603-52-1

Basic information

• Product Name: DIPHENYLURETHANE
• Synonyms: N,N-DIPHENYLURETHANE;ETHYL DIPHENYLCARBAMATE;ETHYL N,N-DIPHENYLCARBAMATE;DIPHENYLURETHANE;Carbamic acid, diphenyl-, ethyl ester;Diphenylcarbamic acid, ethyl ester;N,N-Diphenyl carbamic acid, ethyl ester;N,N-Diphenylethyl carbamate
• CAS NO: 603-52-1
• Molecular Formula: C₁₅H₁₅NO₂
• Molecular Weight: 241.29
• EINECS: 210-047-0
• Product Categories: Ethanes/ethenes;Nitrogen Compounds;Organic Building Blocks;Protected Amines
• Mol File: 603-52-1.mol
• Article Data: 8

Chemical Properties

• Melting Point: 70-72 °C(lit.)
• Boiling Point: 384.06°C (rough estimate)
• Flash Point: 171.5 °C
• Appearance: /
• Density: 1.0944 (rough estimate)
• Vapor Pressure: 2.29E-05mmHg at 25°C
• Refractive Index: 1.5200 (estimate)
• PKA: -2.99±0.50(Predicted)
• Water Solubility: 25.9mg/L at 20℃
• CAS DataBase Reference: DIPHENYLURETHANE(CAS DataBase Reference)
• NIST Chemistry Reference: DIPHENYLURETHANE(603-52-1)
• EPA Substance Registry System: DIPHENYLURETHANE(603-52-1)

Safety Data

• Safety Statements: S22:Do not inhale dust.; S24/25:Avoid contact with skin and eyes.
• WGK Germany: 3
• Hazardous Substances Data: 603-52-1(Hazardous Substances Data)

Usage

General Description

Ethyl diphenylcarbamate is an N-substituted ethyl carbamate and its mass spectra has been studied. The elimination kinetics of ethyl diphenylcarbamate was investigated over the temperature range of 349.9-440.0°C and the pressure range of 31-106Torr. Reaction was found to be homogeneous, unimolecular, and obey a first-order rate law. The products of the reaction were ethylene, carbon monoxide and the corresponding secondary amine.

Flammability and Explosibility

Notclassified

InChI:InChI=1/C15H15NO2/c1-2-18-15(17)16(13-9-5-3-6-10-13)14-11-7-4-8-12-14/h3-12H,2H2,1H3

Upstream product

• 122-39-4 diphenylamine 
• 105-58-8 Diethyl carbonate 
• 141-52-6 sodium ethanolate 
• 83-01-2 diphenylcarbamic chloride 
• 101-99-5 N-carboethoxyaniline 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 64-17-5 ethanol 
• 1228-96-2 1-[(diphenylamino)carbonyl]pyridinium chloride 
• 64-67-5 diethyl sulfate 
• 124-38-9 carbon dioxide 
• 52204-95-2 N-(diphenylcarbamoyl)-aziridine 
• 609-08-5 Diethyl methylmalonate 
• 83-13-6 diethyl 2-phenylmalonate 
• 541-41-3 chloroformic acid ethyl ester 

Downstream Products

• 1394948-86-7 3,5-dioxo-N,N-diphenylhexanamide 
• 75534-73-5 piperidine-1-carboxylic acid diphenylamide 
• 74-85-1 ethene 
• 124-38-9 carbon dioxide 
• 122-39-4 diphenylamine 
• 109124-48-3 tetraphenyl-oxalamide 
• 102078-86-4 N-carbobenzyloxydiphenylamine 
• 51084-03-8 N_.N_.N'.N'-Tetraphenylmethylmalonamid 
• 106993-46-8 N⁽¹⁾,N⁽¹⁾,N⁽³⁾,N⁽³⁾-tetraphenylmalonamide 
• 101584-41-2 diphenyl-carbamic acid isobutyl ester 
• 539-92-4 diisobutyl carbonate 
• 871883-16-8 (4-nitro-phenyl)-phenyl-carbamic acid ethyl ester 
• 871882-90-5 bis-(2,4-dinitro-phenyl)-carbamic acid ethyl ester 
• 1821-27-8 N,N-bis(p-nitrophenyl)amine 

Relevant articles and documents

Preparation method of amide compound

The invention discloses a preparation method of an amide compound. The preparation method comprises the following steps: enabling a solution A containing a compound I to react with a solution B containing n-butyllithium at -80 to 10 DEG C, and then enabling a reaction solution to react with a solution C containing a compound II at -80 to 10 DEG C, wherein the concentration of the compound I in the solution A is 5 to 40 percent by weight, the concentration of the compound II in the solution C is 5 to 50 percent by weight, flow rates of the solution A and the solution C are respectively 0.1 to 25 L/s and 0.1 to 1.5 L/s, n is an integer of 0 to 5, and R1 is separately C1 to C6 alkyl, C1 to C6 alkoxy or substituted or un-substituted C6 to C10 aryl; R2 is hydrogen, C1 to C6 alkyl, or substituted or non-substituted phenyl, and a substituting group substituting the phenyl is C1 to C6 alkyl or C1 to C6 alkoxy; and R3 is C1 to C6 alkyl or one or more phenyl-substituted methyl.

Ru-catalyzed hydrogenation of 3,5-diketo amides: Simultaneous control of chemo- and enantioselectivity

By modulating the chelating priorities of the different directing groups in 3,5-diketo amides with the assistance from coordinating solvent, highly chemo- and enantioselective hydrogenation of the C3-carbonyls was achieved in the presence of [RuCl(benzene)(S)-SunPhos]Cl in THF.

Correlation of the rates of solvolysis of the N,N-diphenylcarbamoylpyridinium ion

Solvolyses of the N,N-diphenylcarbamoylpyridinium ion are subject to specific and/or general base catalysis, which can be eliminated by addition of perchloric acid or increased, especially in fluoroalcohol-containing solvents, by addition of pyridine. The uncatalyzed solvolyses in aqueous methanol and aqueous ethanol involve a weakly nucleophilically assisted (l=0.22) heterolysis and the solvolyses in the pure alcohols are anomalously slow.