90761-06-1

Upstream product

• 4530-20-5 BOC-glycine 
• 2666-93-5 (S)-Leu-OMe 
• 74805-42-8 N-carboxy-α-dehydrophenylalanine anhydride 
• 67-56-1 methanol 
• 108460-57-7 Boc-Gly-ΔPhe*NCA 
• 42267-16-3 (d,l)-phenylserine ethyl ester hydrochloride 
• 89093-60-7 2-(2-tert-Butoxycarbonylamino-acetylamino)-3-hydroxy-3-phenyl-propionic acid ethyl ester 
• 147781-99-5 Boc-Gly-DL-Phe(β-OH)-OH 
• 7517-19-3 methyl (L)-leucinate hydrochloride 
• 124194-31-6 Boc-Gly-Δ^ZPhe azlactone 

Downstream Products

• 64152-77-8 N-(tert-butyloxycarbonyl)glycyl-L-phenylalanyl-L-leucine methyl ester 
• 3982-70-5 ^tBOC-Gly-D-Phe-L-Leu-OMe 
• 84759-58-0 C₂₃H₃₃⁽²⁾H₂N₃O₆ 
• 84759-58-0 C₂₃H₃₃⁽²⁾H₂N₃O₆ 
• 108432-33-3 (S)-2-[(Z)-2-(2-tert-Butoxycarbonylamino-acetylamino)-3-phenyl-acryloylamino]-4-methyl-pentanoic acid 
• 125406-61-3 HCl*Gly-ΔPhe-(S)-Leu-OMe 
• 84759-58-0 C₂₃H₃₃⁽²⁾H₂N₃O₆ 
• 84759-58-0 C₂₃H₃₃⁽²⁾H₂N₃O₆ 
• 84759-64-8 HCl*H-Gly-L-Phe-L-Leu-OMe 
• 67582-05-2 1, D-Ala², L-Leu⁵-OMe>enkephalin 
• 93199-88-3 ^tBOC-Gly-ΔPhe-(S)-Leu-NH2 
• 84759-54-6 TFA-Gly-ΔPhe-(S)-Leu-OMe 
• 84759-56-8 (S)-4-Methyl-2-{3-phenyl-2-[2-(2,2,2-trifluoro-acetylamino)-acetylamino]-propionylamino}-pentanoic acid methyl ester 
• 93199-91-8 ^tBOC-Gly-ΔPhe-(S)-Leu-NHNHPh 

Relevant academic research and scientific papers

Dehydrooligopeptides. VII. Convenient Synthesis of Various Dehydrodi- and tripeptide Esters by Using N-Carboxy α-Dehydroamino Acid Anhydride

The one-pot syntheses of N-protected Δ1- and Δ2-dehydrodipeptide esters by the coupling of N-carboxy α-dehydroamino acid anhydride (ΔNCA) with several kinds of C- or N-protected L-α-amino acids are described.In addition, it was found that a similar coupling of ΔNCA with both C- and N-protected α-amino acids also took place to give Δ2-dehydrotripeptide derivatives, involving eight kinds of important C-terminal segments of antrimycins and cirratiomycins.The configurational confirmation of the α-dehydroisoleucine residue of the antibiotics is also discussed.

SYNTHESIS OF CHIRAL OLIGOPEPTIDES BY MEANS OF CATALYTIC ASYMMETRIC HYDROGENATION OF DEHYDROPEPTIDES

Asymmetric hydrogenation of Ac-ΔTyr(Ac)-(S)-Ala-Gly-OMe (6), Ac-ΔTyr(Ac)-(R)-Ala-Gly-(S)-Phe-OMe (7), Ac-ΔPhe-NH-CH(R)-CH2-OCH2Ph (10), HCO-ΔPhe-(S)-Leu-OMe (16), X-AA-ΔPhe-AA'-OMe ( 5: X=tBOC, CBZ, CF3CO; AA, AA'= α-amino acid ), and t

SYNTHESIS OF CHIRAL TRIPEPTIDES BY ASYMMETRIC HYDROGENATION OF DEHYDROPEPTIDES. REMARKABLE EFFECTS OF N-PROTECTING GROUPS ON STEREOSELECTIVITY AND REACTIVITY

Dehydrotripeptides, X-CH(Ri)-ΔPhe-CH(Rk)COOMe (3: X = tBOC-NH, CBZ-NH, CF3CONH and N3), were employed for the asymmetric hydrogenation catalyzed by chiral rhodium complexes and it was found that tBOC-3 brought a