6553-80-6Relevant articles and documents
Cryoelectrochemistry: Electrochemical reduction of 2(RS)-methyl 1-(tert-butoxycarbonyl)-2-iodomethyl-2,5-dihydropyrrole-2-carboxylate
Banks, Craig E.,Evans, Russell G.,Rodrigues, Jason,Turner, Peter G.,Donohoe, Timothy J.,Compton, Richard G.
, p. 2365 - 2372 (2005)
Cryoelectrochemisty with cyclic voltammetry and chronoamperometry has been applied to give an insight into a reductive pyrroline ring opening reaction, and has allowed the number of electrons participating in the reaction to be deduced from potential step experiments.
Low-Pressure Radical11C-Aminocarbonylation of Alkyl Iodides through Thermal Initiation
Chow, Shiao Y.,Odell, Luke R.,Eriksson, Jonas
, p. 5980 - 5989 (2016/12/26)
A radical11C-aminocarbonylation protocol characterized by excellent substrate compatibility was developed to transform alkyl iodides into11C-labelled amides, including the 11β-HSD1 inhibitor [carbonyl-11C]adamantan-1-yl(piperidin-1-yl)methanone. This protocol serves as a complementary extension of palladium-mediated11C-aminocarbonylation, which is limited to the preparation of11C-labelled compounds lacking beta-hydrogen atoms. The use of AIBN as a radical initiator and a low-pressure xenon–[11C]CO delivery unit represents a simple and convenient alternative to previous radical11C-carbonylation methodologies burdened with the need for a proprietary high pressure reactor connected to a light source.
Ester Formation via Nickel-Catalyzed Reductive Coupling of Alkyl Halides with Chloroformates
Zheng, Min,Xue, Weichao,Xue, Teng,Gong, Hegui
supporting information, p. 6152 - 6155 (2016/12/09)
The synthesis of alkyl esters from readily available alkyl halides and chloroformates was achieved for the first time using a mild Ni-catalyzed reductive coupling protocol. Unactivated primary and secondary alkyl iodides as well as glycosyl, benzyl, and aminomethyl halides were successfully employed to yield products in moderate to excellent yields with high functional group tolerance.
