946126-04-1Relevant articles and documents
MEK INHIBITORS AND THERAPEUTIC USES THEREOF
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, (2021/07/17)
The present disclosure provides compounds, compositions containing such compounds, and methods of designing, developing, producing and preparing compounds represented by general Formula (I), including pharmaceutically acceptable salts thereof or a synthetic intermediate thereof. The compounds act as MEK inhibitors and are capable of displaying one or more beneficial therapeutic effects, including treating cancer.
p27 PROTEIN INDUCER
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, (2010/04/25)
The present invention provides a p27 protein inducing agent comprising a compound represented by general formula (11) below or pharmaceutically acceptable salt thereof as an active ingredient: wherein G1, G2, G3 and G8 are each independently selected from -N= etc., Ring G6 is selected from divalent aryl etc., A is selected from amino etc., G4 is selected from oxygen etc., G5 is selected from oxygen etc., G7 is selected from -CH2- etc., and R2 is selected from C1-6 alkyl etc.
