91394-66-0

Basic information

• Product Name: 1-ACETAMIDO-4-BROMONAPHTHALENE
• Synonyms: 1-ACETAMIDO-4-BROMONAPHTHALENE;N-(4-BROMONAPHTHALEN-1-YL)ACETAMIDE;N-(4-BROMONAPHTHALENE-1-YL)-ACETAMIDE;N-ACETYL 4-BROMO-1-NAPHTHYLAMINE;N-(4-Bromo-1-naphthalen-1-yl)acetamide;1-Acetamido-4-bromoonaphthalene;1-Acetamido-4-bromonaphthalene 98%;1-Acetamido-4-bromonaphthalene98%
• CAS NO: 91394-66-0
• Molecular Formula: C₁₂H₁₀BrNO
• Molecular Weight: 264.12
• Product Categories: Amines;blocks;Bromides;Naphthalene derivatives
• Mol File: 91394-66-0.mol

Chemical Properties

• Melting Point: 160-163
• Boiling Point: 454.3 °C at 760 mmHg
• Flash Point: 228.6 °C
• Appearance: /
• Density: 1.528 g/cm³
• Vapor Pressure: 1.92E-08mmHg at 25°C
• Refractive Index: 1.69
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-ACETAMIDO-4-BROMONAPHTHALENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-ACETAMIDO-4-BROMONAPHTHALENE(91394-66-0)
• EPA Substance Registry System: 1-ACETAMIDO-4-BROMONAPHTHALENE(91394-66-0)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 91394-66-0(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
1-Acetamido-4-bromonaphthalene is used as a reagent for the formation of carbon-carbon bonds in various organic reactions. The presence of the bromine atom allows for easy functionalization and substitution, facilitating the synthesis of a wide range of organic compounds.
Used in Pharmaceutical Production:
1-Acetamido-4-bromonaphthalene is used as a key intermediate in the production of pharmaceutical products. Its unique structure and functional groups make it a valuable component in the development of new drugs and therapeutic agents.
Used as a Protecting Group in Organic Synthesis:
The acetamide group in 1-acetamido-4-bromonaphthalene can act as a protecting group for amines during organic synthesis. This allows chemists to temporarily block the reactivity of amine groups, enabling selective reactions to occur at other sites on the molecule.
Used in the Synthesis of Dyes and Pigments:
Due to its aromatic structure and bromine substitution, 1-acetamido-4-bromonaphthalene can be used in the synthesis of dyes and pigments, contributing to the development of new colorants for various applications.
Used in the Production of Advanced Materials:
The versatile chemical properties of 1-acetamido-4-bromonaphthalene make it suitable for the production of advanced materials, such as polymers, coatings, and composites, with tailored properties for specific applications.

InChI:InChI=1/C12H10BrNO/c1-8(15)14-12-7-6-11(13)9-4-2-3-5-10(9)12/h2-7H,1H3,(H,14,15)

Upstream product

• 7072-23-3 1,3-dibromo-5,5-dimethyl-hydantoin 
• 67-66-3 chloroform 
• 575-36-0 1-acetamidonaphthalene 
• 77-48-5 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione 
• 861294-59-9 N-(4,6,7-tribromo-5,6,7,8-tetrahydro-[1]naphthyl)-acetamide 
• 2298-07-9 4-Bromo-1-naphthylamine 
• 108-24-7 acetic anhydride 
• 134-32-7 1-amino-naphthalene 
• 64-19-7 acetic acid 
• 75-05-8 acetonitrile 
• 115348-05-5 1-acetamido-5,8-dihydronaphthalene 
• 7726-95-6 bromine 
• 6255-94-3 1-acetylamino-4-naphthalenesulfonic acid 
• 67-56-1 methanol 

Downstream Products

• 2298-07-9 4-Bromo-1-naphthylamine 
• 7499-73-2 N-(4-bromo-2-nitronaphthalen-1-yl)acetamide 
• 90-11-9 1-Bromonaphthalene 
• 51671-06-8 1-bromo-3-chloronaphthalene 
• 7499-65-2 4-bromo-2-nitronaphthalene 
• 74924-94-0 4-bromonaphthalene-2-amine 
• 1578179-15-3 2-(4-iodonaphthalen-2-ylamino)-5-nitrobenzoic acid 

Relevant articles and documents

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The invention relates to a preparation method of high-purity 1,4-dibromonaphthalene and belongs to the technical field of organic synthesis. The provided preparation method of high-purity 1,4-dibromonaphthalene aims to solve the problems that preparation methods of 1,4-dibromonaphthalene in the prior art are complicated, the reaction conditions are high, the product purity is low, the yield is low, and the product quality is unstable. The method comprises the four steps of a one-pot acetylation protection and selective bromination process, a hydrolysis deprotection process, a diazotization coupling reaction process and a recrystallization purification process to obtain high-purity 1,4-dibromonaphthalene. The provided preparation method has the advantages that the synthesis route is short,the reaction conditions are mild and easy to control, and the production cost is low. The organic synthesis reaction site is monotonous, the selectivity is high, the product purity is up to 99.0%, andthe total yield can reach 71.7%. Industrial production is easily realized, the need for large-scale production of 1,4-dibromonaphthalene can be effectively met, and the method has a broad applicationprospect.

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