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Natural products, pharmaceutical and photoelectronic materials containing the fluorenone framework

February 29, 2024

  • Title:       

     Natural products, pharmaceutical and photoelectronic materials containing the fluorenone framework 

  • Image Source:

    Chemoselective Ruthenium-Catalyzed C-O Bond Activation: Orthogonality of Nickel-and Palladium-Catalyzed Reactions for the Synthesis of Polyaryl Fluorenones

  • Mark:

    Figure 1

  • Associated context:

    Over the past decade, fluoren-9-one derivatives have attracted considerable attention due to their presence in natural products1 with a range of biological activities (e.g.,  dengibsin,1d,g dengibsinin,1d dendroflorin,1b cauliphin)1j and  in pharmaceutically important agents (anticancer, antioxidant, and anti-HIV).2 Furthermore, fluorenones, arylated  fluorenones, and benzofluorenones have been incorporated  in oligomers and polymers which have been examined for  potential applications of their optical and electrochemical  properties as organic light-emitting devices3 and liquid  crystals4 (Figure 1).

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