630-51-3

Usage

Uses

Used in Pharmaceutical Industry:
2,2,3,3-Tetramethylsuccinic acid, 97 is used as a chemical intermediate for the production of pharmaceuticals. It aids in the synthesis of various medicinal compounds, contributing to the development of new drugs and therapies.
Used in Agricultural Chemical Industry:
In the agricultural sector, 2,2,3,3-Tetramethylsuccinic acid, 97 is utilized as a building block for the synthesis of agricultural chemicals. It plays a role in the development of pesticides, herbicides, and other agrochemicals that help improve crop yield and protect plants from pests.
Used in Polymer Industry:
2,2,3,3-Tetramethylsuccinic acid, 97 is employed as a monomer or intermediate in the synthesis of polymers. It contributes to the development of various types of polymers with specific properties, such as high strength, durability, or flexibility, which can be used in different applications, including plastics, coatings, and adhesives.
Used in Research Laboratories:
2,2,3,3-Tetramethylsuccinic acid, 97 is used as a reagent in research laboratories for organic synthesis. It serves as a starting material or intermediate in various chemical reactions, enabling the synthesis of complex organic compounds for research purposes. Its high purity and stability make it an ideal choice for laboratory use.

InChI:InChI=1/C8H14O4/c1-7(2,5(9)10)8(3,4)6(11)12/h1-4H3,(H,9,10)(H,11,12)

Upstream product

• 78-67-1 2,2'-azobis(isobutyronitrile) 
• 3333-52-6 2,2,3,3-tetramethylsuccinonitrile 
• 79-31-2 isobutyric Acid 
• 110-22-5 diacetyl peroxide 
• 4212-43-5 perpropionic acid 
• 7664-93-9 sulfuric acid 
• 51513-36-1 2,4,4,5,5,7-hexamethyl-octane-3,6-dione 
• 64-19-7 acetic acid 
• 1133-23-9 1,2-di-isopropylidene-3,3,4,4-tetramethylcyclobutane 
• 10028-15-6 ozone 
• 592-41-6 1-hexene 
• 106-93-4 ethylene dibromide 
• 56-23-5 tetrachloromethane 

Downstream Products

• 35046-68-5 tetramethylsuccinic anhydride 
• 6144-77-0 3,3,4,4-tetramethyl-1-phenyl-pyrrolidine-2,5-dione 
• 10519-69-4 2,2,3,3-tetramethyl-1,4-butanediol 
• 3964-18-9 2,3-dimethyl-2,3-dinitrobutane 
• 13033-43-7 2,2,3,3-tetramethyl-N-phenyl-succinamic acid 

Relevant academic research and scientific papers

Reaction of Lithium Acylate α-Carbanions with Carbon Tetrabromide

Lithium acylate α-carbanions generated by metalation of acetic, butanoic, and 2-methylpropanoic acids with lithium diisopropylamide in THF under argon reacted with carbon tetrabromide at 20-25°C (2 h) to produce butanedioic acid or its 2,3-diethyl and 2,2,3,3-tetramethyl derivatives, as well as the corresponding 2-bromocarboxylic acids and bromoform. The effect of the halogen nature in carbon tetrahalide (CCl4, CBr4) on the reaction selectivity is discussed.

Reaction of Lithium Acylate α-Carbanions with Carbon Tetrachloride

Metalation of acetic, butanoic, or 2-methylpropanoic acid with lithium diisopropylamide in tetrahydrofuran under argon gave the corresponding lithium acylate α-carbanions which reacted with carbon tetrachloride at 20–25°C for 2 h to afford butanedioic acid or its 2,3-diethyl and 2,2,3,3-tetramethyl derivatives, as well as the corresponding α-chlorocarboxylic acids and chloroform. A radical mechanism was proposed for the formation of dicarboxylic and α-chlorocarboxylic acids.

Reactions of α-carbanions of lithium acylates with N,N-diethyl-N-chloro- and N,N-diethyl-N-bromoamines

The interaction of α-carbanions of lithium acylates (prepared via metalation of acetic, butyric, or isobutyric acid with lithium diisopropylamide in tetrahydrofuran under argon atmosphere) with N,N-diethyl-N-chloro- or N,N-diethyl-N-bromoamine has resulte

Reaction of α-carbanions of lithium acylates with 1,2-dibromoethane

The reaction of 1,2-dibromoethane with α-carbanions of lithium acylates generated from acetic, butyric, isobutyric, and capronic acids with lithium diisopropylamide has been studied. Anion-radical and anionic pathways of the products formation have been discussed.