62351-80-8Relevant academic research and scientific papers
Molecular properties of 5-(1H-Benzo[D]Oxa, thia, imid azole-2-Yl)-2-methyl quinazolin-4-ol fluorescent brighteners: Theoretical and experimental approach
Patil, Vikas,Sekar, Nagaiyan,Padalkar, Vikas S.,Rajput, Jamatsing,Patil, Sharad R.,Patil, Satish V.
, (2019/09/03)
A series of seven new fluorescent brighteners 5-(1H-benzo[d]oxazole, thiazole, imidazole-2-yl)-2-methyl quinazolin-4-ol were synthesized by chemical reaction of 2-Methyl-4-oxo-3,4-dihydroquinazoline-5-carboxylic acid and derivatives of 2-aminophenol/2-ami
Synthesis of 2-methyl-5-(5-phenyl substituted-1,3,4 oxadiazole-2-yl) quinazolin-4-one fluorescent brightening agent: Computational and experimental comparison of photophysical structure
Patil, Vikas,Padalkar, Vikas S.,Sekar, Nagaiyan,Patil, Satish V.,Rajput, Jamatsing
, p. 150 - 157 (2019/02/07)
Report is about the synthesized new range of oxadiazole substituted quinazoline and studied its electronic distribution to attribute fluorescent properties. B3LYP Density Functional Theory (DFT) computational optimization was studied to observe the effect
2-methyl-4-oxo-N-(4-oxo-2-phenyl substituted-1,3-thiazolidin-3-yl)-3,4- dihydroquinazoline-5-carboxamides - A new range of fluorescent whiteners: Synthesis and photophysical characterization
Patil, Vikas S.,Padalkar, Vikas S.,Sekar, Nagaiyan
, p. 1077 - 1086 (2014/07/22)
Fluorescent quinazolinones were synthesized form ethyl 2-methyl-4-oxo-3,4- dihydroquinazoline -5-carboxylate intermediate. The photophysical properties of the compounds were evaluated in DMF solvent. The experimental absorption and emission of the compoun
Metallo-β-lactamase inhibitory activity of 3-alkyloxy and 3-amino phthalic acid derivatives and their combination effect with carbapenem
Hiraiwa, Yukiko,Morinaka, Akihiro,Fukushima, Takayoshi,Kudo, Toshiaki
, p. 5841 - 5850 (2013/09/12)
3-Alkyloxy and 3-amino phthalic acid derivatives were found to have metallo-β-lactamase inhibitory activity. Among them, 3-amino phthalic acid derivatives showed both potent activity against metallo-β-lactamase, IMP-1 inhibitory activity and a strong combination effect with biapenem (BIPM), carbapenem antibiotic. In particular, the 4′-hydroxy-piperidine derivative showed strong IMP-1 inhibitory activity and a combination effect with various antibiotics.
FUSED TETRA OR PENTA-CYCLIC PYRIDOPHTHALAZINONES AS PARP INHIBITORS
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Page/Page column 48; 49, (2013/07/19)
Provided are certain fused tetra or penta-cyclic compounds and salts thereof, compositions thereof, and methods of use thereof.
Metallo-β-lactamase inhibitory activity of phthalic acid derivatives
Hiraiwa, Yukiko,Morinaka, Akihiro,Fukushima, Takayoshi,Kudo, Toshiaki
scheme or table, p. 5162 - 5165 (2010/03/24)
4-Butyl-3-methylphthalic acid was recognized as a metallo-β-lactamase inhibitor. The structure-activity relationship study of substituted phthalic acids afforded 3-phenylphthalic acid derivatives as potent IMP-1 inhibitors. On the other hand, 3-substituted with 4-hydroxyphenyl phthalic acid derivative displayed a potent combination effect with biapenem (BIPM) against Pseudomonas aeruginosa that produce IMP-1.
Anilines made easily: From aldehydes to tri-, tetra-, and pentasubstituted anilines in two steps
Neumann, Helfried,Von Wangelin, Axel Jacobi,Klaus, Stefan,Struebing, Dirk,Goerdes, Dirk,Beller, Matthias
, p. 4503 - 4507 (2007/10/03)
Easy as one, two, three. Highly substituted anilines are accessible with unprecedented efficiency from the three-component-coupling reaction of O-benzyl carbamate, aldehydes, and dienophiles followed by a new domino aromatization/deprotection reaction inv
Imidyl-benzenedicarboxylic acid derivatives
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, (2008/06/13)
New imidyl-benzenedicarboxylic acid derivatives, in particular 5-maleimidyl-isophthalic acid derivatives and 5-(nadic acid-imidyl)-isophthalic acid derivatives, and a process for their manufacture are described. These imidyl-benzenedicarboxylic acid deriv
