612-43-1

Usage

Uses

Used in Dye and Pigment Production:
2-Nitrobenzeneacrylic acid methyl ester is used as an intermediate in the synthesis of dyes and pigments for its ability to contribute to the color and stability of these compounds.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 2-Nitrobenzeneacrylic acid methyl ester is utilized as a building block in the development of various medicinal compounds, leveraging its chemical properties to enhance drug efficacy and function.
Used as a Corrosion Inhibitor:
2-Nitrobenzeneacrylic acid methyl ester is employed as a corrosion inhibitor in industrial applications, where it helps to protect materials from degradation and wear, particularly in environments exposed to harsh chemicals or conditions.
Used in Polymer Production:
As a monomer, 2-Nitrobenzeneacrylic acid methyl ester is used in the production of polymers, contributing to the formation of polymer chains with specific properties tailored for various applications.

InChI:InChI=1/C10H9NO4/c1-15-10(12)7-6-8-4-2-3-5-9(8)11(13)14/h2-7H,1H3/b7-6+

Upstream product

• 103-26-4 methyl cinnamate 
• 67-56-1 methanol 
• 612-41-9 2-nitrocinnamic acid 
• 21204-67-1 methyl (triphenylphosphoranylidene)acetate 
• 552-89-6 2-nitro-benzaldehyde 
• 103-26-4 Methyl cinnamate 
• 110-89-4 piperidine 
• 105-45-3 acetoacetic acid methyl ester 
• 612-41-9 2-nitrocinnamic acid 
• 96-32-2 bromoacetic acid methyl ester 
• 365-33-3 2-nitrobenzenediazonium tetrafluoroborate 
• 292638-85-8 acrylic acid methyl ester 
• 609-73-4 o-nitroiodobenzene 
• 577-19-5 2-nitrophenyl bromide 

Downstream Products

• 2001-33-4 o-nitrocinnamamide 
• 88939-75-7 methyl β-(o-aminophenyl)acrylate 
• 612-41-9 2-nitrocinnamic acid 
• 1202-04-6 indole-2-carboxylic acid methyl ester 
• 105404-33-9 (±)-methyl 2-oxo-1,2,3,4-tetrahydroquinoline-3-carboxylate 
• 59-31-4 2-quinolone 
• 88939-75-7 methyl (2E)-3-(2-aminophenyl)propenoate 
• 639478-88-9 3-(2-(nitroacetylamino)phenyl)propenonic acid methyl ester 
• 861536-82-5 2-nitro-cinnamic acid chloroamide 
• 1969-73-9 (2-nitrophenyl)acetaldehyde 
• 955009-86-6 3-biphenyl-4-yl-2-[(5-N,N-dibenzylaminopentyl)-N'-methylamino]-4-methoxycarbonylmethyl-3,4-dihydroquinazoline 
• 839672-50-3 methyl 3-[2-((4-biphenyl)iminomethyleneamino)phenyl]acrylate 
• 911840-04-5 methyl 3-[2-(3-(4-biphenyl)ureido)phenyl]acrylate 
• 592552-00-6 C₂₅H₂₈FN₃O₂ 

Relevant academic research and scientific papers

Photoinduced Regioselective Olefination of Arenes at Proximal and Distal Sites

The Fujiwara-Moritani reaction has had a profound contribution in the emergence of contemporary C-H activation protocols. Despite the applicability of the traditional approach in different fields, the associated reactivity and regioselectivity issues had

Preparation method of 3-(2-aminophenyl)-2-acrylate

The present invention relates to the field of pharmaceutical preparation technology, in particular a 3-(2-aminophenyl)-2-acrylate preparation method, comprising the following steps: 1) under the action of a base, o-nitrobenzaldehyde and malonate derivativ

One-Pot, Three-Step Synthesis of Benzoxazinones via Use of the Bpin Group as a Masked Nucleophile

The utilization of the Bpin group as a pronucleophile to facilitate the assembly of cyclic carbamates has been achieved. This one-pot process involves an initial copper-catalyzed borylation, a subsequent C-B bond oxidation to generate the reactive alcohol

Enantioselective Rauhut–Currier Reaction with β-Substituted Acrylamides Catalyzed by N-Heterocyclic Carbenes

β-Substituted acrylamides have low electrophilicity and are yet to be exploited in the enantioselective Rauhut–Currier reaction. By exploiting electron-withdrawing protection of the amide and moderate nucleophilicity N-heterocyclic carbenes, such substrates have been converted to enantioenriched quinolones. The reaction proceeds with complete diastereoselectivity, good yield, and modest enantioselectivity. Derivatizations are reported, as are computational studies, supporting decreased amide bond character with electron-withdrawing protection of the nitrogen.

Pd/Cu-free Heck and Sonogashira coupling reactions applying cobalt nanoparticles supported on multifunctional porous organic hybrid

A new heterogeneous cobalt catalyst has been synthesized by immobilizing Co species onto a nitrogen-rich porous organic polymer (Co@imine-POP). The heterogeneous catalyst synthesized was efficient in Heck and Sonogashira cross-coupling reactions in green media under mild reaction conditions without inert air and phase transfer agents. This phosphine-, copper-, and palladium-free catalyst was stable under the reaction conditions and could be reused for at least eight successive runs without a discernible decrease in its catalytic activity.

Access to [2,1]benzothiazine s,s-dioxides from β-substituted o-nitrostyrenes and sulfur

[2,1]Benzothiazine S,S-dioxides 2 were synthesized by simply heating o-nitrostyrenes with elemental sulfur in 3- picoline with complete atom economy. This reaction was found to occur without any added catalyst and consist of a cascade of reduction of the

In situ synthesis of carbon nanotube-encapsulated cobalt nanoparticles by a novel and simple chemical treatment process: Efficient and green catalysts for the Heck reaction

In this study, we present a novel, fast and easy method for supporting metal nanoparticles onto the internal surface of multi-walled CNTs; these CNT-encapsulated nanoparticles as heterogeneous, efficient, inexpensive and green catalysts promote the Heck cross-coupling of a large library of functional substrates under mild and sustainable conditions. Remarkably, the introduced catalytic system could be reused for at least nine successive runs without a discernible decrease in its catalytic activity.

Palladium-melamine complex anchored on magnetic nanoparticles: A novel promoter for C-C cross coupling reaction

A palladium-melamine complex deposited on Fe3O4@SiO2 nanoparticles (MNPs-Mel-Pd) was considered as an effective catalyst for C-C cross-coupling (Mirozoki-Heck) reaction. Surface and magnetic properties of the prepared core-shell hybrid nanocatalyst was characterized using Fourier transform infrared spectroscopy, X-ray diffraction, thermogravimetric analysis, energy-dispersive X-ray, vibrating sample magnetometry, transmission and scanning electron microscopy techniques and ICP/OES analysis. It was found that the heterogeneous nanocatalyst could be recovered simply and reused numerous times without loss of its catalytic activity. The advantages of this new methodology are: isolation of highly pure products without chromatography techniques, reusability of the catalyst using a magnet, easy workup procedure and negligible leaching of palladium.

Bis-quinoline-2-carboxylic acid Copper Salt as an Efficient Catalyst for Synthesis of Aryl Olefins by Heck Reaction

Abstract: A bis-quinoline-2-carboxylic acid copper salt as a single crystal was prepared and characterized by X-ray single crystal analysis. The crystal as a catalyst was applied to the Mizoroki–Heck coupling reaction between arylboronic acids and α-olefins. A series of diarylethenes and aryl olefins were synthesized with good to excellent yields at room temperature. The catalytic system exhibited good functional group tolerance and low pollution. Graphic Abstract: A bis-quinoline-2-carboxylic acid copper salt as a single crystal was prepared and characterized by X-ray single crystal analysis. The crystal as a catalyst was applied to the Mizoroki–Heck coupling reaction between arylboronic acids and α-olefins[InlineMediaObject not available: see fulltext.].

Pd nanoparticles immobilized on magnetic chitosan as a novel reusable catalyst for green Heck and Suzuki cross-coupling reaction: In water at room temperature

A novel type of magnetically responsive chitosan nanocomposite was successfully synthesized as a green and high powerful palladium-based heterogeneous catalyst and its efficiency in Heck and Suzuki cross-coupling was evaluated. This catalyst promote a large library of functional substrates of these reactions under mild and sustainable conditions (water or ethanol as solvent, at room temperature, in significantly short reaction time (20?minutes)) and stand as recyclable, metal scavenging catalytic systems.