838-67-5

Usage

Uses

Used in Cosmetic Industry:
2-(benzylsulfanyl)-1-phenylethanol is used as a fragrance ingredient for its pleasant scent, contributing to the development of perfumes, lotions, and soaps. Its ability to impart a desirable aroma makes it a valuable addition to personal care products.
Used in Food and Beverage Industry:
In the food and beverage sector, 2-(benzylsulfanyl)-1-phenylethanol is utilized in the production of flavors and fragrances, enhancing the sensory experience of consumable products by adding depth and complexity to their taste and smell profiles.
Used in Pharmaceutical Industry:
Leveraging its antimicrobial and antibacterial properties, 2-(benzylsulfanyl)-1-phenylethanol has potential applications in the pharmaceutical industry, where it could be incorporated into formulations for disinfectant and cleaning products to ensure hygiene and prevent the spread of infections.
Used in Household Products Industry:
Similarly, its antimicrobial attributes make 2-(benzylsulfanyl)-1-phenylethanol suitable for use in household products, particularly those designed for cleaning and sanitizing surfaces, thus maintaining a hygienic environment in homes and other settings.

Upstream product

• 96-09-3 styrene oxide 
• 3492-64-6 sodium benzylmercaptide 
• 2408-88-0 2-benzylsulfanyl-1-phenylethanone 
• 3970-13-6 benzyl chloromethyl sulfide 
• 100-52-7 benzaldehyde 
• 826-20-0 Benzylmercaptomethyl-magnesiumchlorid 
• 100-53-8 phenylmethanethiol 
• 86317-56-8 (E)-styryl benzyl sulfide 
• 875778-80-6 2-[bis(benzylthio)methylene]-3-oxo-N-o-tolylbutanamide 
• 536-74-3 phenylacetylene 
• 1404591-81-6 (benzylthiomethyl)tributylstannane 
• 144-55-8 sodium hydrogencarbonate 
• 100-39-0 benzyl bromide 
• 100-44-7 benzyl chloride 

Downstream Products

• 100976-06-5 2-benzylsulphinyl-1-phenylethanol 
• 1404592-06-8 C₂₅H₂₃F₃O₃S 
• 190841-33-9 (1E)-3-((E)-1,3-diphenylallyloxy)-1,3-diphenylprop-1-ene 
• 131252-66-9 2.4-Diphenylbut-2-en-4-ol 
• 32093-01-9 trans-1-benzylsulfonyl-2-phenylethene 
• 1083-30-3 dihydrochalcone 
• 4663-33-6 1,3-diphenyl-3-hydroxypropene 
• 889862-46-8 trans-1-(1-phenylethylsulfonyl)-2-phenylethene 

Relevant academic research and scientific papers

Oxygen-to-Oxygen Silyl Migration of α-Siloxy Sulfoxides and Oxidation-Triggered Allicin Formation

Oxidation of α-siloxy thioethers leads to the formation of the corresponding sulfoxides as unstable intermediates, which undergo an intramolecular oxygen-to-oxygen silyl migration to break the C-S linkage. This process produces silyl protected sulfenic acids and subsequently thiosulfinates. It was used to develop oxidation-triggered allicin donors.

HBr/H2O2-mediated formation of C–S bond with thiosulfates

A novel, efficient, and green protocol to construct C–S bond has been developed via HBr/H2O2-mediated sulfenylation of styrenes and 4-hydroxycoumarins leading to unsymmetrical sulfides. Various unsymmetrical sulfides were prepared in one step with moderate to good yields using environmentally-friendly H2O2 as oxidant and HBr as catalyst. Based on the preliminary experimental results, a plausible reaction mechanism was proposed for HBr/H2O2-mediated formation of C–S bond with thiosulfates.

Odourless strategy for deep eutectic solvent-mediated ring opening of epoxides with in situ generated S -alkylisothiouronium salts

A general, straightforward and odourless ring-opening reaction allows the preparation of β-hydroxy sulfides from in situ generated S-alkylisothiouronium salts in urea-choline chloride-based deep eutectic solvent (DES). In addition, reaction of epoxides with thiourea in DES yields the corresponding thiiranes. Georg Thieme Verlag Stuttgart New York.

On the preparation and determination of configurational stability of chiral thio- and bromo[D1]methyllithiums

Thio- and bromo[D1]methyllithiums (ee 99%) were generated from the respective stannanes by tin-lithium exchange at temperatures ranging from 0 to -95 °C. Thio[D1]methyllithiums 6 were found to be microscopically configurationally labile on the time scale of the thiophosphate-α-mercaptophosphonate rearrangement even at -95 °C. Thio[D1]methyllithiums 13a and 13b underwent a thia-[2,3]-Wittig rearrangement down to -95 °C and 13b only down to -50 °C. The former were microscopically configurationally stable below -95 °C, and the latter racemized completely at -50 °C. Chiral bromo[D1]methyllithiums are chemically unstable at -78 °C but microscopically configurationally stable at the time scale of their addition to benzaldehyde and acetophenone.

JandaJel as a polymeric support to improve the catalytic efficiency of immobilized-1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD) under solvent-free conditions

JandaJel, with its greater spacing between the linear polymeric chains compared to that of polystyrene matrices, is a very efficient support for improving the catalytic efficiency of TBD under SolFC. The Royal Society of Chemistry.

Cyanuric chloride: An efficient catalyst for ring opening of epoxides with thiols under solvent-free conditions

2,4,6-Trichloro-1,3,5-triazine-catalyzed convenient and efficient ring opening of epoxides with thiols under solvent-free conditions is described. Short reaction time, mild reaction conditions, inexpensive and readily available catalyst, and excellent yie

NaOH-promoted thiolysis of oxiranes using 2-[bis(alkylthio)methylene]-3- oxo-N-o-tolylbutanamides as odorless thiol equivalents

A convenient and efficient protocol for the thiolysis of oxiranes using 2-[bis(alkylthio)methylene]-3-oxo-N-o-tolylbutanamides as thiol equivalents has been developed. Promoted by sodium hydroxide (NaOH) in ethanol at room temperature, the cleavage commences and the generated thiolate anions undergo nucleophilic addition in situ. β-Hydroxy Sulfides were obtained in high yields along with good β-regioselectivity, and trans β-hydroxy Sulfides were also isolated. The thiolysis of one α,β-epoxyketone product with the thiol equivalents was accomplished to afford the corresponding α-carbonyl sulfides in excellent yields. In all the cases, 3-oxo-N-o-tolylbutanamide, the precursor of the thiol equivalents, could be recovered in the novel thiolysis process as a byproduct in good yield. Georg Thieme Verlag Stuttgart.

The epoxy-Ramberg-Baecklund reaction (ERBR): A sulfone-based method for the synthesis of allylic alcohols

The epoxy-Ramberg-Baecklund reaction (ERBR) is outlined, in which α,β-epoxy sulfones are converted into a range of mono-, di- and tri-substituted allylic alcohols, on treatment with base. Modification of this method enabled the preparation of enantio-enriched allylic alcohols following the diastereoselective epoxidation of enantio-enriched vinyl sulfones that were accessed efficiently from the chiral pool. The scope, optimisation and limitations of the ERBR as a method for the preparation of allylic alcohols are discussed. Wiley-VCH Verlag GmbH & Co. KGaA, 2006.

The Epoxy-Ramberg-Backlund reaction: A new route to allylic alcohols

A new variant of the Ramberg-Backlund reaction is described, the epoxy-Ramberg-Backlund reaction (ERBR), in which α,β-epoxysulfones, on treatment with base, are converted into a range of mono-, di- and tri-substituted allylic alcohols. The scope and limitations of the ERBR are discussed.