldehyde 
• 100-09-4 4-methoxybenzoic acid 
• 1401733-61-6 (2-(1-(methoxyimino)ethyl)phenyl)(4-methoxyphenyl)methanone 
• 1510827-39-0 C₁₇H₁₉NO₂ 
• 1510826-79-5 (5-chloro-2-(1-(methoxyimino)ethyl)phenyl )( 4-methoxyphenyl)methanone 
• 1417412-29-3 (5-chloro-2-(1-(methoxyimino)ethyl)phenyl)(phenyl)methanone 
• 24318-43-2 4-methoxybenzyl 4-methoxybenzoate 
• 58647-73-7 2-[(4-methoxyphenyl)methyl]cyclopentanone 
• 105-13-5 4-Methoxybenzyl alcohol 

Relevant articles and documents

Zwitterion-induced organic-metal hybrid catalysis in aerobic oxidation

In many metal catalyses, the traditional strategy of removing chloride ions is to add silver salts via anion exchange to obtain highly active catalysts. Herein, we reported an alternative strategy of removing chloride anions from ruthenium trichloride using an organic [P+-N-] zwitterionic compound via multiple hydrogen bond interactions. The resultant organic-metal hybrid catalytic system has successfully been applied to the aerobic oxidation of alcohols, tetrahydroquinolines, and indolines under mild conditions. The performance of zwitterion is far superior to that of many other common Lewis bases or Br?nsted bases. Mechanistic studies revealed that the zwitterion triggers the dissociation of chloride from ruthenium trichloride via nonclassical hydrogen bond interaction. Preliminary studies show that the zwitterion is applicable to catalytic transfer semi-hydrogenation.

Aryl Boronic Acid Catalysed Dehydrative Substitution of Benzylic Alcohols for C?O Bond Formation

A combination of pentafluorophenylboronic acid and oxalic acid catalyses the dehydrative substitution of benzylic alcohols with a second alcohol to form new C?O bonds. This method has been applied to the intermolecular substitution of benzylic alcohols to form symmetrical ethers, intramolecular cyclisations of diols to form aryl-substituted tetrahydrofuran and tetrahydropyran derivatives, and intermolecular crossed-etherification reactions between two different alcohols. Mechanistic control experiments have identified a potential catalytic intermediate formed between the aryl boronic acid and oxalic acid.

Iodine-catalyzed transformation of aryl-substituted alcohols under solvent-free and highly concentrated reaction conditions

Iodine-catalyzed transformations of alcohols under solvent-free reaction conditions (SFRC) and under highly concentrated reaction conditions (HCRC) in the presence of various solvents were studied in order to gain insight into the behavior of the reaction intermediates under these conditions. Dimerization, dehydration and substitution were the three types of transformations observed with benzylic alcohols. Dimerization and substitution reactions were predominant in the case of primary- and secondary alcohols, whereas dehydration prevailed in the case of tertiary alcohols. The relative reactivity of substituted 1-phenylethanols in I2-catalyzed dimerization under SFRC provided a good Hammett plot ρ+ = -2.8 (r2 = 0.98), suggesting the presence of electron-deficient intermediates with a certain degree of developed charge in the rate-determining step.