838-40-4

Basic information

• Product Name: 2,5-Diphenyl-1H-pyrrole
• Synonyms: 2,5-Diphenyl-1H-pyrrole;1H-Pyrrole, 2,5-diphenyl-
• CAS NO: 838-40-4
• Molecular Formula: C₁₆H₁₃N
• Molecular Weight: 219.29
• Mol File: 838-40-4.mol
• Article Data: 53

Chemical Properties

• Boiling Point: 415.1°C at 760 mmHg
• Flash Point: 174.5°C
• Appearance: /
• Density: 1.105g/cm³
• Vapor Pressure: 1.02E-06mmHg at 25°C
• Refractive Index: 1.622
• CAS DataBase Reference: 2,5-Diphenyl-1H-pyrrole(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Diphenyl-1H-pyrrole(838-40-4)
• EPA Substance Registry System: 2,5-Diphenyl-1H-pyrrole(838-40-4)

Safety Data

• Hazardous Substances Data: 838-40-4(Hazardous Substances Data)

Usage

General Description

2,5-Diphenyl-1H-pyrrole is a chemical compound with the molecular formula C16H13N. It is a heterocyclic aromatic compound consisting of a pyrrole ring with two phenyl groups attached at the 2 and 5 positions. 2,5-Diphenyl-1H-pyrrole is commonly used in the synthesis of organic compounds and is also known for its potential bioactive properties, such as anti-cancer and antimicrobial activities. Its unique chemical structure and reactivity make it a valuable building block in the development of pharmaceuticals and other organic materials.

InChI:InChI=1/C16H13N/c1-3-7-13(8-4-1)15-11-12-16(17-15)14-9-5-2-6-10-14/h1-12,17H

Upstream product

• 67421-66-3 2,5-diphenyl-1H-pyrrole-3-carbonitrile 
• 631-61-8 ammonium acetate 
• 495-71-6 phenacylacetophenone 
• 97405-82-8 2,2,3,3-tetradeuterio-1,4-diphenyl-1,4-butanedione 
• 7664-41-7 ammonia 
• 2085-90-7 1,4-diphenyl-1,4-butanediol 
• 111-27-3 hexan-1-ol 
• 637-59-2 1-Bromo-3-phenylpropane 
• 7654-06-0 3-phenyl-2H-azirine 
• 78388-87-1 1-(2,6-dichlorobenzoyl)-2,5-diphenylpyrrole 
• 78388-83-7 1-benzoyl-2,5-diphenylpyrrole 
• 107170-78-5 <(1-phenylvinyl)imino>tributylphosphorane 
• 70-11-1 α-bromoacetophenone 
• 103896-55-5 N-(1-Phenylvinylimino)triphenylphosphorane 

Downstream Products

• 206350-49-4 3-nitro-2,5-diphenyl-pyrrole 
• 110698-97-0 2,5-Diphenyl-3-formylpyrrole 
• 13220-01-4 (2,5-diphenyl-1H-pyrrol-3-yl)(phenyl)methanone 
• 109094-22-6 (2,5-diphenyl-pyrrol-3-ylmethyl)-dimethyl-amine 
• 75096-77-4 2,5-diphenyl-pyrrol-3-one oxime 
• 15969-46-7 2,6-diphenyl-3H-pyrimidin-4-one 
• 85814-61-5 1-(2,5-diphenyl-1H-pyrrol-3-yl)ethanone 
• 94905-31-4 2,5-diphenyl-pyrrole-1-carboxylic acid methyl ester 
• 1416451-03-0 N-(dimesitylboryl)-2,5-diphenylpyrrole 
• 70487-21-7 2,5-diphenyl-3-(p-tolyl)-1H-pyrrole 
• 65241-92-1 5-(4-methylphenyl)-2,3-diphenyl-1H-pyrrole 
• 70487-20-6 2,5-diphenyl-3-(o-tolyl)-1H-pyrrole 
• 3274-61-1 2,4,5-triphenylpyrrole 

Relevant articles and documents

P-Terphenyl as unexpected by-product in the synthesis of 2,5-diphenylpyrrole from acetophenone oxime and phenylacetylene

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Aerobic Oxidative Dehydrogenation of Ketones to 1,4-Enediones

An efficient and unprecedented strategy for the synthesis of 1,4-enediones from saturated ketones has been developed via palladium-catalyzed oxidative dehydrogenation. The protocol employs molecular oxygen as the sole oxidant and represents an atom- and step-economic process. The approach showed broad substrate scope, good functional group tolerance, and complete E-stereoselectivity. The reaction mechanism has been investigated through deuterium-labeling experiments and intermediate experiments.

Synthesis of 1,4-Dicarbonyl Compounds by Visible-Light-Mediated Cross-Coupling Reactions of α-Chlorocarbonyls and Enol Acetates

Herein, we report a protocol for visible-light-mediated radical coupling reactions of α-chloroketones and enol acetates to afford 1,4-dicarbonyl compounds, which are important precursors and intermediates in organic synthesis. The reaction involves photoredox-catalyzed activation of the α-chloroketone upon photoelectron transfer, carbon–chlorine bond cleavage, and coupling of the resulting radical with the carbon–carbon double bond of the enol acetate. This mild protocol has a wide substrate scope and moderate to good yields. (Figure presented.).