946125-65-1

Basic information

• Product Name: 2-Fluoro-3-nitrobenzyl broMide
• Synonyms: 2-Fluoro-3-nitrobenzyl broMide;1-(bromomethyl)-2-fluoro-3-nitrobenzene
• CAS NO: 946125-65-1
• Molecular Formula: C₇H₅BrFNO₂
• Molecular Weight: 234.0225032
• Mol File: 946125-65-1.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 311.7±27.0 °C(Predicted)
• Appearance: /
• Density: 1.733±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-Fluoro-3-nitrobenzyl broMide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Fluoro-3-nitrobenzyl broMide(946125-65-1)
• EPA Substance Registry System: 2-Fluoro-3-nitrobenzyl broMide(946125-65-1)

Safety Data

• Hazardous Substances Data: 946125-65-1(Hazardous Substances Data)

Usage

General Description

2-Fluoro-3-nitrobenzyl bromide is a chemical compound with the molecular formula C7H5BrFNO2. It is a derivative of benzyl bromide and contains a nitro group and a fluorine atom attached to the benzene ring. 2-Fluoro-3-nitrobenzyl broMide is commonly used in organic synthesis and chemical research as a benzyl bromide derivative. It can be used as a reactant in various chemical reactions to introduce the benzyl bromide group into other organic molecules. Additionally, it can also be used as a precursor for the synthesis of various pharmaceuticals and agrochemicals. Due to its reactive nature, it should be handled with care and appropriate safety measures.

Upstream product

• 3970-40-9 2-chloro-3-nitrotoluene 
• 946126-95-0 (2-fluoro-3-nitrophenyl)methanol 
• 437-86-5 2-fluoro-3-nitrotoluene 
• 3970-35-2 2-chloro-3-nitrobezoic acid 
• 946126-94-9 2-fluoro-3-nitrobenzoic acid methyl ester 
• 53553-14-3 2-chloro-3-nitrobenzoic acid methyl ester 

Downstream Products

• 946130-07-0 2-(2-fluoro-3-nitrobenzyl)-3-oxo-butyric acid ethyl ester 
• 946130-13-8 3-(2-fluoro-3-nitrobenzyl)-7-hydroxy-4-methyl-2-oxo-2H-1-benzopyran 
• 946126-97-2 2-oxo-2H-3-(2-fluoro-3-aminobenzyl)-4-methyl-7-hydroxy-1-benzopyran 
• 946126-42-7 4-methyl-3-(2-fluoro-3-aminobenzyl)-7-(pyrimidin-2-yloxy)-2-oxo-2H-1-benzopyran 
• 946128-76-3 3-{2-fluoro-3-(methylaminosulfonyl)aminobenzyl}-4-methyl-7-(pyrimidin-2-yloxy)-2-oxo-2H-1-benzopyran 
• 946126-61-0 4-methyl-3-(2-fluoro-3-aminobenzyl)-7-(thiazol-2-yloxy)-2-oxo-2H-1-benzopyran 
• 946126-64-3 3-{2-fluoro-3-aminobenzyl}-4-methyl-7-(5-fluoropyrimidin-2-yloxy)-2-oxo-2H-1-benzopyran 
• 946126-67-6 3-(2-fluoro-3-aminobenzyl)-4-methyl-7-(benzothiazol-2-yloxy)-2-oxo-2H-1-benzopyran 
• 946129-85-7 2-{2-fluoro-3-[4-methyl-2-oxo-7-(pyrimidin-2-yloxy)-2H-1-benzopyran-3-ylmethyl]phenylsulfamoyl}-N-methylacetamide 
• 946127-42-0 4-fluoromethyl-3-(2-fluoro-3-aminobenzyl)-7-(thiazol-2-yloxy)-2-oxo-2H-1-benzopyran 
• 946126-93-8 C₂₃H₁₈FN₃O₇S 
• 946126-04-1 4-methyl-3-(2-fluoro-3-nitrobenzyl)-7-(pyrimidin-2-yloxy)-2-oxo-2H-1-benzopyran 
• 873697-71-3 methyl 4-[(2-fluoro-3-{[(6-methylpyridin-3-yl)carbamoyl]amino}phenyl)methyl]piperazine-1-carboxylate 

Relevant articles and documents

MEK INHIBITORS AND THERAPEUTIC USES THEREOF

The present disclosure provides compounds, compositions containing such compounds, and methods of designing, developing, producing and preparing compounds represented by general Formula (I), including pharmaceutically acceptable salts thereof or a synthetic intermediate thereof. The compounds act as MEK inhibitors and are capable of displaying one or more beneficial therapeutic effects, including treating cancer.

STING AGONISTS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same for the modulation of STING, and the treatment of STING-mediated disorders.

Benzoxazine compound and preparation method and application thereof

The invention discloses a benzoxazine compound, having a structure shown as in formula (I) that is shown in the description, or a pharmaceutically acceptable salt thereof; definitions of substituents in the formula (I) are shown in the description. In add