82777-11-5

Basic information

• Product Name: 1-Hexanone, 6-bromo-1-phenyl-
• CAS NO: 82777-11-5
• Molecular Formula: C12H15BrO
• Molecular Weight: 255.155
• Mol File: 82777-11-5.mol
• Article Data: 24

Chemical Properties

• CAS DataBase Reference: 1-Hexanone, 6-bromo-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Hexanone, 6-bromo-1-phenyl-(82777-11-5)
• EPA Substance Registry System: 1-Hexanone, 6-bromo-1-phenyl-(82777-11-5)

Safety Data

• Hazardous Substances Data: 82777-11-5(Hazardous Substances Data)

Upstream product

• 20614-61-3 cyclohexyl-1-phenyl-1-hydroperoxide 
• 98-86-2 acetophenone 
• 13735-81-4 1-styrenyloxytrimethylsilane 
• 130250-59-8 6-bromo-N-methoxy-N-methylhexanamide 
• 100-58-3 phenylmagnesium bromide 
• 4224-70-8 6-bromohexanoic acid 
• 17851-49-9 5-hydroxypentyl phenyl ketone 
• 874338-00-8 C₁₂H₁₃BrO 
• 22809-37-6 6-bromohexanoyl chloride 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 102475-50-3 α-<4-(4-Methoxy-phenoxy)-butyl>-α-benzoyl-essigsaeure-aethylester 
• 1589-60-2 1-phenylcyclohexanol 
• 946-01-0 ε-chlorohexanophenone 
• 960-16-7 tributylphenylstannane 

Downstream Products

• 1452523-67-9 (R_S,R)-N-(tert-butylsulfinyl)-2-phenylazepane 
• 1452523-49-7 (R)-N-(6-bromo-1-phenylhexylidene)-2-methylpropane-2-sulfinamide 
• 1057648-56-2 6-(4'-(hydroxy(diphenyl)methyl)piperidin-1-yl)-1-phenylhexan-1-one 
• 188971-75-7 4-amino-5-chloro-2-methoxy-N-((1-(6-oxo-6-phenylhexyl)piperidin-4-yl)methyl)benzamide 
• 188973-81-1 tert-butyl [4-hydroxy-1-(6-oxo-6-phenyl)piperidin-4-ylmethyl]carbamate 
• 144227-15-6 (Z)-11-phenyl-1,5-dithiacycloundec-10-ene 
• 144227-14-5 (E)-11-phenyl-1,5-dithiacycloundec-10-ene 
• 144227-13-4 (Z)-10-phenyl-1,4-dithiacyclodec-9-ene 
• 144227-19-0 (Z)-2-phenyl-1-thiacyclohept-2-ene 
• 4471-05-0 1-phenylhexan-1-ol 
• 71919-91-0 ε-iodohexanophenone 
• 942-92-7 caprophenone 
• 852358-83-9 tert-butyl [1-(6-oxo-6-phenylhexyl)piperidin-3-ylmethyl]carbamate 
• 188973-83-3 tert-butyl [4-methoxy-1-(6-oxo-6-phenyl)piperidin-4-ylmethyl]carbamate 

Relevant articles and documents

Copper-catalyzed radical ring-opening halogenation with HX

An efficient copper-catalyzed radical ring-opening halogenation with HX (aq) is described. This protocol features redox-neutral conditions, green halogen sources, and a broad substrate scope, providing practical access to distally chlorinated, brominated and iodinated alkyl ketones and alkyl nitriles with moderate to good yields. This journal is

Far-end halogenated alkyl ketone taking HX as halogen source and synthesis method of far-end halogenated alkyl ketone

The invention relates to a far-end halogenated alkyl ketone taking HX as a halogen source and a synthesis method of the far-end halogenated alkyl ketone. The method comprises the following steps that: cycloalkyl peroxy alcohol and a copper acetate catalyst are added in a nitrogen atmosphere, then HCl, HBr and an HI solution are added as halogens, and stirring is carried out at normal temperature; after a reaction is finished, sufficient water is added to extract a reaction solvent N-methyl pyrrolidone, performing washing with saturated saline solution, an organic phase is dried with anhydrous sodium sulfate, the organic phase is concentrated under reduced pressure, so that the solvent can be removed; and column chromatography is performed on the organic phase to obtain a target product. According to the far-end halogenated alkyl ketone taking the HX as the halogen source and the synthesis method of the far-end halogenated alkyl ketoneinvention, industrial bulk raw materials HCl, HBr and an HI solution are used as the halogen source, free radical halogenation of C-C bond cracking is realized, and the far-end halogenated alkyl alkyl ketone compound is obtained with high yield; the byproduct of the reaction is water, so that the environmental pollution is reduced, and the industrial production benefit is greatly improved.

Ring-opening iodination and bromination of unstrained cycloalkanols through ?-scission of alkoxy radicals

Ring-opening iodination or bromination of unstrained cycloalkanols with NaI or NaBr and PhI(OAc)2 under visible light irradiation is developed. In this protocol the concentration of I2is modulated through the generation of triiodide (I3-), thus significantly avoiding undesired side reactions. The reaction is under mild conditions and has a wide substrate scope, thus providing a practically useful method for accessing ω-iodo or ω-bromoketones.